|
|
|
|
|
|
|
|
|
- FUNCTION: Forms the icosaedric capsid of the virus protecting the viral genome. This capsid is composed of 360 VP1, assembled in 72 pentamers. Each pentamer are linked via the C-terminal end of VP1 (By similarity).
- SUBUNIT: The virus capsid is composed of 75 icosahedral units, each of which is composed of five disulfide-linked copies of VP1 (By similarity).
- SUBCELLULAR LOCATION: Virion. Nucleus (By similarity).
- ALTERNATIVE PRODUCTS:
4 named isoforms [FASTA] produced by alternative splicing and alternative initiation.
|
| Name | VP2 |
| Isoform ID | P14997-1 |
| This isoform is stored in UniProtKB/Swiss-Prot entry P14997. |
|
|
| Name | VP3 |
| Isoform ID | P14997-2 |
| Note: Produced by alternative initiation at Met-120 of isoform VP2. |
| This isoform is stored in UniProtKB/Swiss-Prot entry P14997. |
|
|
| Name | Agno |
| Isoform ID | P14998-1 |
| Note: Produced by alternative initiation of isoform VP1 and VP2. |
| This isoform is stored in UniProtKB/Swiss-Prot entry P14998. |
|
|
- DOMAIN: The intrinsically disordered C-terminal region interacts with neighboring pentamers. The unstructured nature of this region allows to make different interactions depending on the stuctural context: pentamers present at the 12 icosahedral fivefold axes bind five pentamers, when pentamers present at the 60 icosahedral six-fold axes interacts with six pentamers (By similarity).
- SIMILARITY: Belongs to the polyomaviruses coat protein VP1 family.
|
|
|
|
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms.
Distributed under the Creative Commons Attribution-NoDerivs License.
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Length: 362 AA [This is the length of the unprocessed precursor] |
Molecular weight: 40113 Da [This is the MW of the unprocessed precursor] |
CRC64: 5BDCEC52F247F238 [This is a checksum on the sequence] |
|
10 20 30 40 50 60
MAPTKRKGEC PGAAPKKPKE PVQVPKLLIK GGVEVLEVKT GVDAITEVEC FLNPEMGDPD
70 80 90 100 110 120
DNLRGYSQHL SAENAFESDS PDRKMLPCYS TARIPLPNLN EDLTCGNLLM WEAVTVKTEV
130 140 150 160 170 180
IGITSMLNLH AGSQKVHENG GGKPVQGSNF HFFAVGGDPL EMQGVLMNYR TKYPQGTITP
190 200 210 220 230 240
KNPTAQSQVM NTDHKAYLDK NNAYPVECWI PDPSRNENTR YFGTYTGGEN VPPVLHVTNT
250 260 270 280 290 300
ATTVLLDEQG VGPLCKADSL YVSAADICGL FTNSSGTQQW RGLARYFKIR LRKRSVKNPY
310 320 330 340 350 360
PISFLLSDLI NRRTQKVDGQ PMYGMESQVE EVRVFDGTEQ LPGDPDMIRY IDRQGQLQTK
MV
|
P14996 in FASTA format |
|
ExPASy Home page
SIB Switzerland
