ID ANFC_CHICK Reviewed; 22 AA. AC P21805; DT 01-MAY-1991, integrated into UniProtKB/Swiss-Prot. DT 01-MAY-1991, sequence version 1. DT 22-JUL-2008, entry version 47. DE RecName: Full=C-type natriuretic peptide; DE Short=CNP; GN Name=NPPC; OS Gallus gallus (Chicken). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; OC Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus. OX NCBI_TaxID=9031; RN [1] RP PROTEIN SEQUENCE. RC TISSUE=Brain; RX MEDLINE=91113186; PubMed=1989595; DOI=10.1016/0006-291X(91)90497-U; RA Arimura J.J., Minamino N., Kangawa K., Matsuo H.; RT "Isolation and identification of C-type natriuretic peptide in chicken RT brain."; RL Biochem. Biophys. Res. Commun. 174:142-148(1991). CC -!- FUNCTION: Vasorelaxant activity. Has a cGMP-stimulating activity. CC -!- SUBCELLULAR LOCATION: Secreted. CC -!- SIMILARITY: Belongs to the natriuretic peptide family. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR PIR; JT0581; JT0581. DR UniGene; Gga.12392; -. DR UniGene; Gga.47229; -. DR Ensembl; ENSGALG00000004572; Gallus gallus. DR HOGENOM; P21805; -. DR HOVERGEN; P21805; -. DR InterPro; IPR002408; Br__natriurtcpep. DR InterPro; IPR000663; Natr_peptide. DR Pfam; PF00212; ANP; 1. DR PRINTS; PR00712; BNATPEPTIDE. DR PRINTS; PR00710; NATPEPTIDES. DR ProDom; PD005617; Natr_peptide; 1. DR SMART; SM00183; NAT_PEP; 1. DR PROSITE; PS00263; NATRIURETIC_PEPTIDE; 1. PE 1: Evidence at protein level; KW Direct protein sequencing; Hormone; Secreted; Vasoactive. FT PEPTIDE 1 22 C-type natriuretic peptide. FT /FTId=PRO_0000043486. FT DISULFID 6 22 SQ SEQUENCE 22 AA; 2244 MW; FC2A4706D8DAC025 CRC64; GLSRSCFGVK LDRIGSMSGL GC //