[1]
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NUCLEOTIDE SEQUENCE [MRNA].
TISSUE=Placenta;
PubMed=1707278 [NCBI, ExPASy, EBI, Israel, Japan]
Lundstroem K.,
Salminen M.,
Jalanko A.,
Savolainen R.,
Ulmanen I.;
"Cloning and characterization of human placental catechol-O-methyltransferase cDNA.";
DNA Cell Biol. 10:181-189(1991).
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[2]
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NUCLEOTIDE SEQUENCE [MRNA], AND VARIANT SER-34.
PubMed=1847521 [NCBI, ExPASy, EBI, Israel, Japan]
Bertocci B.,
Miggiano V.,
da Prada M.,
Dembic Z.,
Lahm H.-W.,
Malherbe P.;
"Human catechol-O-methyltransferase: cloning and expression of the membrane-associated form.";
Proc. Natl. Acad. Sci. U.S.A. 88:1416-1420(1991).
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[3]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA].
PubMed=8055944 [NCBI, ExPASy, EBI, Israel, Japan]
Tenhunen J.,
Salminen M.,
Lundstroem K.,
Kiviluoto T.,
Savolainen R.,
Ulmanen I.;
"Genomic organization of the human catechol O-methyltransferase gene and its expression from two distinct promoters.";
Eur. J. Biochem. 223:1049-1059(1994).
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[4]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
DOI=10.1038/ng1285; PubMed=14702039 [NCBI, ExPASy, EBI, Israel, Japan]
Ota T.,
Suzuki Y.,
Nishikawa T.,
Otsuki T.,
Sugiyama T.,
Irie R.,
Wakamatsu A.,
Hayashi K.,
Sato H.,
Nagai K.,
Kimura K.,
Makita H.,
Sekine M.,
Obayashi M.,
Nishi T.,
Shibahara T.,
Tanaka T.,
Ishii S.,
Yamamoto J., ![]()
Saito K.,
Kawai Y.,
Isono Y.,
Nakamura Y.,
Nagahari K.,
Murakami K.,
Yasuda T.,
Iwayanagi T.,
Wagatsuma M.,
Shiratori A.,
Sudo H.,
Hosoiri T.,
Kaku Y.,
Kodaira H.,
Kondo H.,
Sugawara M.,
Takahashi M.,
Kanda K.,
Yokoi T.,
Furuya T.,
Kikkawa E.,
Omura Y.,
Abe K.,
Kamihara K.,
Katsuta N.,
Sato K.,
Tanikawa M.,
Yamazaki M.,
Ninomiya K.,
Ishibashi T.,
Yamashita H.,
Murakawa K.,
Fujimori K.,
Tanai H.,
Kimata M.,
Watanabe M.,
Hiraoka S.,
Chiba Y.,
Ishida S.,
Ono Y.,
Takiguchi S.,
Watanabe S.,
Yosida M.,
Hotuta T.,
Kusano J.,
Kanehori K.,
Takahashi-Fujii A.,
Hara H.,
Tanase T.-O.,
Nomura Y.,
Togiya S.,
Komai F.,
Hara R.,
Takeuchi K.,
Arita M.,
Imose N.,
Musashino K.,
Yuuki H.,
Oshima A.,
Sasaki N.,
Aotsuka S.,
Yoshikawa Y.,
Matsunawa H.,
Ichihara T.,
Shiohata N.,
Sano S.,
Moriya S.,
Momiyama H.,
Satoh N.,
Takami S.,
Terashima Y.,
Suzuki O.,
Nakagawa S.,
Senoh A.,
Mizoguchi H.,
Goto Y.,
Shimizu F.,
Wakebe H.,
Hishigaki H.,
Watanabe T.,
Sugiyama A.,
Takemoto M.,
Kawakami B.,
Yamazaki M.,
Watanabe K.,
Kumagai A.,
Itakura S.,
Fukuzumi Y.,
Fujimori Y.,
Komiyama M.,
Tashiro H.,
Tanigami A.,
Fujiwara T.,
Ono T.,
Yamada K.,
Fujii Y.,
Ozaki K.,
Hirao M.,
Ohmori Y.,
Kawabata A.,
Hikiji T.,
Kobatake N.,
Inagaki H.,
Ikema Y.,
Okamoto S.,
Okitani R.,
Kawakami T.,
Noguchi S.,
Itoh T.,
Shigeta K.,
Senba T.,
Matsumura K.,
Nakajima Y.,
Mizuno T.,
Morinaga M.,
Sasaki M.,
Togashi T.,
Oyama M.,
Hata H.,
Watanabe M.,
Komatsu T.,
Mizushima-Sugano J.,
Satoh T.,
Shirai Y.,
Takahashi Y.,
Nakagawa K.,
Okumura K.,
Nagase T.,
Nomura N.,
Kikuchi H.,
Masuho Y.,
Yamashita R.,
Nakai K.,
Yada T.,
Nakamura Y.,
Ohara O.,
Isogai T.,
Sugano S.;
"Complete sequencing and characterization of 21,243 full-length human cDNAs.";
Nat. Genet. 36:40-45(2004).
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[5]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], AND VARIANT MET-158.
DOI=10.1186/gb-2004-5-10-r84; PubMed=15461802 [NCBI, ExPASy, EBI, Israel, Japan]
Collins J.E.,
Wright C.L.,
Edwards C.A.,
Davis M.P.,
Grinham J.A.,
Cole C.G.,
Goward M.E.,
Aguado B.,
Mallya M.,
Mokrab Y.,
Huckle E.J.,
Beare D.M.,
Dunham I.;
"A genome annotation-driven approach to cloning the human ORFeome.";
Genome Biol. 5:RESEARCH84.1-RESEARCH84.11(2004).
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[6]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Ebert L.,
Schick M.,
Neubert P.,
Schatten R.,
Henze S.,
Korn B.;
"Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201).";
Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
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[7]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND VARIANTS SER-72 AND MET-158.
Rieder M.J.,
Livingston R.J.,
Daniels M.R.,
Chung M.-W.,
Miyamoto K.E.,
Nguyen C.P.,
Nguyen D.A.,
Poel C.L.,
Robertson P.D.,
Schackwitz W.S.,
Sherwood J.K.,
Witrak L.A.,
Nickerson D.A.;
"NIEHS-SNPs, environmental genome project, NIEHS ES15478, Department of Genome Sciences, Seattle, WA (URL: http://egp.gs.washington.edu).";
Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases.
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[8]
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NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND VARIANT MET-158.
Mural R.J.,
Istrail S.,
Sutton G.G.,
Florea L.,
Halpern A.L.,
Mobarry C.M.,
Lippert R.,
Walenz B.,
Shatkay H.,
Dew I.,
Miller J.R.,
Flanigan M.J.,
Edwards N.J.,
Bolanos R.,
Fasulo D.,
Halldorsson B.V.,
Hannenhalli S.,
Turner R.,
Yooseph S., ![]()
Lu F.,
Nusskern D.R.,
Shue B.C.,
Zheng X.H.,
Zhong F.,
Delcher A.L.,
Huson D.H.,
Kravitz S.A.,
Mouchard L.,
Reinert K.,
Remington K.A.,
Clark A.G.,
Waterman M.S.,
Eichler E.E.,
Adams M.D.,
Hunkapiller M.W.,
Myers E.W.,
Venter J.C.;
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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[9]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
TISSUE=Brain, and Skin;
DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan]
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
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[10]
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PROTEIN SEQUENCE OF 52-61, AND MASS SPECTROMETRY.
PubMed=8020475 [NCBI, ExPASy, EBI, Israel, Japan]
Vilbois F.,
Caspers P.,
da Prada M.,
Lang G.,
Karrer C.,
Lahm H.W.,
Cesura A.M.;
"Mass spectrometric analysis of human soluble catechol O-methyltransferase expressed in Escherichia coli. Identification of a product of ribosomal frameshifting and of reactive cysteines involved in S-adenosyl-L-methionine binding.";
Eur. J. Biochem. 222:377-386(1994).
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[11]
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PARTIAL PROTEIN SEQUENCE OF 59-271.
TISSUE=Placenta;
DOI=10.1016/0006-291X(91)91517-G; PubMed=1993083 [NCBI, ExPASy, EBI, Israel, Japan]
Tilgmann C.,
Kalkkinen N.;
"Purification and partial sequence analysis of the soluble catechol-O-methyltransferase from human placenta: comparison to the rat liver enzyme.";
Biochem. Biophys. Res. Commun. 174:995-1002(1991).
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[12]
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CHARACTERIZATION OF THE TWO FORMS.
PubMed=1765063 [NCBI, ExPASy, EBI, Israel, Japan]
Ulmanen I.,
Lundstroem K.;
"Cell-free synthesis of rat and human catechol O-methyltransferase. Insertion of the membrane-bound form into microsomal membranes in vitro.";
Eur. J. Biochem. 202:1013-1020(1991).
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[13]
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X-RAY CRYSTALLOGRAPHY (1.3 ANGSTROMS) OF 52-264 OF MUTANTS VAL-108 AND MET-108 IN COMPLEX WITH SUBSTRATE ANALOG 3,5-DINITROCATECHOL; MAGNESIUM AND S-ADENOSYL-L-METHIONINE.
DOI=10.1016/j.jmb.2008.04.040; PubMed=18486144 [NCBI, ExPASy, EBI, Israel, Japan]
Rutherford K.,
Le Trong I.,
Stenkamp R.E.,
Parson W.W.;
"Crystal structures of human 108V and 108M catechol O-methyltransferase.";
J. Mol. Biol. 380:120-130(2008).
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[14]
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VARIANT COMT*2 MET-158.
PubMed=8807664 [NCBI, ExPASy, EBI, Israel, Japan]
Lachman H.M.,
Papolos D.F.,
Saito T.,
Yu Y.-M.,
Szumlanski C.L.,
Weinshilboum R.M.;
"Human catechol-O-methyltransferase pharmacogenetics: description of a functional polymorphism and its potential application to neuropsychiatric disorders.";
Pharmacogenetics 6:243-250(1996).
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[15]
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INVOLVEMENT IN SUSCEPTIBILITY TO ALCOHOLISM.
DOI=10.1038/sj.mp.4000509; PubMed=10395222 [NCBI, ExPASy, EBI, Israel, Japan]
Tiihonen J.,
Hallikainen T.,
Lachman H.,
Saito T.,
Volavka J.,
Kauhanen J.,
Salonen J.T.,
Ryynaenen O.-P.,
Koulu M.,
Karvonen M.K.,
Pohjalainen T.,
Syvaelahti E.,
Hietala J.;
"Association between the functional variant of the catechol-O-methyltransferase (COMT) gene and type 1 alcoholism.";
Mol. Psychiatry 4:286-289(1999).
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[16]
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VARIANTS SER-34 AND SER-72.
DOI=10.1038/10290; PubMed=10391209 [NCBI, ExPASy, EBI, Israel, Japan]
Cargill M.,
Altshuler D.,
Ireland J.,
Sklar P.,
Ardlie K.,
Patil N.,
Shaw N.,
Lane C.R.,
Lim E.P.,
Kalyanaraman N.,
Nemesh J.,
Ziaugra L.,
Friedland L.,
Rolfe A.,
Warrington J.,
Lipshutz R.,
Daley G.Q.,
Lander E.S.;
"Characterization of single-nucleotide polymorphisms in coding regions of human genes.";
Nat. Genet. 22:231-238(1999).
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[17]
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ERRATUM.
Cargill M.,
Altshuler D.,
Ireland J.,
Sklar P.,
Ardlie K.,
Patil N.,
Shaw N.,
Lane C.R.,
Lim E.P.,
Kalyanaraman N.,
Nemesh J.,
Ziaugra L.,
Friedland L.,
Rolfe A.,
Warrington J.,
Lipshutz R.,
Daley G.Q.,
Lander E.S.;
Nat. Genet. 23:373-373(1999).
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[18]
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CHARACTERIZATION OF VARIANT SER-72, AND POSSIBLE INVOLVEMENT IN SCHIZOPHRENIA.
DOI=10.1007/s00439-004-1239-y; PubMed=15645182 [NCBI, ExPASy, EBI, Israel, Japan]
Lee S.-G.,
Joo Y.,
Kim B.,
Chung S.,
Kim H.-L.,
Lee I.,
Choi B.,
Kim C.,
Song K.;
"Association of Ala72Ser polymorphism with COMT enzyme activity and the risk of schizophrenia in Koreans.";
Hum. Genet. 116:319-328(2005).
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[19]
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CHARACTERIZATION OF VARIANT COMT*2 MET-158.
DOI=10.1016/j.bbapap.2008.04.006; PubMed=18474266 [NCBI, ExPASy, EBI, Israel, Japan]
Rutherford K.,
Alphandery E.,
McMillan A.,
Daggett V.,
Parson W.W.;
"The V108M mutation decreases the structural stability of catechol O-methyltransferase.";
Biochim. Biophys. Acta 1784:1098-1105(2008).
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[20]
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VARIANT COMT*2 MET-158.
DOI=10.1016/j.metabol.2008.01.012; PubMed=18442637 [NCBI, ExPASy, EBI, Israel, Japan]
Annerbrink K.,
Westberg L.,
Nilsson S.,
Rosmond R.,
Holm G.,
Eriksson E.;
"Catechol O-methyltransferase val158-met polymorphism is associated with abdominal obesity and blood pressure in men.";
Metabolism 57:708-711(2008).
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