[1]	PROTEIN SEQUENCE. PubMed=1830879 [NCBI, ExPASy, EBI, Israel, Japan] Xu J., Oshima T., Yoshida M.; "Phosphoenolpyruvate-insensitive phosphofructokinase isozyme from Thermus thermophilus HB8."; J. Biochem. 109:199-203(1991).

Comments

CATALYTIC ACTIVITY: ATP + D-fructose 6-phosphate = ADP + D-fructose 1,6-bisphosphate.
ENZYME REGULATION: In contrast with PFK1 this enzyme is not affected by phosphoenolpyruvate.
PATHWAY: Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4 .
SUBUNIT: Homotetramer.
SUBCELLULAR LOCATION: Cytoplasm.
SIMILARITY: Belongs to the phosphofructokinase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

3D structure databases

Ontologies

GO:0005945;	Cellular component: 6-phosphofructokinase complex (inferred from electronic annotation from InterPro).
GO:0003872;	Molecular function: 6-phosphofructokinase activity (inferred from electronic annotation from HAMAP).
GO:0005524;	Molecular function: ATP binding (inferred from electronic annotation from UniProtKB-KW).
GO:0006096;	Biological process: glycolysis (inferred from electronic annotation from HAMAP).
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Family and domain databases

MF_00339; -; 1.
PBIL [Tree]

PS00433; PHOSPHOFRUCTOKINASE; PARTIAL.

Other

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

ATP-binding; Cytoplasm; Direct protein sequencing; Glycolysis; Kinase; Nucleotide-binding; Transferase.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 >25`	`>25`	`6-phosphofructokinase isozyme 2.`	`PRO_0000112002`
`NP_BIND`	`21 25`	`5`	`ATP (By similarity).`
`NON_TER`	`25 25`

Sequence information

Length: 25 AA [This is the length of the partial sequence of the unprocessed precursor]

Molecular weight: 2557 Da [This is the MW of the partial sequence of the unprocessed precursor]

CRC64: E7AEC8D6110EBA46 [This is a checksum on the sequence]

        10         20 
MKRIGVLTSG GDSPGMNAAI RAVVR

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools