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UniProtKB/Swiss-Prot entry P09785


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name PHNA_PSEAE
Primary accession number P09785
Secondary accession numbers None
Integrated into Swiss-Prot on July 1, 1989
Sequence was last modified on February 1, 1991 (Sequence version 2)
Annotations were last modified on    November 25, 2008 (Entry version 68)
Name and origin of the protein
Protein name Anthranilate synthase component 1
Synonyms EC 4.1.3.27
Anthranilate synthase component I
Gene name
Name: phnA
OrderedLocusNames: PA1001
From
Pseudomonas aeruginosa [TaxID: 287] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas.
Protein existence 4: Predicted;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228, and PAC174;
PubMed=2153661 [NCBI, ExPASy, EBI, Israel, Japan]
Essar D.W., Eberly L., Hadero A., Crawford I.P.;
"Identification and characterization of genes for a second anthranilate synthase in Pseudomonas aeruginosa: interchangeability of the two anthranilate synthases and evolutionary implications.";
J. Bacteriol. 172:884-900(1990).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228;
DOI=10.1038/35023079; PubMed=10984043 [NCBI, ExPASy, EBI, Israel, Japan]
Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P., Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M., Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y., Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M., Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J., Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
"Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen.";
Nature 406:959-964(2000).
[3]
NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 383-530.
PubMed=3127654 [NCBI, ExPASy, EBI, Israel, Japan]
Crawford I.P., Eberly L.;
"Structure and regulation of the anthranilate synthase genes in Pseudomonas aeruginosa: I. Sequence of trpG encoding the glutamine amidotransferase subunit.";
Mol. Biol. Evol. 3:436-448(1986).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
M33810; AAA88448.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
M33811; AAA88451.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AE004091; AAG04390.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
M15733; -; NOT_ANNOTATED_CDS; Genomic_DNA.[EMBL / GenBank / DDBJ]
PIR B83519; B83519.
E35116; E35116.
RefSeq NP_249692.1; -.
3D structure databases
HSSP P00897; 1I7S. [HSSP ENTRY / PDB]
ModBase P09785.
Enzyme and pathway databases
BioCyc PAER208964:PA1001-MON; -.
Organism-specific databases
PseudoCAP PA1001; -.
Ontologies
GO
GO:0004049; Molecular function: anthranilate synthase activity (inferred from electronic annotation from InterPro).
GO:0009058; Biological process: biosynthetic process (inferred from electronic annotation from InterPro).
QuickGo view.
Family and domain databases
InterPro IPR006805; Anth_synth_I_N.
IPR015890; Chorismate-bd_C.
IPR005801; TRPE_1_chor_bd.
IPR005257; TrpE_synth.
Graphical view of domain structure.
Gene3D G3DSA:3.60.120.10; TRPE_1_chor_bd; 1.
PANTHER PTHR11236; TRPE_1_chor_bd; 1.
Pfam PF04715; Anth_synt_I_N; 1.
PF00425; Chorismate_bind; 1.
Pfam graphical view of domain structure.
PRINTS PR00095; ANTSNTHASEI.
ProDom PD000779; Anth_synth_chor; 1.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR00565; trpE_proteo; 1.
Genome annotation databases
GeneID 878421; -.
GenomeReviews AE004091_GR; PA1001.
KEGG pae:PA1001; -.
NMPDR fig|208964.1.peg.1002; -.
Phylogenomic databases
HOGENOM P09785; -.
Genome annotation databases
CMR P09785; PA1001.
Other
ProtoNet P09785.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Lyase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   530  530     Anthranilate synthase component 1. PRO_0000058388
VARIANT   4     4  1     R -> G (in strain: PAC174). 
VARIANT   91    91  1     D -> A (in strain: PAC174). 
VARIANT   111   111  1     Q -> P (in strain: PAC174). 
VARIANT   114   114  1     S -> P (in strain: PAC174). 
VARIANT   145   145  1     V -> A (in strain: PAC174). 
VARIANT   337   337  1     R -> C (in strain: PAC174). 
Sequence information
Length: 530 AA [This is the length of the unprocessed precursor] Molecular weight: 58670 Da [This is the MW of the unprocessed precursor] CRC64: 0E6280AC3A23A066 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MGARRWLVSG VGYRLEESLE YRTLVPEALS IWRMAGANRM LFDCFDVDSK AARRSVAILS 

        70         80         90        100        110        120 
SCLRIECWGR DVVLRALNSN GRALLAPLSE DCPAQVTCLR DGDTLHWRFP QEESHADEWR 

       130        140        150        160        170        180 
RLHGLSSLEA LRRVLGTLGD AEGPVLLGGL FSFDLAEQFE PLPAPAEPAR HCPDYLFLVP 

       190        200        210        220        230        240 
ELLLDIDHLA RRTSLQAFVH DPAGHDRLAA SLRQCADEFH GAVEEASESP VAGVRAGNYQ 

       250        260        270        280        290        300 
VDLDDASFAR QVERLQAHVR AGDVFQIVPS RSFSMPCADP WRAYRQLCLR NPSPYRFFLD 

       310        320        330        340        350        360 
AGDFCLFGAS PESALKYDAE SREVELYPIA GTRPRGRDAR GAIDAELDNR LEAELRLDAK 

       370        380        390        400        410        420 
EIAEHMMLVD LARNDLARVC RSGTRQVRDM LKVDRYSHVM HLVSRVAGEL HGELDALHAY 

       430        440        450        460        470        480 
RACLNMGTLV GAPKVRAMQL LRQYEDGYRG SYGGAIGILD SAGNLDTSIV IRSAEVREGI 

       490        500        510        520        530 
ARVRAGAGVV LDSDPRLEAE ETRNKALAVL TAVAAAERER GERDAHHAVG 

P09785 in FASTA format

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