[1]
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NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM FLT1).
TISSUE=Placenta;
PubMed=2158038 [NCBI, ExPASy, EBI, Israel, Japan]
Shibuya M.,
Yamaguchi S.,
Yamane A.,
Ikeda T.,
Tojo A.,
Matsushime H.,
Sato M.;
"Nucleotide sequence and expression of a novel human receptor-type tyrosine kinase gene (flt) closely related to the fms family.";
Oncogene 5:519-524(1990).
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[2]
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NUCLEOTIDE SEQUENCE (ISOFORM FLT1).
TISSUE=Umbilical vein;
Yu Y.,
Whitney R.G.,
Sato J.D.;
"Coding region for human VEGF receptor FLT1 (VEGFR-1).";
Submitted (MAY-1998) to the EMBL/GenBank/DDBJ databases.
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[3]
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NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM SFLT1), AND PROTEIN SEQUENCE OF N-TERMINUS.
TISSUE=Umbilical vein;
DOI=10.1073/pnas.90.22.10705; PubMed=8248162 [NCBI, ExPASy, EBI, Israel, Japan]
Kendall R.L.,
Thomas K.A.;
"Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor.";
Proc. Natl. Acad. Sci. U.S.A. 90:10705-10709(1993).
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[4]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM SFLT1).
TISSUE=Ovary;
DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan]
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
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[5]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1018-1058 (ISOFORM FLT1).
PubMed=3040650 [NCBI, ExPASy, EBI, Israel, Japan]
Matsushime H.,
Yoshida M.C.,
Sasaki M.,
Shibuya M.;
"A possible new member of tyrosine kinase family, human frt sequence, is highly conserved in vertebrates and located on human chromosome 13.";
Jpn. J. Cancer Res. 78:655-661(1987).
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[6]
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PARTIAL PROTEIN SEQUENCE, PHOSPHORYLATION AT TYR-1213; TYR-1242; TYR-1327 AND TYR-1333, AND MUTAGENESIS OF TYR-914; TYR-1213; TYR-1242; TYR-1327 AND TYR-1333.
DOI=10.1074/jbc.273.36.23410; PubMed=9722576 [NCBI, ExPASy, EBI, Israel, Japan]
Ito N.,
Wernstedt C.,
Engstrom U.,
Claesson-Welsh L.;
"Identification of vascular endothelial growth factor receptor-1 tyrosine phosphorylation sites and binding of SH2 domain-containing molecules.";
J. Biol. Chem. 273:23410-23418(1998).
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[7]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-1048 AND TYR-1053, AND MASS SPECTROMETRY.
DOI=10.1016/j.cell.2007.11.025; PubMed=18083107 [NCBI, ExPASy, EBI, Israel, Japan]
Rikova K.,
Guo A.,
Zeng Q.,
Possemato A.,
Yu J.,
Haack H.,
Nardone J.,
Lee K.,
Reeves C.,
Li Y.,
Hu Y.,
Tan Z.,
Stokes M.,
Sullivan L.,
Mitchell J.,
Wetzel R.,
Macneill J.,
Ren J.M.,
Yuan J., ![]()
Bakalarski C.E.,
Villen J.,
Kornhauser J.M.,
Smith B.,
Li D.,
Zhou X.,
Gygi S.P.,
Gu T.-L.,
Polakiewicz R.D.,
Rush J.,
Comb M.J.;
"Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer.";
Cell 131:1190-1203(2007).
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[8]
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STRUCTURE BY NMR OF 129-229.
DOI=10.1006/jmbi.1999.3134; PubMed=10543948 [NCBI, ExPASy, EBI, Israel, Japan]
Starovasnik M.A.,
Christinger H.W.,
Wiesmann C.,
Champe M.A.,
de Vos A.M.,
Skelton N.J.;
"Solution structure of the VEGF-binding domain of Flt-1: comparison of its free and bound states.";
J. Mol. Biol. 293:531-544(1999).
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[9]
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VARIANTS [LARGE SCALE ANALYSIS] THR-60; LYS-144; GLN-281; ILE-422; GLN-781; VAL-938; ALA-982 AND VAL-1061.
DOI=10.1038/nature05610; PubMed=17344846 [NCBI, ExPASy, EBI, Israel, Japan]
Greenman C.,
Stephens P.,
Smith R.,
Dalgliesh G.L.,
Hunter C.,
Bignell G.,
Davies H.,
Teague J.,
Butler A.,
Stevens C.,
Edkins S.,
O'Meara S.,
Vastrik I.,
Schmidt E.E.,
Avis T.,
Barthorpe S.,
Bhamra G.,
Buck G.,
Choudhury B., ![]()
Clements J.,
Cole J.,
Dicks E.,
Forbes S.,
Gray K.,
Halliday K.,
Harrison R.,
Hills K.,
Hinton J.,
Jenkinson A.,
Jones D.,
Menzies A.,
Mironenko T.,
Perry J.,
Raine K.,
Richardson D.,
Shepherd R.,
Small A.,
Tofts C.,
Varian J.,
Webb T.,
West S.,
Widaa S.,
Yates A.,
Cahill D.P.,
Louis D.N.,
Goldstraw P.,
Nicholson A.G.,
Brasseur F.,
Looijenga L.,
Weber B.L.,
Chiew Y.-E.,
DeFazio A.,
Greaves M.F.,
Green A.R.,
Campbell P.,
Birney E.,
Easton D.F.,
Chenevix-Trench G.,
Tan M.-H.,
Khoo S.K.,
Teh B.T.,
Yuen S.T.,
Leung S.Y.,
Wooster R.,
Futreal P.A.,
Stratton M.R.;
"Patterns of somatic mutation in human cancer genomes.";
Nature 446:153-158(2007).
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