[1]
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NUCLEOTIDE SEQUENCE [MRNA].
TISSUE=Blood;
DOI=10.1093/nar/18.8.2183; PubMed=2336401 [NCBI, ExPASy, EBI, Israel, Japan]
Finkenzeller G.,
Marme D.,
Hug H.;
"Sequence of human protein kinase C alpha.";
Nucleic Acids Res. 18:2183-2183(1990).
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[2]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan]
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
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[3]
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NUCLEOTIDE SEQUENCE [MRNA] OF 15-445.
PubMed=1714454 [NCBI, ExPASy, EBI, Israel, Japan]
McSwine-Kennick R.L.,
McKeegan E.M.,
Johnson M.D.,
Morin M.J.;
"Phorbol diester-induced alterations in the expression of protein kinase C isozymes and their mRNAs. Analysis in wild-type and phorbol diester-resistant HL-60 cell clones.";
J. Biol. Chem. 266:15135-15143(1991).
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[4]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-57.
Haridasse V.,
Hackenbruck J.,
Glazer R.I.;
"Homo sapiens protein kinase C alpha 5-flanking sequence.";
Submitted (JUN-2001) to the EMBL/GenBank/DDBJ databases.
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[5]
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PROTEIN SEQUENCE OF 2-19.
TISSUE=Platelet;
DOI=10.1038/nbt810; PubMed=12665801 [NCBI, ExPASy, EBI, Israel, Japan]
Gevaert K.,
Goethals M.,
Martens L.,
Van Damme J.,
Staes A.,
Thomas G.R.,
Vandekerckhove J.;
"Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.";
Nat. Biotechnol. 21:566-569(2003).
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[6]
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INTERACTION WITH ADAP1.
DOI=10.1016/S0006-291X(03)01187-2; PubMed=12893243 [NCBI, ExPASy, EBI, Israel, Japan]
Zemlickova E.,
Dubois T.,
Kerai P.,
Clokie S.,
Cronshaw A.D.,
Wakefield R.I.D.,
Johannes F.-J.,
Aitken A.;
"Centaurin-alpha(1) associates with and is phosphorylated by isoforms of protein kinase C.";
Biochem. Biophys. Res. Commun. 307:459-465(2003).
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[7]
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FUNCTION IN PHOSPHORYLATION OF CSPG4, AND INTERACTION WITH CSPG4.
DOI=10.1074/jbc.M411045200; PubMed=15504744 [NCBI, ExPASy, EBI, Israel, Japan]
Makagiansar I.T.,
Williams S.,
Dahlin-Huppe K.,
Fukushi J.,
Mustelin T.,
Stallcup W.B.;
"Phosphorylation of NG2 proteoglycan by protein kinase C-alpha regulates polarized membrane distribution and cell motility.";
J. Biol. Chem. 279:55262-55270(2004).
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[8]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-226 AND SER-319, AND MASS SPECTROMETRY.
TISSUE=Epithelium;
DOI=10.1016/j.cell.2006.09.026; PubMed=17081983 [NCBI, ExPASy, EBI, Israel, Japan]
Olsen J.V.,
Blagoev B.,
Gnad F.,
Macek B.,
Kumar C.,
Mortensen P.,
Mann M.;
"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.";
Cell 127:635-648(2006).
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[9]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-319, AND MASS SPECTROMETRY.
TISSUE=Epithelium;
DOI=10.1038/nbt1240; PubMed=16964243 [NCBI, ExPASy, EBI, Israel, Japan]
Beausoleil S.A.,
Villen J.,
Gerber S.A.,
Rush J.,
Gygi S.P.;
"A probability-based approach for high-throughput protein phosphorylation analysis and site localization.";
Nat. Biotechnol. 24:1285-1292(2006).
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[10]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-195, AND MASS SPECTROMETRY.
TISSUE=Lung;
DOI=10.1016/j.cell.2007.11.025; PubMed=18083107 [NCBI, ExPASy, EBI, Israel, Japan]
Rikova K.,
Guo A.,
Zeng Q.,
Possemato A.,
Yu J.,
Haack H.,
Nardone J.,
Lee K.,
Reeves C.,
Li Y.,
Hu Y.,
Tan Z.,
Stokes M.,
Sullivan L.,
Mitchell J.,
Wetzel R.,
Macneill J.,
Ren J.M.,
Yuan J., ![]()
Bakalarski C.E.,
Villen J.,
Kornhauser J.M.,
Smith B.,
Li D.,
Zhou X.,
Gygi S.P.,
Gu T.-L.,
Polakiewicz R.D.,
Rush J.,
Comb M.J.;
"Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer.";
Cell 131:1190-1203(2007).
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[11]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-226; THR-497; THR-501; THR-638 AND TYR-658, AND MASS SPECTROMETRY.
DOI=10.1074/mcp.T600062-MCP200; PubMed=17192257 [NCBI, ExPASy, EBI, Israel, Japan]
Wissing J.,
Jaensch L.,
Nimtz M.,
Dieterich G.,
Hornberger R.,
Keri G.,
Wehland J.,
Daub H.;
"Proteomics analysis of protein kinases by target class-selective prefractionation and tandem mass spectrometry.";
Mol. Cell. Proteomics 6:537-547(2007).
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[12]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-319, AND MASS SPECTROMETRY.
TISSUE=Platelet;
DOI=10.1021/pr0704130; PubMed=18088087 [NCBI, ExPASy, EBI, Israel, Japan]
Zahedi R.P.,
Lewandrowski U.,
Wiesner J.,
Wortelkamp S.,
Moebius J.,
Schuetz C.,
Walter U.,
Gambaryan S.,
Sickmann A.;
"Phosphoproteome of resting human platelets.";
J. Proteome Res. 7:526-534(2008).
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[13]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-208; SER-226; SER-319 AND THR-497, AND MASS SPECTROMETRY.
DOI=10.1016/j.molcel.2008.07.007; PubMed=18691976 [NCBI, ExPASy, EBI, Israel, Japan]
Daub H.,
Olsen J.V.,
Bairlein M.,
Gnad F.,
Oppermann F.S.,
Korner R.,
Greff Z.,
Keri G.,
Stemmann O.,
Mann M.;
"Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.";
Mol. Cell 31:438-448(2008).
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[14]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-226, AND MASS SPECTROMETRY.
DOI=10.1073/pnas.0805139105; PubMed=18669648 [NCBI, ExPASy, EBI, Israel, Japan]
Dephoure N.,
Zhou C.,
Villen J.,
Beausoleil S.A.,
Bakalarski C.E.,
Elledge S.J.,
Gygi S.P.;
"A quantitative atlas of mitotic phosphorylation.";
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
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[15]
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IDENTIFICATION [LARGE SCALE ANALYSIS], AND MASS SPECTROMETRY.
Colinge J.,
Superti-Furga G.,
Bennett K.L.;
Submitted (OCT-2008) to UniProtKB.
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[16]
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STRUCTURE BY NMR OF 88-169.
RIKEN structural genomics initiative (RSGI);
"Solution structure of the second phorbol esters/diacylglycerol binding domain of human protein kinase C alpha type.";
Submitted (APR-2008) to the PDB data bank.
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[17]
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VARIANTS [LARGE SCALE ANALYSIS] SER-98; ASN-467 AND VAL-489.
DOI=10.1038/nature05610; PubMed=17344846 [NCBI, ExPASy, EBI, Israel, Japan]
Greenman C.,
Stephens P.,
Smith R.,
Dalgliesh G.L.,
Hunter C.,
Bignell G.,
Davies H.,
Teague J.,
Butler A.,
Stevens C.,
Edkins S.,
O'Meara S.,
Vastrik I.,
Schmidt E.E.,
Avis T.,
Barthorpe S.,
Bhamra G.,
Buck G.,
Choudhury B., ![]()
Clements J.,
Cole J.,
Dicks E.,
Forbes S.,
Gray K.,
Halliday K.,
Harrison R.,
Hills K.,
Hinton J.,
Jenkinson A.,
Jones D.,
Menzies A.,
Mironenko T.,
Perry J.,
Raine K.,
Richardson D.,
Shepherd R.,
Small A.,
Tofts C.,
Varian J.,
Webb T.,
West S.,
Widaa S.,
Yates A.,
Cahill D.P.,
Louis D.N.,
Goldstraw P.,
Nicholson A.G.,
Brasseur F.,
Looijenga L.,
Weber B.L.,
Chiew Y.-E.,
DeFazio A.,
Greaves M.F.,
Green A.R.,
Campbell P.,
Birney E.,
Easton D.F.,
Chenevix-Trench G.,
Tan M.-H.,
Khoo S.K.,
Teh B.T.,
Yuen S.T.,
Leung S.Y.,
Wooster R.,
Futreal P.A.,
Stratton M.R.;
"Patterns of somatic mutation in human cancer genomes.";
Nature 446:153-158(2007).
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