[1]
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NUCLEOTIDE SEQUENCE [MRNA].
TISSUE=Placenta;
DOI=10.1073/pnas.87.7.2735; PubMed=2157211 [NCBI, ExPASy, EBI, Israel, Japan]
Chernoff J.,
Schievella A.R.,
Jost C.A.,
Erikson R.L.,
Neel B.G.;
"Cloning of a cDNA for a major human protein-tyrosine-phosphatase.";
Proc. Natl. Acad. Sci. U.S.A. 87:2735-2739(1990).
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[2]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
TISSUE=Placenta;
DOI=10.1073/pnas.87.13.5148; PubMed=2164224 [NCBI, ExPASy, EBI, Israel, Japan]
Brown-Shimer S.,
Johnson K.A.,
Lawrence J.B.,
Johnson C.,
Bruskin A.,
Green N.R.,
Hill D.E.;
"Molecular cloning and chromosome mapping of the human gene encoding protein phosphotyrosyl phosphatase 1B.";
Proc. Natl. Acad. Sci. U.S.A. 87:5148-5152(1990).
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[3]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Kalnine N.,
Chen X.,
Rolfs A.,
Halleck A.,
Hines L.,
Eisenstein S.,
Koundinya M.,
Raphael J.,
Moreira D.,
Kelley T.,
LaBaer J.,
Lin Y.,
Phelan M.,
Farmer A.;
"Cloning of human full-length CDSs in BD Creator(TM) system donor vector.";
Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
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[4]
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NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1038/414865a; PubMed=11780052 [NCBI, ExPASy, EBI, Israel, Japan]
Deloukas P.,
Matthews L.H.,
Ashurst J.L.,
Burton J.,
Gilbert J.G.R.,
Jones M.,
Stavrides G.,
Almeida J.P.,
Babbage A.K.,
Bagguley C.L.,
Bailey J.,
Barlow K.F.,
Bates K.N.,
Beard L.M.,
Beare D.M.,
Beasley O.P.,
Bird C.P.,
Blakey S.E.,
Bridgeman A.M., ![]()
Brown A.J.,
Buck D.,
Burrill W.D.,
Butler A.P.,
Carder C.,
Carter N.P.,
Chapman J.C.,
Clamp M.,
Clark G.,
Clark L.N.,
Clark S.Y.,
Clee C.M.,
Clegg S.,
Cobley V.E.,
Collier R.E.,
Connor R.E.,
Corby N.R.,
Coulson A.,
Coville G.J.,
Deadman R.,
Dhami P.D.,
Dunn M.,
Ellington A.G.,
Frankland J.A.,
Fraser A.,
French L.,
Garner P.,
Grafham D.V.,
Griffiths C.,
Griffiths M.N.D.,
Gwilliam R.,
Hall R.E.,
Hammond S.,
Harley J.L.,
Heath P.D.,
Ho S.,
Holden J.L.,
Howden P.J.,
Huckle E.,
Hunt A.R.,
Hunt S.E.,
Jekosch K.,
Johnson C.M.,
Johnson D.,
Kay M.P.,
Kimberley A.M.,
King A.,
Knights A.,
Laird G.K.,
Lawlor S.,
Lehvaeslaiho M.H.,
Leversha M.A.,
Lloyd C.,
Lloyd D.M.,
Lovell J.D.,
Marsh V.L.,
Martin S.L.,
McConnachie L.J.,
McLay K.,
McMurray A.A.,
Milne S.A.,
Mistry D.,
Moore M.J.F.,
Mullikin J.C.,
Nickerson T.,
Oliver K.,
Parker A.,
Patel R.,
Pearce T.A.V.,
Peck A.I.,
Phillimore B.J.C.T.,
Prathalingam S.R.,
Plumb R.W.,
Ramsay H.,
Rice C.M.,
Ross M.T.,
Scott C.E.,
Sehra H.K.,
Shownkeen R.,
Sims S.,
Skuce C.D.,
Smith M.L.,
Soderlund C.,
Steward C.A.,
Sulston J.E.,
Swann R.M.,
Sycamore N.,
Taylor R.,
Tee L.,
Thomas D.W.,
Thorpe A.,
Tracey A.,
Tromans A.C.,
Vaudin M.,
Wall M.,
Wallis J.M.,
Whitehead S.L.,
Whittaker P.,
Willey D.L.,
Williams L.,
Williams S.A.,
Wilming L.,
Wray P.W.,
Hubbard T.,
Durbin R.M.,
Bentley D.R.,
Beck S.,
Rogers J.;
"The DNA sequence and comparative analysis of human chromosome 20.";
Nature 414:865-871(2001).
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[5]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
TISSUE=Eye, and Lymph;
DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan]
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
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[6]
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PROTEIN SEQUENCE OF 1-321.
TISSUE=Placenta;
DOI=10.1073/pnas.86.14.5252; PubMed=2546149 [NCBI, ExPASy, EBI, Israel, Japan]
Charbonneau H.,
Tonks N.K.,
Kumar S.,
Diltz C.D.,
Harrylock M.,
Cool D.E.,
Krebs E.G.,
Fischer E.H.,
Walsh K.A.;
"Human placenta protein-tyrosine-phosphatase: amino acid sequence and relationship to a family of receptor-like proteins.";
Proc. Natl. Acad. Sci. U.S.A. 86:5252-5256(1989).
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[7]
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PHOSPHORYLATION AT SER-352; SER-378 AND SER-386.
PubMed=8491187 [NCBI, ExPASy, EBI, Israel, Japan]
Flint A.J.,
Gebbink M.F.G.B.,
Franza B.R. Jr.,
Hill D.E.,
Tonks N.K.;
"Multi-site phosphorylation of the protein tyrosine phosphatase, PTP1B: identification of cell cycle regulated and phorbol ester stimulated sites of phosphorylation.";
EMBO J. 12:1937-1946(1993).
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[8]
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SUBCELLULAR LOCATION.
DOI=10.1016/0092-8674(92)90190-N; PubMed=1739967 [NCBI, ExPASy, EBI, Israel, Japan]
Frangioni J.V.,
Beahm P.H.,
Shifrin V.,
Jost C.A.,
Neel B.G.;
"The nontransmembrane tyrosine phosphatase PTP-1B localizes to the endoplasmic reticulum via its 35 amino acid C-terminal sequence.";
Cell 68:545-560(1992).
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[9]
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PHOSPHORYLATION AT SER-50, AND MUTAGENESIS OF SER-50.
DOI=10.1210/me.15.10.1768; PubMed=11579209 [NCBI, ExPASy, EBI, Israel, Japan]
Ravichandran L.V.,
Chen H.,
Li Y.,
Quon M.J.;
"Phosphorylation of PTP1B at Ser(50) by Akt impairs its ability to dephosphorylate the insulin receptor.";
Mol. Endocrinol. 15:1768-1780(2001).
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[10]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-20, AND MASS SPECTROMETRY.
DOI=10.1038/nbt1046; PubMed=15592455 [NCBI, ExPASy, EBI, Israel, Japan]
Rush J.,
Moritz A.,
Lee K.A.,
Guo A.,
Goss V.L.,
Spek E.J.,
Zhang H.,
Zha X.-M.,
Polakiewicz R.D.,
Comb M.J.;
"Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.";
Nat. Biotechnol. 23:94-101(2005).
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[11]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-50 AND SER-295, AND MASS SPECTROMETRY.
TISSUE=Epithelium;
DOI=10.1016/j.cell.2006.09.026; PubMed=17081983 [NCBI, ExPASy, EBI, Israel, Japan]
Olsen J.V.,
Blagoev B.,
Gnad F.,
Macek B.,
Kumar C.,
Mortensen P.,
Mann M.;
"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.";
Cell 127:635-648(2006).
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[12]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-50 AND SER-352, AND MASS SPECTROMETRY.
DOI=10.1016/j.molcel.2008.07.007; PubMed=18691976 [NCBI, ExPASy, EBI, Israel, Japan]
Daub H.,
Olsen J.V.,
Bairlein M.,
Gnad F.,
Oppermann F.S.,
Korner R.,
Greff Z.,
Keri G.,
Stemmann O.,
Mann M.;
"Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.";
Mol. Cell 31:438-448(2008).
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[13]
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IDENTIFICATION [LARGE SCALE ANALYSIS], AND MASS SPECTROMETRY.
Colinge J.,
Superti-Furga G.,
Bennett K.L.;
Submitted (OCT-2008) to UniProtKB.
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[14]
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X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS) OF 1-321.
DOI=10.1126/science.8128219; PubMed=8128219 [NCBI, ExPASy, EBI, Israel, Japan]
Barford D.,
Flint A.J.,
Tonks N.K.;
"Crystal structure of human protein tyrosine phosphatase 1B.";
Science 263:1397-1404(1994).
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[15]
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X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) OF 1-298 OF MUTANT SER-215.
DOI=10.1073/pnas.94.25.13420; PubMed=9391040 [NCBI, ExPASy, EBI, Israel, Japan]
Puius Y.A.,
Zhao Y.,
Sullivan M.,
Lawrence D.S.,
Almo S.C.,
Zhang Z.Y.;
"Identification of a second aryl phosphate-binding site in protein-tyrosine phosphatase 1B: a paradigm for inhibitor design.";
Proc. Natl. Acad. Sci. U.S.A. 94:13420-13425(1997).
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[16]
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X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS) OF 1-285.
DOI=10.1074/jbc.273.17.10454; PubMed=9553104 [NCBI, ExPASy, EBI, Israel, Japan]
Pannifer A.D.,
Flint A.J.,
Tonks N.K.,
Barford D.;
"Visualization of the cysteinyl-phosphate intermediate of a protein-tyrosine phosphatase by X-ray crystallography.";
J. Biol. Chem. 273:10454-10462(1998).
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[17]
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X-RAY CRYSTALLOGRAPHY (2.35 ANGSTROMS) OF 1-298.
DOI=10.1021/bi9816958; PubMed=9922143 [NCBI, ExPASy, EBI, Israel, Japan]
Groves M.R.,
Yao Z.-J.,
Roller P.P.,
Burke T.R. Jr.,
Barford D.;
"Structural basis for inhibition of the protein tyrosine phosphatase 1B by phosphotyrosine peptide mimetics.";
Biochemistry 37:17773-17783(1998).
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[18]
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X-RAY CRYSTALLOGRAPHY (1.8 ANGSTROMS) OF 1-321, OXIDATION AT CYS-215, AND CROSS-LINK 215-CYS-SER-216.
DOI=10.1038/nature01680; PubMed=12802338 [NCBI, ExPASy, EBI, Israel, Japan]
Salmeen A.,
Andersen J.N.,
Myers M.P.,
Meng T.-C.,
Hinks J.A.,
Tonks N.K.,
Barford D.;
"Redox regulation of protein tyrosine phosphatase 1B involves a sulphenyl-amide intermediate.";
Nature 423:769-773(2003).
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[19]
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X-RAY CRYSTALLOGRAPHY (2.2 ANGSTROMS) OF 1-321, OXIDATION AT CYS-215, AND CROSS-LINK 215-CYS-SER-216.
DOI=10.1038/nature01681; PubMed=12802339 [NCBI, ExPASy, EBI, Israel, Japan]
Van Montfort R.L.M.,
Congreve M.,
Tisi D.,
Carr R.,
Jhoti H.;
"Oxidation state of the active-site cysteine in protein tyrosine phosphatase 1B.";
Nature 423:773-777(2003).
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[20]
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ASSOCIATION OF VARIANT LEU-387 WITH LOW GLUCOSE TOLERANCE.
DOI=10.1038/oby.2005.95; PubMed=15919835 [NCBI, ExPASy, EBI, Israel, Japan]
Ukkola O.,
Rankinen T.,
Lakka T.,
Leon A.S.,
Skinner J.S.,
Wilmore J.H.,
Rao D.C.,
Kesaeniemi Y.A.,
Bouchard C.;
"Protein tyrosine phosphatase 1B variant associated with fat distribution and insulin metabolism.";
Obes. Res. 13:829-834(2005).
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