[1]
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NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), AND ALTERNATIVE SPLICING.
TISSUE=Lymphocyte;
DOI=10.1084/jem.166.5.1548; PubMed=2824653 [NCBI, ExPASy, EBI, Israel, Japan]
Streuli M.,
Hall L.R.,
Saga Y.,
Schlossman S.F.,
Saito H.;
"Differential usage of three exons generates at least five different mRNAs encoding human leukocyte common antigens.";
J. Exp. Med. 166:1548-1566(1987).
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[2]
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NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2), AND ALTERNATIVE SPLICING.
PubMed=2956090 [NCBI, ExPASy, EBI, Israel, Japan]
Ralph S.J.,
Thomas M.L.,
Morton C.C.,
Trowbridge I.S.;
"Structural variants of human T200 glycoprotein (leukocyte-common antigen).";
EMBO J. 6:1251-1257(1987).
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[3]
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NUCLEOTIDE SEQUENCE OF 146-192.
PubMed=2531281 [NCBI, ExPASy, EBI, Israel, Japan]
Tsai A.Y.M.,
Streuli M.,
Saito H.;
"Integrity of the exon 6 sequence is essential for tissue-specific alternative splicing of human leukocyte common antigen pre-mRNA.";
Mol. Cell. Biol. 9:4550-4555(1989).
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[4]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 191-1304.
TISSUE=Placenta;
PubMed=2971730 [NCBI, ExPASy, EBI, Israel, Japan]
Hall L.R.,
Streuli M.,
Schlossman S.F.,
Saito H.;
"Complete exon-intron organization of the human leukocyte common antigen (CD45) gene.";
J. Immunol. 141:2781-2787(1988).
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[5]
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FUNCTION.
PubMed=2845400 [NCBI, ExPASy, EBI, Israel, Japan]
Charbonneau H.,
Tonks N.K.,
Walsh K.A.,
Fischer E.H.;
"The leukocyte common antigen (CD45): a putative receptor-linked protein tyrosine phosphatase.";
Proc. Natl. Acad. Sci. U.S.A. 85:7182-7186(1988).
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[6]
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MUTAGENESIS.
PubMed=1695146 [NCBI, ExPASy, EBI, Israel, Japan]
Streuli M.,
Krueger N.X.,
Thai T.,
Tang M.,
Saito H.;
"Distinct functional roles of the two intracellular phosphatase like domains of the receptor-linked protein tyrosine phosphatases LCA and LAR.";
EMBO J. 9:2399-2407(1990).
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[7]
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INTERACTION WITH SKAP1, MUTAGENESIS OF CYS-851, AND FUNCTION.
DOI=10.1128/MCB.22.8.2673-2686.2002; PubMed=11909961 [NCBI, ExPASy, EBI, Israel, Japan]
Wu L.,
Fu J.,
Shen S.-H.;
"SKAP55 coupled with CD45 positively regulates T-cell receptor-mediated gene transcription.";
Mol. Cell. Biol. 22:2673-2686(2002).
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[8]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-995; SER-1003 AND SER-1007, AND MASS SPECTROMETRY.
TISSUE=Epithelium;
DOI=10.1073/pnas.0404720101; PubMed=15302935 [NCBI, ExPASy, EBI, Israel, Japan]
Beausoleil S.A.,
Jedrychowski M.,
Schwartz D.,
Elias J.E.,
Villen J.,
Li J.,
Cohn M.A.,
Cantley L.C.,
Gygi S.P.;
"Large-scale characterization of HeLa cell nuclear phosphoproteins.";
Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004).
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[9]
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X-RAY CRYSTALLOGRAPHY (2.9 ANGSTROMS) OF 622-1231 ALONE AND IN COMPLEX WITH PHOSPHOPEPTIDE.
DOI=10.1084/jem.20041890; PubMed=15684325 [NCBI, ExPASy, EBI, Israel, Japan]
Nam H.J.,
Poy F.,
Saito H.,
Frederick C.A.;
"Structural basis for the function and regulation of the receptor protein tyrosine phosphatase CD45.";
J. Exp. Med. 201:441-452(2005).
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[10]
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INVOLVEMENT IN MS SUSCEPTIBILITY.
DOI=10.1038/82659; PubMed=11101853 [NCBI, ExPASy, EBI, Israel, Japan]
Jacobsen M.,
Schweer D.,
Ziegler A.,
Gaber R.,
Schock S.,
Schwinzer R.,
Wonigeit K.,
Lindert R.-B.,
Kantarci O.,
Schaefer-Klein J.,
Schipper H.I.,
Oertel W.H.,
Heidenreich F.,
Weinshenker B.G.,
Sommer N.,
Hemmer B.;
"A point mutation in PTPRC is associated with the development of multiple sclerosis.";
Nat. Genet. 26:495-499(2000).
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[11]
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VARIANT T(-)B(+)NK(+)SCID 362-GLU-TYR-363 DEL, AND CHARACTERIZATION OF VARIANT T(-)B(+)NK(+)SCID 362-GLU-TYR-363 DEL.
PubMed=11145714 [NCBI, ExPASy, EBI, Israel, Japan]
Tchilian E.Z.,
Wallace D.L.,
Wells R.S.,
Flower D.R.,
Morgan G.,
Beverley P.C.L.;
"A deletion in the gene encoding the CD45 antigen in a patient with SCID.";
J. Immunol. 166:1308-1313(2001).
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[12]
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VARIANTS [LARGE SCALE ANALYSIS] ALA-228 AND ARG-863.
DOI=10.1126/science.1133427; PubMed=16959974 [NCBI, ExPASy, EBI, Israel, Japan]
Sjoeblom T.,
Jones S.,
Wood L.D.,
Parsons D.W.,
Lin J.,
Barber T.D.,
Mandelker D.,
Leary R.J.,
Ptak J.,
Silliman N.,
Szabo S.,
Buckhaults P.,
Farrell C.,
Meeh P.,
Markowitz S.D.,
Willis J.,
Dawson D.,
Willson J.K.V.,
Gazdar A.F., ![]()
Hartigan J.,
Wu L.,
Liu C.,
Parmigiani G.,
Park B.H.,
Bachman K.E.,
Papadopoulos N.,
Vogelstein B.,
Kinzler K.W.,
Velculescu V.E.;
"The consensus coding sequences of human breast and colorectal cancers.";
Science 314:268-274(2006).
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