ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry P08431


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name GAL7_YEAST
Primary accession number P08431
Secondary accession number P04398
Integrated into Swiss-Prot on March 20, 1987
Sequence was last modified on January 23, 2007 (Sequence version 4)
Annotations were last modified on    November 4, 2008 (Entry version 85)
Name and origin of the protein
Protein name Galactose-1-phosphate uridylyltransferase
Synonyms Gal-1-P uridylyltransferase
EC 2.7.7.12
UDP-glucose--hexose-1-phosphate uridylyltransferase
Gene name
Name: GAL7
OrderedLocusNames: YBR018C
ORFNames: YBR0226
From
Saccharomyces cerevisiae (Baker's yeast) [TaxID: 4932] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces.
Protein existence 1: Evidence at protein level;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
PubMed=2851900 [NCBI, ExPASy, EBI, Israel, Japan]
Tajima M., Nogi Y., Fukasawa T.;
"Primary structure of the Saccharomyces cerevisiae GAL7 gene.";
Yeast 1:67-77(1985).
[2]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=ATCC 204508 / S288c;
PubMed=7762304 [NCBI, ExPASy, EBI, Israel, Japan]
Schaaff-Gerstenschlaeger I., Schindwolf T., Lehnert W., Rose M., Zimmermann F.K.;
"Sequence and functional analysis of a 7.2 kb fragment of Saccharomyces cerevisiae chromosome II including GAL7 and GAL10 and a new essential open reading frame.";
Yeast 11:79-83(1995).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 204508 / S288c;
PubMed=7813418 [NCBI, ExPASy, EBI, Israel, Japan]
Feldmann H., Aigle M., Aljinovic G., Andre B., Baclet M.C., Barthe C., Baur A., Becam A.-M., Biteau N., Boles E., Brandt T., Brendel M., Brueckner M., Bussereau F., Christiansen C., Contreras R., Crouzet M., Cziepluch C., Demolis N., Delaveau T., Doignon F., Domdey H., Duesterhus S., Dubois E., Dujon B., El Bakkoury M., Entian K.-D., Feuermann M., Fiers W., Fobo G.M., Fritz C., Gassenhuber J., Glansdorff N., Goffeau A., Grivell L.A., de Haan M., Hein C., Herbert C.J., Hollenberg C.P., Holmstroem K., Jacq C., Jacquet M., Jauniaux J.-C., Jonniaux J.-L., Kallesoee T., Kiesau P., Kirchrath L., Koetter P., Korol S., Liebl S., Logghe M., Lohan A.J.E., Louis E.J., Li Z.Y., Maat M.J., Mallet L., Mannhaupt G., Messenguy F., Miosga T., Molemans F., Mueller S., Nasr F., Obermaier B., Perea J., Pierard A., Piravandi E., Pohl F.M., Pohl T.M., Potier S., Proft M., Purnelle B., Ramezani Rad M., Rieger M., Rose M., Schaaff-Gerstenschlaeger I., Scherens B., Schwarzlose C., Skala J., Slonimski P.P., Smits P.H.M., Souciet J.-L., Steensma H.Y., Stucka R., Urrestarazu L.A., van der Aart Q.J.M., Van Dyck L., Vassarotti A., Vetter I., Vierendeels F., Vissers S., Wagner G., de Wergifosse P., Wolfe K.H., Zagulski M., Zimmermann F.K., Mewes H.-W., Kleine K.;
"Complete DNA sequence of yeast chromosome II.";
EMBO J. 13:5795-5809(1994).
[4]
NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-185.
STRAIN=Carlsbergensis;
PubMed=6715281 [NCBI, ExPASy, EBI, Israel, Japan]
Citron B.A., Donelson J.E.;
"Sequence of the Saccharomyces GAL region and its transcription in vivo.";
J. Bacteriol. 158:269-278(1984).
[5]
NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-21, AND PROTEIN SEQUENCE OF 2-8.
DOI=10.1093/nar/11.24.8555; PubMed=6324089 [NCBI, ExPASy, EBI, Israel, Japan]
Nogi Y., Fukasawa T.;
"Nucleotide sequence of the transcriptional initiation region of the yeast GAL7 gene.";
Nucleic Acids Res. 11:8555-8568(1983).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
X81324; CAA57105.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
M12348; AAA34627.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
X00215; CAA25039.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
Z35887; CAA84960.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
K01752; AAA34628.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR S45873; XNBYUG.
RefSeq NP_009574.1; -.
3D structure databases
HSSP P09148; 1HXP. [HSSP ENTRY / PDB]
ModBase P08431.
Protein-protein interaction databases
DIP DIP:5357N; -.
IntAct P08431; -.
Organism-specific databases
CYGD YBR018c; -.
SGD S000000222; GAL7.
Yeast-GFP YBR018C.
Gene expression databases
GermOnline YBR018C; Saccharomyces cerevisiae.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from direct assay from SGD).
GO:0008108; Molecular function: UDP-glucose:hexose-1-phosphate uridylyltransferase activity (inferred from direct assay from SGD).
GO:0033499; Biological process: galactose catabolic process via UDP-galactose (inferred from direct assay from SGD).
QuickGo view.
Family and domain databases
InterPro IPR001937; GalP_UDPtransf1.
IPR005850; GalP_Utransf_C.
IPR005849; GalP_Utransf_N.
IPR011151; His_triad_motif.
Graphical view of domain structure.
Gene3D G3DSA:3.30.428.10; His_triad_motif; 2.
PANTHER PTHR11943; GalP_UDPtransf1; 1.
Pfam PF02744; GalP_UDP_tr_C; 1.
PF01087; GalP_UDP_transf; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000808; GalT; 1.
ProDom PD005051; GalP_Utransf; 2.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR00209; galT_1; 1.
PROSITE PS00117; GAL_P_UDP_TRANSF_I; 1.
BLOCKS P08431.
ProtoNet P08431.
Proteomic databases
PeptideAtlas P08431; -.
Genome annotation databases
Ensembl YBR018C; Saccharomyces cerevisiae. [Contig view]
GeneID 852306; -.
GenomeReviews Y13134_GR; YBR018C.
KEGG sce:YBR018C; -.
NMPDR fig|4932.3.peg.269; -.
Phylogenomic databases
HOGENOM P08431; -.
Other
LinkHub P08431; -.
NextBio 970978; -.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Carbohydrate metabolism; Complete proteome; Direct protein sequencing; Galactose metabolism; Iron; Metal-binding; Nucleotidyltransferase; Transferase; Zinc.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
INIT_MET   1     1        Removed. 
CHAIN   2   366  365     Galactose-1-phosphate uridylyltransferase. PRO_0000169893
ACT_SITE   182   182        Tele-UMP-histidine intermediate (By similarity). 
METAL   54    54        Zinc (By similarity). 
METAL   57    57        Zinc (By similarity). 
METAL   124   124        Zinc (By similarity). 
METAL   180   180        Zinc (By similarity). 
METAL   198   198        Iron (By similarity). 
METAL   297   297        Iron (By similarity). 
METAL   314   314        Iron (By similarity). 
METAL   316   316        Iron (By similarity). 
CONFLICT   11    11        H -> Y (in Ref. 4; AAA34628). 
CONFLICT   58    58        P -> H (in Ref. 4; AAA34628). 
CONFLICT   85    86        RL -> S (in Ref. 1; AAA34627). 
CONFLICT   267   267        V -> A (in Ref. 1; AAA34627). 
CONFLICT   345   345        T -> I (in Ref. 1; AAA34627). 
Sequence information
Length: 366 AA [This is the length of the unprocessed precursor] Molecular weight: 42385 Da [This is the MW of the unprocessed precursor] CRC64: 960F75532D2621DC [This is a checksum on the sequence]
        10         20         30         40         50         60 
MTAEEFDFSS HSHRRYNPLT DSWILVSPHR AKRPWLGQQE AAYKPTAPLY DPKCYLCPGN 

        70         80         90        100        110        120 
KRATGNLNPR YESTYIFPND YAAVRLDQPI LPQNDSNEDN LKNRLLKVQS VRGNCFVICF 

       130        140        150        160        170        180 
SPNHNLTIPQ MKQSDLVHIV NSWQALTDDL SREARENHKP FKYVQIFENK GTAMGCSNLH 

       190        200        210        220        230        240 
PHGQAWCLES IPSEVSQELK SFDKYKREHN TDLFADYVKL ESREKSRVVV ENESFIVVVP 

       250        260        270        280        290        300 
YWAIWPFETL VISKKKLASI SQFNQMVKED LASILKQLTI KYDNLFETSF PYSMGIHQAP 

       310        320        330        340        350        360 
LNATGDELSN SWFHMHFYPP LLRSATVRKF LVGFELLGEP QRDLTSEQAA EKLRNLDGQI 


HYLQRL 

P08431 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA)
Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
 Hosted by ch flag SIB Switzerland Mirror sites: Australia  Brazil  Canada  China  Korea
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!