[1]
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NUCLEOTIDE SEQUENCE [MRNA].
TISSUE=Bone marrow;
DOI=10.1210/me.7.2.199; PubMed=8469233 [NCBI, ExPASy, EBI, Israel, Japan]
Palfree R.G.E.,
Sadro L.C.,
Solomon S.;
"The gene encoding the human corticostatin HP-4 precursor contains a recent 86-base duplication and is located on chromosome 8.";
Mol. Endocrinol. 7:199-205(1993).
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[2]
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PROTEIN SEQUENCE OF 64-96.
DOI=10.1016/S0006-291X(88)81118-5; PubMed=2843187 [NCBI, ExPASy, EBI, Israel, Japan]
Singh A.,
Bateman A.,
Zhu Q.,
Shimasaki S.,
Esch F.,
Solomon S.;
"Structure of a novel human granulocyte peptide with anti-ACTH activity.";
Biochem. Biophys. Res. Commun. 155:524-529(1988).
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[3]
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PROTEIN SEQUENCE OF 64-96.
PubMed=2500436 [NCBI, ExPASy, EBI, Israel, Japan]
Wilde C.G.,
Griffith J.E.,
Marra M.N.,
Snable J.L.,
Scott R.W.;
"Purification and characterization of human neutrophil peptide 4, a novel member of the defensin family.";
J. Biol. Chem. 264:11200-11203(1989).
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[4]
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PROTEIN SEQUENCE OF 64-83.
DOI=10.1073/pnas.86.14.5610; PubMed=2501794 [NCBI, ExPASy, EBI, Israel, Japan]
Gabay J.E.,
Scott R.W.,
Campanelli D.,
Griffith J.,
Wilde C.,
Marra M.N.,
Seeger M.,
Nathan C.F.;
"Antibiotic proteins of human polymorphonuclear leukocytes.";
Proc. Natl. Acad. Sci. U.S.A. 86:5610-5614(1989).
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[5]
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FUNCTION.
DOI=10.1128/AAC.49.1.269-275.2005; PubMed=15616305 [NCBI, ExPASy, EBI, Israel, Japan]
Ericksen B.,
Wu Z.,
Lu W.,
Lehrer R.I.;
"Antibacterial activity and specificity of the six human alpha-defensins.";
Antimicrob. Agents Chemother. 49:269-275(2005).
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[6]
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FUNCTION.
DOI=10.1016/j.febslet.2004.11.062; PubMed=15620707 [NCBI, ExPASy, EBI, Israel, Japan]
Wu Z.,
Cocchi F.,
Gentles D.,
Ericksen B.,
Lubkowski J.,
Devico A.,
Lehrer R.I.,
Lu W.;
"Human neutrophil alpha-defensin 4 inhibits HIV-1 infection in vitro.";
FEBS Lett. 579:162-166(2005).
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[7]
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X-RAY CRYSTALLOGRAPHY (1.6 ANGSTROMS) OF 64-96, SUBUNIT, AND DISULFIDE BONDS.
DOI=10.1110/ps.062336606; PubMed=17088326 [NCBI, ExPASy, EBI, Israel, Japan]
Szyk A.,
Wu Z.,
Tucker K.,
Yang D.,
Lu W.,
Lubkowski J.;
"Crystal structures of human alpha-defensins HNP4, HD5, and HD6.";
Protein Sci. 15:2749-2760(2006).
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[8]
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VARIANT [LARGE SCALE ANALYSIS] GLN-74.
DOI=10.1126/science.1133427; PubMed=16959974 [NCBI, ExPASy, EBI, Israel, Japan]
Sjoeblom T.,
Jones S.,
Wood L.D.,
Parsons D.W.,
Lin J.,
Barber T.D.,
Mandelker D.,
Leary R.J.,
Ptak J.,
Silliman N.,
Szabo S.,
Buckhaults P.,
Farrell C.,
Meeh P.,
Markowitz S.D.,
Willis J.,
Dawson D.,
Willson J.K.V.,
Gazdar A.F., ![]()
Hartigan J.,
Wu L.,
Liu C.,
Parmigiani G.,
Park B.H.,
Bachman K.E.,
Papadopoulos N.,
Vogelstein B.,
Kinzler K.W.,
Velculescu V.E.;
"The consensus coding sequences of human breast and colorectal cancers.";
Science 314:268-274(2006).
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