[1]
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NUCLEOTIDE SEQUENCE [MRNA].
DOI=10.1073/pnas.85.10.3435; PubMed=2835772 [NCBI, ExPASy, EBI, Israel, Japan]
Gronwald R.G.K.,
Grant F.J.,
Haldeman B.A.,
Hart C.E.,
O'Hara P.J.,
Hagen F.S.,
Ross R.,
Bowen-Pope D.F.,
Murray M.J.;
"Cloning and expression of a cDNA coding for the human platelet-derived growth factor receptor: evidence for more than one receptor class.";
Proc. Natl. Acad. Sci. U.S.A. 85:3435-3439(1988).
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[2]
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NUCLEOTIDE SEQUENCE [MRNA].
PubMed=2850496 [NCBI, ExPASy, EBI, Israel, Japan]
Claesson-Welsh L.,
Eriksson A.,
Moren A.,
Severinsson L.,
Ek B.,
Oestman A.,
Betsholtz C.,
Heldin C.-H.;
"cDNA cloning and expression of a human platelet-derived growth factor (PDGF) receptor specific for B-chain-containing PDGF molecules.";
Mol. Cell. Biol. 8:3476-3486(1988).
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[3]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], AND VARIANT PHE-180.
TISSUE=Brain;
DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan]
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
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[4]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 548-569.
DOI=10.1038/sj.onc.1201267; PubMed=9285559 [NCBI, ExPASy, EBI, Israel, Japan]
Chi K.D.,
McPhee R.A.,
Wagner A.S.,
Dietz J.J.,
Pantazis P.,
Goustin A.S.;
"Integration of proviral DNA into the PDGF beta-receptor gene in HTLV-I-infected T-cells results in a novel tyrosine kinase product with transforming activity.";
Oncogene 15:1051-1057(1997).
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[5]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1046-1106.
DOI=10.1016/0092-8674(88)90224-3; PubMed=2846185 [NCBI, ExPASy, EBI, Israel, Japan]
Roberts W.M.,
Look A.T.,
Roussel M.F.,
Sherr C.J.;
"Tandem linkage of human CSF-1 receptor (c-fms) and PDGF receptor genes.";
Cell 55:655-661(1988).
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[6]
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PROTEIN SEQUENCE OF 33-47.
DOI=10.1110/ps.04682504; PubMed=15340161 [NCBI, ExPASy, EBI, Israel, Japan]
Zhang Z.,
Henzel W.J.;
"Signal peptide prediction based on analysis of experimentally verified cleavage sites.";
Protein Sci. 13:2819-2824(2004).
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[7]
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PHOSPHORYLATION AT TYR-751 AND TYR-857.
DOI=10.1016/0092-8674(89)90510-2; PubMed=2550144 [NCBI, ExPASy, EBI, Israel, Japan]
Kazlauskas A.,
Cooper J.A.;
"Autophosphorylation of the PDGF receptor in the kinase insert region regulates interactions with cell proteins.";
Cell 58:1121-1133(1989).
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[8]
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INTERACTION WITH SHB.
PubMed=8302579 [NCBI, ExPASy, EBI, Israel, Japan]
Welsh M.,
Mares J.,
Karlsson T.,
Lavergne C.,
Breant B.,
Claesson-Welsh L.;
"Shb is a ubiquitously expressed Src homology 2 protein.";
Oncogene 9:19-27(1994).
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[9]
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CHROMOSOMAL TRANSLOCATION WITH TRIP11.
PubMed=9373237 [NCBI, ExPASy, EBI, Israel, Japan]
Abe A.,
Emi N.,
Tanimoto M.,
Terasaki H.,
Marunouchi T.,
Saito H.;
"Fusion of the platelet-derived growth factor receptor beta to a novel gene CEV14 in acute myelogenous leukemia after clonal evolution.";
Blood 90:4271-4277(1997).
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[10]
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INTERACTION WITH APS.
DOI=10.1038/sj.onc.1202326; PubMed=9989826 [NCBI, ExPASy, EBI, Israel, Japan]
Yokouchi M.,
Wakioka T.,
Sakamoto H.,
Yasukawa H.,
Ohtsuka S.,
Sasaki A.,
Ohtsubo M.,
Valius M.,
Inoue A.,
Komiya S.,
Yoshimura A.;
"APS, an adaptor protein containing PH and SH2 domains, is associated with the PDGF receptor and c-Cbl and inhibits PDGF-induced mitogenesis.";
Oncogene 18:759-767(1999).
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[11]
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INTERACTION WITH PIK3C2B.
DOI=10.1128/MCB.20.11.3817-3830.2000; PubMed=10805725 [NCBI, ExPASy, EBI, Israel, Japan]
Arcaro A.,
Zvelebil M.J.,
Wallasch C.,
Ullrich A.,
Waterfield M.D.,
Domin J.;
"Class II phosphoinositide 3-kinases are downstream targets of activated polypeptide growth factor receptors.";
Mol. Cell. Biol. 20:3817-3830(2000).
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[12]
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FUNCTION AS A RECEPTOR FOR PDGFD.
DOI=10.1038/35074588; PubMed=11331881 [NCBI, ExPASy, EBI, Israel, Japan]
Bergsten E.,
Uutela M.,
Li X.,
Pietras K.,
Oestman A.,
Heldin C.-H.,
Alitalo K.,
Eriksson U.;
"PDGF-D is a specific, protease-activated ligand for the PDGF beta-receptor.";
Nat. Cell Biol. 3:512-516(2001).
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[13]
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CHROMOSOMAL TRANSLOCATION WITH ETV6.
DOI=10.1056/NEJMoa020150; PubMed=12181402 [NCBI, ExPASy, EBI, Israel, Japan]
Apperley J.F.,
Gardembas M.,
Melo J.V.,
Russell-Jones R.,
Bain B.J.,
Baxter E.J.,
Chase A.,
Chessells J.M.,
Colombat M.,
Dearden C.E.,
Dimitrijevic S.,
Mahon F.-X.,
Marin D.,
Nikolova Z.,
Olavarria E.,
Silberman S.,
Schultheis B.,
Cross N.C.P.,
Goldman J.M.;
"Response to imatinib mesylate in patients with chronic myeloproliferative diseases with rearrangements of the platelet-derived growth factor receptor beta.";
N. Engl. J. Med. 347:481-487(2002).
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[14]
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CHROMOSOMAL TRANSLOCATION WITH PDE4DIP.
DOI=10.1182/blood-2003-04-1150; PubMed=12907457 [NCBI, ExPASy, EBI, Israel, Japan]
Wilkinson K.,
Velloso E.R.P.,
Lopes L.F.,
Lee C.,
Aster J.C.,
Shipp M.A.,
Aguiar R.C.T.;
"Cloning of the t(1;5)(q23;q33) in a myeloproliferative disorder associated with eosinophilia: involvement of PDGFRB and response to imatinib.";
Blood 102:4187-4190(2003).
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[15]
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CHROMOSOMAL TRANSLOCATION WITH SPECC1.
DOI=10.1158/0008-5472.CAN-03-4026; PubMed=15087372 [NCBI, ExPASy, EBI, Israel, Japan]
Morerio C.,
Acquila M.,
Rosanda C.,
Rapella A.,
Dufour C.,
Locatelli F.,
Maserati E.,
Pasquali F.,
Panarello C.;
"HCMOGT-1 is a novel fusion partner to PDGFRB in juvenile myelomonocytic leukemia with t(5;17)(q33;p11.2).";
Cancer Res. 64:2649-2651(2004).
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[16]
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X-RAY CRYSTALLOGRAPHY (1.79 ANGSTROMS) OF 751-755 IN COMPLEX WITH PIK3R1, AND COMPARISON WITH NMR ANALYSIS.
DOI=10.1107/S0907444901012434; PubMed=11567151 [NCBI, ExPASy, EBI, Israel, Japan]
Pauptit R.A.,
Dennis C.A.,
Derbyshire D.J.,
Breeze A.L.,
Weston S.A.,
Rowsell S.,
Murshudov G.N.;
"NMR trial models: experiences with the colicin immunity protein Im7 and the p85alpha C-terminal SH2-peptide complex.";
Acta Crystallogr. D 57:1397-1404(2001).
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[17]
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X-RAY CRYSTALLOGRAPHY (2.2 ANGSTROMS) OF 1102-1106 IN COMPLEX WITH SLC9A3R1 AND PDGFRA.
DOI=10.1074/jbc.M201507200; PubMed=11882663 [NCBI, ExPASy, EBI, Israel, Japan]
Karthikeyan S.,
Leung T.,
Ladias J.A.A.;
"Structural determinants of the Na+/H+ exchanger regulatory factor interaction with the beta 2 adrenergic and platelet-derived growth factor receptors.";
J. Biol. Chem. 277:18973-18978(2002).
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[18]
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VARIANTS [LARGE SCALE ANALYSIS] PHE-29; LYS-282; LYS-485; HIS-589; TYR-718 AND ILE-882.
DOI=10.1038/nature05610; PubMed=17344846 [NCBI, ExPASy, EBI, Israel, Japan]
Greenman C.,
Stephens P.,
Smith R.,
Dalgliesh G.L.,
Hunter C.,
Bignell G.,
Davies H.,
Teague J.,
Butler A.,
Stevens C.,
Edkins S.,
O'Meara S.,
Vastrik I.,
Schmidt E.E.,
Avis T.,
Barthorpe S.,
Bhamra G.,
Buck G.,
Choudhury B., ![]()
Clements J.,
Cole J.,
Dicks E.,
Forbes S.,
Gray K.,
Halliday K.,
Harrison R.,
Hills K.,
Hinton J.,
Jenkinson A.,
Jones D.,
Menzies A.,
Mironenko T.,
Perry J.,
Raine K.,
Richardson D.,
Shepherd R.,
Small A.,
Tofts C.,
Varian J.,
Webb T.,
West S.,
Widaa S.,
Yates A.,
Cahill D.P.,
Louis D.N.,
Goldstraw P.,
Nicholson A.G.,
Brasseur F.,
Looijenga L.,
Weber B.L.,
Chiew Y.-E.,
DeFazio A.,
Greaves M.F.,
Green A.R.,
Campbell P.,
Birney E.,
Easton D.F.,
Chenevix-Trench G.,
Tan M.-H.,
Khoo S.K.,
Teh B.T.,
Yuen S.T.,
Leung S.Y.,
Wooster R.,
Futreal P.A.,
Stratton M.R.;
"Patterns of somatic mutation in human cancer genomes.";
Nature 446:153-158(2007).
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