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[1]
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NUCLEOTIDE SEQUENCE [MRNA].
TISSUE=Liver;
DOI=10.1083/jcb.109.6.3391; PubMed=2557354 [NCBI, ExPASy, EBI, Israel, Japan]
Zhang J.T.,
Nicholson B.J.;
"Sequence and tissue distribution of a second protein of hepatic gap junctions, Cx26, as deduced from its cDNA.";
J. Cell Biol. 109:3391-3401(1989).
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[2]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
TISSUE=Kidney;
DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan]
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
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[3]
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PROTEIN SEQUENCE OF 1-18.
DOI=10.1038/329732a0; PubMed=2823143 [NCBI, ExPASy, EBI, Israel, Japan]
Nicholson B.J.,
Dermietzel R.,
Teplow D.,
Traub O.,
Willecke K.,
Revel J.-P.;
"Two homologous protein components of hepatic gap junctions.";
Nature 329:732-734(1987).
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- FUNCTION: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
- SUBUNIT: A connexon is composed of a hexamer of connexins.
- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
- TISSUE SPECIFICITY: Liver, kidney, intestine, lung, spleen, stomach, testis and brain, but not heart and adult skeletal muscle.
- SIMILARITY: Belongs to the connexin family. Beta-type (group I) subfamily.
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Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms.
Distributed under the Creative Commons Attribution-NoDerivs License.
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| Length: 226 AA [This is the length of the unprocessed precursor] |
Molecular weight: 26451 Da [This is the MW of the unprocessed precursor] |
CRC64: E36EC95F1B235A0D [This is a checksum on the sequence] |
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10 20 30 40 50 60
MDWGTLQSIL GGVNKHSTSI GKIWLTVLFI FRIMILVVAA KEVWGDEQAD FVCNTLQPGC
70 80 90 100 110 120
KNVCYDHYFP ISHIRLWALQ LIMVSTPALL VAMHVAYRRH EKKRKFMKGE IKNEFKDIEE
130 140 150 160 170 180
IKTQKVRIEG SLWWTYTTSI FFRVIFEAVF MYVFYIMYNG FFMQRLVKCN AWPCPNTVDC
190 200 210 220
FISRPTEKTV FTVFMISVSG ICILLNITEL CYLFIRYCSG KSKRPV
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P21994 in FASTA format |
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ExPASy Home page
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