[1]	NUCLEOTIDE SEQUENCE [GENOMIC DNA]. PubMed=2839594 [NCBI, ExPASy, EBI, Israel, Japan] McGeoch D.J., Dalrymple M.A., Davison A.J., Dolan A., Frame M.C., McNab D., Perry L.J., Scott J.E., Taylor P.; "The complete DNA sequence of the long unique region in the genome of herpes simplex virus type 1."; J. Gen. Virol. 69:1531-1574(1988).
[2]	IDENTIFICATION OF PROTEIN, AND SUBCELLULAR LOCATION. PubMed=2177087 [NCBI, ExPASy, EBI, Israel, Japan] McLean G., Rixon F., Langeland N., Haarr L., Marsden H.; "Identification and characterization of the virion protein products of herpes simplex virus type 1 gene UL47."; J. Gen. Virol. 71:2953-2960(1990).
[3]	SUBCELLULAR LOCATION, AND NUCLEAR LOCALIZATION SIGNAL. DOI=10.1128/JVI.75.6.2566-2574.2001; PubMed=11222679 [NCBI, ExPASy, EBI, Israel, Japan] Donnelly M., Elliott G.; "Nuclear localization and shuttling of herpes simplex virus tegument protein VP13/14."; J. Virol. 75:2566-2574(2001).
[4]	SUBCELLULAR LOCATION, AND NUCLEAR EXPORT SIGNAL. DOI=10.1128/JVI.01403-08; PubMed=18715912 [NCBI, ExPASy, EBI, Israel, Japan] Williams P., Verhagen J., Elliott G.; "Characterization of a CRM1-dependent nuclear export signal in the C terminus of herpes simplex virus type 1 tegument protein UL47."; J. Virol. 82:10946-10952(2008).

Comments

SUBCELLULAR LOCATION: Virion tegument. Host nucleus. Host cytoplasm. Note=Major tegument protein of the virion. Undergoes nucleocytoplasmic shuttling during infection.
DOMAIN: The nuclear export signal is CRM1-dependent.
MISCELLANEOUS: Expressed in late in the infection.
SIMILARITY: Belongs to the alphaherpesvirinae HHV-1 UL47 family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

X14112; CAA32297.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

PIR

B30089; TNBEF7.

RefSeq

NP_044649.1; -.

3D structure databases

ModBase

P10231.

Ontologies

GO:0005737;	Cellular component: cytoplasm (inferred from electronic annotation from UniProtKB-KW).
GO:0030430;	Cellular component: host cell cytoplasm (inferred from electronic annotation from UniProtKB-SubCell).
GO:0042025;	Cellular component: host cell nucleus (inferred from electronic annotation from UniProtKB-SubCell).
GO:0005634;	Cellular component: nucleus (inferred from electronic annotation from UniProtKB-KW).
GO:0019033;	Cellular component: viral tegument (inferred from electronic annotation from UniProtKB-SubCell).
GO:0006355;	Biological process: regulation of transcription, DNA-dependent (inferred from electronic annotation from UniProtKB-KW).
GO:0006350;	Biological process: transcription (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.

Family and domain databases

InterPro

IPR005029; Herpes_UL47.
Graphical view of domain structure.

Pfam

PF03362; Herpes_UL47; 1.
Pfam graphical view of domain structure.

Genome annotation databases

GeneID

2703415; -.

Other

ProtoNet

P10231.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; Cytoplasm; Late protein; Nucleus; Transcription; Transcription regulation; Virion; Virion tegument.

Features

Feature table viewer

Feature aligner

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 693`	`693`	`Tegument protein UL47.`	`PRO_0000116073`
`MOTIF`	`63 75`	`13`	`Nuclear localization signal.`
`MOTIF`	`647 670`	`24`	`Nuclear export signal.`

Sequence information

Length: 693 AA [This is the length of the unprocessed precursor]

Molecular weight: 73817 Da [This is the MW of the unprocessed precursor]

CRC64: 283737D7D33B5C93 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MSAREPAGRR RRASTRPRAS PVADEPAGDG VGFMGYLRAV FRGDDDSELE ALEEMAGDEP 

        70         80         90        100        110        120 
PVRRRREGPR ARRRRASEAP PTSHRRASRQ RPGPDAARSQ SVRGRLDDDD EVPRGPPQAR 

       130        140        150        160        170        180 
QGGYLGPVDA RAILGRVGGS RVAPSPLFLE ELQYEEDDYP EAVGPEDGGG ARSPPKVEVL 

       190        200        210        220        230        240 
EGRVPGPELR AAFPLDRLAP QVAVWDESVR SALALGHPAG FYPCPDSAFG LSRVGVMHFA 

       250        260        270        280        290        300 
SPDNPAVFFR QTLQQGEALA WYITGDGILD LTDRRTKTSP AQAMSFLADA VVRLAINGWV 

       310        320        330        340        350        360 
CGTRLHAEAR GSDLDDRAAE LRRQFASLTA LRPVGAAAVP LLSAGGLVSP QSGPDAAVFR 

       370        380        390        400        410        420 
SSLGSLLYWP GVRALLDRDC RVAARYAGRM TYLATGALLA RFNPDAVRCV LTREAAFLGR 

       430        440        450        460        470        480 
VLDVLAVMAE QTVQWLSVVV GARLHPHVHH PAFADVAREE LFRALPLGSP AVVGAEHEAL 

       490        500        510        520        530        540 
GDTAARRLLA NSGLNAVLGA AVYALHTALA TVTLKYARAC GDAHRRRDDA AATRAILAAG 

       550        560        570        580        590        600 
LVLQRLLGFA DTVVACVTLA AFDGGFTAPE VGTYTPLRYA CVLRATQPLY ARTTPAKFWA 

       610        620        630        640        650        660 
DVRAAAEHVD LRPASSAPRA PVSGTADPAF LLKDLEPFPP APVSGGSVLG PRVRVVDIMS 

       670        680        690 
QFRKLLMGDE GAAALRAHVS GRRATGLGGP PRP

P10231 in FASTA format

View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools