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UniProtKB/Swiss-Prot entry P21577

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name 6PGD_SYNE7
Primary accession number P21577
Secondary accession number Q31S98
Integrated into Swiss-Prot on May 1, 1991
Sequence was last modified on April 18, 2006 (Sequence version 4)
Annotations were last modified on    July 22, 2008 (Entry version 59)
Name and origin of the protein
Protein name 6-phosphogluconate dehydrogenase, decarboxylating
Synonym EC 1.1.1.44
Gene name
Name: gnd
OrderedLocusNames: Synpcc7942_0039
From
Synechococcus elongatus (strain PCC 7942) (Anacystis nidulans R2) [TaxID: 1140] [HAMAP proteome]
Taxonomy Bacteria; Cyanobacteria; Chroococcales; Synechococcus.
Protein existence 1: Evidence at protein level;
References
[1]
 NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND SUBSTRATE-BINDING SITE.
PubMed=2113917 [NCBI, ExPASy, EBI, Israel, Japan]
Broedel S.E. Jr., Wolf R.E. Jr.;
"Genetic tagging, cloning, and DNA sequence of the Synechococcus sp. strain PCC 7942 gene (gnd) encoding 6-phosphogluconate dehydrogenase.";
J. Bacteriol. 172:4023-4031(1990).
[2]
 NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Culler D.C., Krogmann D.W.;
"Amino acid sequence comparisons of 6-phosphogluconate dehydrogenase.";
Submitted (APR-1991) to the EMBL/GenBank/DDBJ databases.
[3]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Schmutz J., Larimer F., Land M., Kyrpides N., Lykidis A., Richardson P.;
"Complete sequence of chromosome 1 of Synechococcus elongatus PCC 7942.";
Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
M55002; AAA27330.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
X58719; CAA41555.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
CP000100; ABB56071.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR S14628; S14628.
RefSeq YP_399058.1; -.
3D structure databases
HSSP P00349; 2PGD. [HSSP ENTRY / PDB]
ModBase P21577.
Enzyme and pathway databases
BioCyc SELO1140:SYNPCC7942_0039-MON; -.
Family and domain databases
InterPro IPR006183; 6-phosphogluconate_DHase.
IPR006114; 6PGDH_C.
IPR006113; 6PGDH_decarbox.
IPR006115; 6PGDH_NAD-bd.
IPR006184; 6PGdom_BS.
IPR013328; DHase_multihelical.
IPR012284; Fibritin/6PGD_C-extension.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:1.20.5.320; Fibritin/6PGD_C-extension; 1.
G3DSA:3.40.50.720; NAD(P)-bd; 1.
G3DSA:1.10.1040.10; Opine_DH; 1.
Pfam PF00393; 6PGD; 1.
PF03446; NAD_binding_2; 1.
Pfam graphical view of domain structure.
PRINTS PR00076; 6PGDHDRGNASE.
TIGRFAMs TIGR00873; gnd; 1.
PROSITE PS00461; 6PGD; 1.
BLOCKS P21577.
Genome annotation databases
GeneID 3775852; -.
GenomeReviews CP000100_GR; Synpcc7942_0039.
KEGG syf:Synpcc7942_0039; -.
Phylogenomic databases
HOGENOM P21577; -.
Genome annotation databases
CMR P21577; Synpcc7942_0039.
Other
ProtoNet P21577.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Gluconate utilization; NADP; Oxidoreductase; Pentose shunt.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   471  471     6-phosphogluconate dehydrogenase, decarboxylating. PRO_0000090060
CONFLICT   154   159        EPIVRS -> SRSVPT (in Ref. 1; AAA27330). 
CONFLICT   159   159        S -> T (in Ref. 2; CAA41555). 
CONFLICT   407   407        A -> R (in Ref. 2; CAA41555). 
CONFLICT   415   439        AAERGIPVPAFSASLDYFDSYRRDR -> RQNEEFRFRFQCFPGLLRQLPARS (in Ref. 2; CAA41555). 
CONFLICT   437   441        RDRLP -> ASPA (in Ref. 1; AAA27330). 
CONFLICT   450   453        DYFG -> TTC (in Ref. 1). 
CONFLICT   458   465        ERTDRSGS -> KAPIALL (in Ref. 1; AAA27330). 
CONFLICT   469   470        QW -> M (in Ref. 1). 
Sequence information
Length: 471 AA [This is the length of the unprocessed precursor] Molecular weight: 51073 Da [This is the MW of the unprocessed precursor] CRC64: 0C75D58209E124E7 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MALQQFGLIG LAVMGENLAL NIERNGFSLT VYNRTAEKTE AFMADRAQGK NIVPAYSLED 

        70         80         90        100        110        120 
FVASLERPRR ILVMVKAGGP VDAVVEQLKP LLDPGDLIID GGNSLFTDTE RRVKDLEALG 

       130        140        150        160        170        180 
LGFMGMGVSG GEEGALNGPS LMPGGTQAAY EAVEPIVRSI AAQVDDGPCV TYIGPGGSGH 

       190        200        210        220        230        240 
YVKMVHNGIE YGDMQLIAEA YDLLKSVAGL NASELHDVFA AWNKTPELDS FLIEITADIF 

       250        260        270        280        290        300 
TKVDDLGTGQ PLVELILDAA GQKGTGRWTV ETALEIGVAI PTIIAAVNAR ILSSIKAERQ 

       310        320        330        340        350        360 
AASEILSGPI TEPFSGDRQA FIDSVRDALY CSKICSYAQG MALLAKASQV YNYGLNLGEL 

       370        380        390        400        410        420 
ARIWKGGCII RAGFLNKIKQ AYDADPTLAN LLLAPEFRQT ILDRQLAWRR VIAIAAERGI 

       430        440        450        460        470 
PVPAFSASLD YFDSYRRDRL PQNLTQAQRD YFGAHTYERT DRSGSFHAQW F
P21577 in FASTA format

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