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UniProtKB/Swiss-Prot entry P0A7B3


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name PPNK_ECOLI
Primary accession number P0A7B3
Secondary accession numbers P37768 P46140 P77490
Integrated into Swiss-Prot on June 7, 2005
Sequence was last modified on June 7, 2005 (Sequence version 1)
Annotations were last modified on    June 16, 2009 (Entry version 40)
Name and origin of the protein
Protein name Probable inorganic polyphosphate/ATP-NAD kinase
Synonyms Poly(P)/ATP NAD kinase
EC 2.7.1.23
Gene name
Name: ppnK
Synonyms: yfjB, yfjE
OrderedLocusNames: b2615, JW2596
From
Escherichia coli (strain K12) [TaxID: 83333] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Escherichia.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
DOI=10.1093/dnares/4.2.91; PubMed=9205837 [NCBI, ExPASy, EBI, Israel, Japan]
Yamamoto Y., Aiba H., Baba T., Hayashi K., Inada T., Isono K., Itoh T., Kimura S., Kitagawa M., Makino K., Miki T., Mitsuhashi N., Mizobuchi K., Mori H., Nakade S., Nakamura Y., Nashimoto H., Oshima T., Oyama S., Saito N., Sampei G., Satoh Y., Sivasundaram S., Tagami H., Takahashi H., Takeda J., Takemoto K., Uehara K., Wada C., Yamagata S., Horiuchi T.;
"Construction of a contiguous 874-kb sequence of the Escherichia coli-K12 genome corresponding to 50.0-68.8 min on the linkage map and analysis of its sequence features.";
DNA Res. 4:91-113(1997).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=K12 / MG1655 / ATCC 47076;
DOI=10.1126/science.277.5331.1453; PubMed=9278503 [NCBI, ExPASy, EBI, Israel, Japan]
Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y.;
"The complete genome sequence of Escherichia coli K-12.";
Science 277:1453-1474(1997).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
DOI=10.1038/msb4100049; PubMed=16738553 [NCBI, ExPASy, EBI, Israel, Japan]
Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.";
Mol. Syst. Biol. 2:E1-E5(2006).
[4]
NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-163.
STRAIN=B178;
DOI=10.1093/nar/16.15.7545; PubMed=3045760 [NCBI, ExPASy, EBI, Israel, Japan]
Lipinska B., King J., Ang D., Georgopoulos C.;
"Sequence analysis and transcriptional regulation of the Escherichia coli grpE gene, encoding a heat shock protein.";
Nucleic Acids Res. 16:7545-7562(1988).
[5]
NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 194-292.
STRAIN=K12;
DOI=10.1093/nar/15.13.5041; PubMed=3037486 [NCBI, ExPASy, EBI, Israel, Japan]
Rostas K., Morton S.J., Picksley S.M., Lloyd R.G.;
"Nucleotide sequence and LexA regulation of the Escherichia coli recN gene.";
Nucleic Acids Res. 15:5041-5049(1987).
[6]
IDENTIFICATION.
DOI=10.1093/nar/22.22.4756; PubMed=7984428 [NCBI, ExPASy, EBI, Israel, Japan]
Borodovsky M., Rudd K.E., Koonin E.V.;
"Intrinsic and extrinsic approaches for detecting genes in a bacterial genome.";
Nucleic Acids Res. 22:4756-4767(1994).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
U36840; AAA79785.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
U00096; AAC75664.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AP009048; BAA16500.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
X07863; -; NOT_ANNOTATED_CDS; Genomic_DNA.[EMBL / GenBank / DDBJ]
Y00357; -; NOT_ANNOTATED_CDS; Genomic_DNA.[EMBL / GenBank / DDBJ]
PIR B65040; B65040.
RefSeq AP_003195.1; -.
NP_417105.1; -.
3D structure databases
SMR P0A7B3; 4-292.
ModBase P0A7B3.
Enzyme and pathway databases
BioCyc EcoCyc:MON0-541; -.
MetaCyc:MON0-541; -.
Organism-specific databases
EchoBASE EB2109; -.
EcoGene EG12192; ppnK.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from UniProtKB-SubCell).
GO:0005524; Molecular function: ATP binding (inferred from electronic annotation from UniProtKB-KW).
GO:0046872; Molecular function: metal ion binding (inferred from electronic annotation from HAMAP).
GO:0003951; Molecular function: NAD+ kinase activity (inferred from electronic annotation from HAMAP).
GO:0008152; Biological process: metabolic process (inferred from electronic annotation from InterPro).
QuickGo view.
Family and domain databases
HAMAP MF_00361; -; 1.
PBIL [Tree]
InterPro IPR017437; ATP-NAD_kinase_PpnK-typ_all-b.
IPR002504; ATP_NADK.
Graphical view of domain structure.
Gene3D G3DSA:2.60.200.30; ATP-NAD_kinase_PpnK-typ; 1.
PANTHER PTHR20275; ATP_NADK; 1.
Pfam PF01513; NAD_kinase; 1.
Pfam graphical view of domain structure.
Genome annotation databases
GeneID 947092; -.
GenomeReviews AP009048_GR; JW2596.
U00096_GR; b2615.
KEGG ecj:JW2596; -.
eco:b2615; -.
Phylogenomic databases
HOGENOM P0A7B3; -.
OMA P0A7B3; MEQFRNI.
Genome annotation databases
CMR P0A7B3; b2615.
Other
ProtoNet P0A7B3.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
ATP-binding; Complete proteome; Cytoplasm; Kinase; NAD; NADP; Nucleotide-binding; Transferase.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   292  292     Probable inorganic polyphosphate/ATP-NAD kinase. PRO_0000120616
Sequence information
Length: 292 AA [This is the length of the unprocessed precursor] Molecular weight: 32566 Da [This is the MW of the unprocessed precursor] CRC64: D1E631658408F2E1 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MNNHFKCIGI VGHPRHPTAL TTHEMLYRWL CTKGYEVIVE QQIAHELQLK NVKTGTLAEI 

        70         80         90        100        110        120 
GQLADLAVVV GGDGNMLGAA RTLARYDIKV IGINRGNLGF LTDLDPDNAQ QQLADVLEGH 

       130        140        150        160        170        180 
YISEKRFLLE AQVCQQDCQK RISTAINEVV LHPGKVAHMI EFEVYIDEIF AFSQRSDGLI 

       190        200        210        220        230        240 
ISTPTGSTAY SLSAGGPILT PSLDAITLVP MFPHTLSARP LVINSSSTIR LRFSHRRNDL 

       250        260        270        280        290 
EISCDSQIAL PIQEGEDVLI RRCDYHLNLI HPKDYSYFNT LSTKLGWSKK LF 

P0A7B3 in FASTA format

View entry in raw text format (no links)
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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