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UniProtKB/Swiss-Prot entry P13202


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name VIE1_HCMVA
Primary accession number P13202
Secondary accession number Q7M6S4
Integrated into Swiss-Prot on January 1, 1990
Sequence was last modified on January 1, 1990 (Sequence version 1)
Annotations were last modified on    June 16, 2009 (Entry version 40)
Name and origin of the protein
Protein name 55 kDa immediate-early protein 1
Synonym IE1
Gene name
Name: UL123
From
Human cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5) [TaxID: 10360] 
Taxonomy Viruses; dsDNA viruses, no RNA stage; Herpesvirales; Herpesviridae; Betaherpesvirinae; Cytomegalovirus.
Virus host Homo sapiens (Human) [TaxID: 9606]
Protein existence 4: Predicted;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
DOI=10.1016/0168-1702(85)90242-4; PubMed=2986374 [NCBI, ExPASy, EBI, Israel, Japan]
Akrigg A., Wilkinson G.W.G., Oram J.D.;
"The structure of the major immediate early gene of human cytomegalovirus strain AD169.";
Virus Res. 2:107-121(1985).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
PubMed=2161319 [NCBI, ExPASy, EBI, Israel, Japan]
Chee M.S., Bankier A.T., Beck S., Bohni R., Brown C.M., Cerny R., Horsnell T., Hutchison C.A. III, Kouzarides T., Martignetti J.A., Preddie E., Satchwell S.C., Tomlinson P., Weston K.M., Barrell B.G.;
"Analysis of the protein-coding content of the sequence of human cytomegalovirus strain AD169.";
Curr. Top. Microbiol. Immunol. 154:125-169(1990).
[3]
GENOME REANNOTATION.
DOI=10.1099/vir.0.18606-0; PubMed=12533697 [NCBI, ExPASy, EBI, Israel, Japan]
Davison A.J., Dolan A., Akter P., Addison C., Dargan D.J., Alcendor D.J., McGeoch D.J., Hayward G.S.;
"The human cytomegalovirus genome revisited: comparison with the chimpanzee cytomegalovirus genome.";
J. Gen. Virol. 84:17-28(2003).
[4]
ERRATUM.
Davison A.J., Dolan A., Akter P., Addison C., Dargan D.J., Alcendor D.J., McGeoch D.J., Hayward G.S.;
J. Gen. Virol. 84:1053-1053(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
X17403; CAA35325.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
M21295; AAA45980.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
BK000394; DAA00112.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR S09890; EDBEM5.
RefSeq YP_002608299.1; -.
3D structure databases
ModBase P13202.
Ontologies
GO
GO:0042025; Cellular component: host cell nucleus (inferred from electronic annotation from UniProtKB-SubCell).
GO:0005634; Cellular component: nucleus (inferred from electronic annotation from UniProtKB-KW).
GO:0050792; Biological process: regulation of viral reproduction (inferred from electronic annotation from InterPro).
QuickGo view.
Family and domain databases
InterPro IPR010855; Cytomega_IE1.
Graphical view of domain structure.
Pfam PF07340; Herpes_IE1; 1.
Pfam graphical view of domain structure.
Genome annotation databases
GeneID 1487822; -.
Other
ProtoNet P13202.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Early protein; Nucleus.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   491  491     55 kDa immediate-early protein 1. PRO_0000115355
Sequence information
Length: 491 AA [This is the length of the unprocessed precursor] Molecular weight: 55110 Da [This is the MW of the unprocessed precursor] CRC64: CC5966B00CD8C8B4 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MESSAKRKMD PDNPDEGPSS KVPRPETPVT KATTFLQTML RKEVNSQLSL GDPLFPELAE 

        70         80         90        100        110        120 
ESLKTFEQVT EDCNENPEKD VLAELVKQIK VRVDMVRHRI KEHMLKKYTQ TEEKFTGAFN 

       130        140        150        160        170        180 
MMGGCLQNAL DILDKVHEPF EEMKCIGLTM QSMYENYIVP EDKREMWMAC IKELHDVSKG 

       190        200        210        220        230        240 
AANKLGGALQ AKARAKKDEL RRKMMYMCYR NIEFFTKNSA FPKTTNGCSQ AMAALQNLPQ 

       250        260        270        280        290        300 
CSPDEIMAYA QKIFKILDEE RDKVLTHIDH IFMDILTTCV ETMCNEYKVT SDACMMTMYG 

       310        320        330        340        350        360 
GISLLSEFCR VLCCYVLEET SVMLAKRPLI TKPEVISVMK RRIEEICMKV FAQYILGADP 

       370        380        390        400        410        420 
LRVCSPSVDD LRAIAEESDE EEAIVAYTLA TAGVSSSDSL VSPPESPVPA TIPLSSVIVA 

       430        440        450        460        470        480 
ENSDQEESEQ SDEEEEEGAQ EEREDTVSVK SEPVSEIEEV APEEEEDGAE EPTASGGKST 

       490 
HPMVTRSKAD Q 

P13202 in FASTA format

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