[1]	NUCLEOTIDE SEQUENCE [GENOMIC DNA]. STRAIN=FP-1; PubMed=2165135 [NCBI, ExPASy, EBI, Israel, Japan] Tartaglia J., Winslow J., Goebel S.J., Johnson G.P., Taylor J., Paoletti E.; "Nucleotide sequence analysis of a 10.5 kbp HindIII fragment of fowlpox virus: relatedness to the central portion of the vaccinia virus HindIII D region."; J. Gen. Virol. 71:1517-1524(1990).
[2]	NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. DOI=10.1128/JVI.74.8.3815-3831.2000; PubMed=10729156 [NCBI, ExPASy, EBI, Israel, Japan] Afonso C.L., Tulman E.R., Lu Z., Zsak L., Kutish G.F., Rock D.L.; "The genome of fowlpox virus."; J. Virol. 74:3815-3831(2000).
[3]	DISCUSSION OF SEQUENCE. DOI=10.1007/BF01702589; PubMed=8279127 [NCBI, ExPASy, EBI, Israel, Japan] Koonin E.V., Senkevich T.G.; "Fowlpox virus encodes a protein related to human deoxycytidine kinase: further evidence for independent acquisition of genes for enzymes of nucleotide metabolism by different viruses."; Virus Genes 7:289-295(1993).

Comments

CATALYTIC ACTIVITY: NTP + deoxycytidine = NDP + dCMP.
SIMILARITY: Belongs to the DCK/DGK family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

X17202; CAA35067.1; -; Genomic_DNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]
AF198100; AAF44403.1; -; Genomic_DNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]

PIR

D35216; D35216.

RefSeq

NP_039022.1; -.

3D structure databases

HSSP

P27707; 1P5Z. [HSSP ENTRY / PDB]

ModBase

P21974.

Ontologies

GO:0005524;	Molecular function: ATP binding (inferred from electronic annotation from InterPro).
GO:0004137;	Molecular function: deoxycytidine kinase activity (inferred from electronic annotation from EC).
GO:0016773;	Molecular function: phosphotransferase activity, alcohol group as acceptor (inferred from electronic annotation from InterPro).
GO:0006139;	Biological process: nucleobase, nucleoside, nucleotide and nucleic acid metabolic process (inferred from electronic annotation from InterPro).
QuickGo view.

Family and domain databases

InterPro

IPR002624; Deoxynucleoside_kinase.
Graphical view of domain structure.

PANTHER

PTHR10513; dNK; 1.

Pfam

PF01712; dNK; 1.
Pfam graphical view of domain structure.

ProtoNet

P21974.

Genome annotation databases

GeneID

1486607; -.

Other

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

ATP-binding; Kinase; Nucleotide-binding; Transferase.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 219`	`219`	`Probable deoxycytidine kinase FPV059.`	`PRO_0000175093`
`NP_BIND`	`16 23`	`8`	`ATP (Potential).`

Sequence information

Length: 219 AA [This is the length of the unprocessed precursor]

Molecular weight: 25909 Da [This is the MW of the unprocessed precursor]

CRC64: 4C3B08D885B58CE7 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MDSINEFTSK KLSIEGNISS GKTDVLNILR NINNVVSFHD VEDRYTPIEK ELIRKFHENP 

        70         80         90        100        110        120 
SRWSYALQTH YCMKRVRMHL ECFVPSRVNI LERSIFSDRY VFAEAATALG YMDDPEWALY 

       130        140        150        160        170        180 
CKQHDWYTDK LEIQFDGIIY LRTIPESCKE RINEKSITEK NYPNISIDYL KTLHEKHELW 

       190        200        210 
LTQCKKVPVL IIDGEEDFIF DPCAKKKLIN EVTEFINSI

P21974 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools