ID   OMP_RAT                 Reviewed;         163 AA.
AC   P08523;
DT   01-AUG-1988, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   04-NOV-2008, entry version 64.
DE   RecName: Full=Olfactory marker protein;
DE   AltName: Full=Olfactory neuronal-specific protein;
GN   Name=Omp;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;
OC   Muroidea; Muridae; Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   MEDLINE=87175546; PubMed=3470751;
RA   Rogers K.E., Dasgupta P., Gubler U., Grillo M., Khew-Goodall Y.S.,
RA   Margolis F.L.;
RT   "Molecular cloning and sequencing of a cDNA for olfactory marker
RT   protein.";
RL   Proc. Natl. Acad. Sci. U.S.A. 84:1704-1708(1987).
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RX   MEDLINE=90046838; PubMed=2701951;
RA   Danciger E., Mettling C., Vidal M., Morris R., Margolis F.L.;
RT   "Olfactory marker protein gene: its structure and olfactory neuron-
RT   specific expression in transgenic mice.";
RL   Proc. Natl. Acad. Sci. U.S.A. 86:8565-8569(1989).
RN   [3]
RP   PROTEIN SEQUENCE OF 2-163.
RX   MEDLINE=86321994; PubMed=3753006; DOI=10.1016/0003-9861(86)90011-1;
RA   Sydor W., Teitelbaum Z., Blacher R., Sun S., Benz W., Margolis F.L.;
RT   "Amino acid sequence of a unique neuronal protein: rat olfactory
RT   marker protein.";
RL   Arch. Biochem. Biophys. 249:351-362(1986).
RN   [4]
RP   STRUCTURE BY NMR.
RX   MEDLINE=22050885; PubMed=12054873; DOI=10.1016/S0022-2836(02)00282-6;
RA   Baldisseri D.M., Margolis J.W., Weber D.J., Koo J.H., Margolis F.L.;
RT   "Olfactory marker protein (OMP) exhibits a beta-clam fold in solution:
RT   implications for target peptide interaction and olfactory signal
RT   transduction.";
RL   J. Mol. Biol. 319:823-837(2002).
CC   -!- FUNCTION: May act as a modulator of the olfactory signal-
CC       transduction cascade.
CC   -!- SUBUNIT: Interacts with BEX1 and BEX2 (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- TISSUE SPECIFICITY: Uniquely associated with mature olfactory
CC       receptor neurons.
CC   -!- SIMILARITY: Belongs to the olfactory marker protein family.
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DR   EMBL; M15644; AAA41757.1; -; mRNA.
DR   EMBL; M26926; AAA03054.1; -; Unassigned_DNA.
DR   PIR; A27450; A27450.
DR   RefSeq; NP_036748.1; -.
DR   UniGene; Rn.9720; -.
DR   PDB; 1JYT; NMR; -; A=1-163.
DR   PDB; 1ZRI; NMR; -; A=1-163.
DR   PDBsum; 1JYT; -.
DR   PDBsum; 1ZRI; -.
DR   DisProt; DP00279; -.
DR   GeneID; 24612; -.
DR   KEGG; rno:24612; -.
DR   RGD; 3231; Omp.
DR   HOVERGEN; P08523; -.
DR   NextBio; 603848; -.
DR   GO; GO:0005515; F:protein binding; IDA:MGI.
DR   InterPro; IPR009103; Olfactory_marker.
DR   Gene3D; G3DSA:2.60.120.390; Olfactory_marker; 1.
DR   PANTHER; PTHR15357; Olfactory_marker; 1.
DR   Pfam; PF06554; Olfactory_mark; 1.
DR   ProDom; PD022055; Olfactory_marker; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Acetylation; Cytoplasm; Direct protein sequencing;
KW   Olfaction; Sensory transduction.
FT   INIT_MET      1      1       Removed.
FT   CHAIN         2    163       Olfactory marker protein.
FT                                /FTId=PRO_0000058046.
FT   MOD_RES       2      2       N-acetylalanine.
FT   STRAND        4      8
FT   HELIX        19     33
FT   TURN         36     38
FT   STRAND       53     56
FT   STRAND       69     71
FT   STRAND       73     81
FT   TURN         89     91
FT   STRAND       97     99
FT   STRAND      103    109
FT   TURN        110    112
FT   STRAND      113    118
FT   HELIX       119    134
FT   STRAND      138    144
FT   STRAND      155    157
SQ   SEQUENCE   163 AA;  18853 MW;  3E04155D1154199E CRC64;
     MAEDGPQKQQ LDMPLVLDQD LTKQMRLRVE SLKQRGEKKQ DGEKLLRPAE SVYRLDFIQQ
     QKLQFDHWNV VLDKPGKVTI TGTSQNWTPD LTNLMTRQLL DPAAIFWRKE DSDAMDWNEA
     DALEFGERLS DLAKIRKVMY FLITFGEGVE PANLKASVVF NQL
//