NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=BE-81;
PubMed=3667527 [NCBI, ExPASy, EBI, Israel, Japan]
Irie S., Doi S., Yorifuji T., Takagi M., Yano K.;
"Nucleotide sequencing and characterization of the genes encoding benzene oxidation enzymes of Pseudomonas putida.";
J. Bacteriol. 169:5174-5179(1987).

Comments

CATALYTIC ACTIVITY: Cis-1,2-dihydrobenzene-1,2-diol + NAD⁺ = catechol + NADH.
PATHWAY: Aromatic compound metabolism; benzene degradation; catechol from benzene: step 2/2 .
SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

M17904; AAA25739.1; ALT_INIT; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

PIR

E36516; E36516.

3D structure databases

HSSP

P47227; 1BDB. [HSSP ENTRY / PDB]

ModBase

P08088.

Ontologies

GO:0018504;	Molecular function: cis-1,2-dihydrobenzene-1,2-diol dehydrogenase activity (inferred from electronic annotation from EC).
GO:0019439;	Biological process: aromatic compound catabolic process (inferred from electronic annotation from UniProtKB-KW).
GO:0055114;	Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.

Family and domain databases

InterPro

IPR017711; BphB_TodD.
IPR002198; DHase_sc/Rdtase_SDR.
IPR002347; Glc/ribitol_DHase.
Graphical view of domain structure.

PANTHER

PTHR19410; ADH_short_C2; 1.

Pfam

PF00106; adh_short; 1.
Pfam graphical view of domain structure.

PRINTS

PR00081; GDHRDH.
PR00080; SDRFAMILY.

PROSITE

PS00061; ADH_SHORT; 1.

Other

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Aromatic hydrocarbons catabolism; NAD; Oxidoreductase.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 275`	`275`	`Cis-1,2-dihydrobenzene-1,2-diol dehydrogenase.`	`PRO_0000054530`
`NP_BIND`	`9 33`	`25`	`NAD (By similarity).`
`ACT_SITE`	`155 155`		`Proton acceptor (By similarity).`
`BINDING`	`142 142`		`Substrate (By similarity).`

Sequence information

Length: 275 AA [This is the length of the unprocessed precursor]

Molecular weight: 28782 Da [This is the MW of the unprocessed precursor]

CRC64: D5919208D859234B [This is a checksum on the sequence]

        10         20         30         40         50         60 
MRLEGEVALV TGGGAGLGRA IVDRYVAEGA RVAVLDKSAA GLEALRKLHG DAIVGVEGDV 

        70         80         90        100        110        120 
RSLDSHREAV ARCVEAFGKL DCLVGNAGVW DYLTQLVDIP DDLISEAFEE MFEVNVKGYI 

       130        140        150        160        170        180 
LAAKAALPAL YQSKGSAIFT VSNAGFYPGG GGVLYTAGKH AVIGLIKQLA HEWGPRIRVN 

       190        200        210        220        230        240 
GIAPGGILGS DLRGLKSLDL QDKSISTFPL DDMLKSVLPT GRAATAEEYA GAYVFFATRG 

       250        260        270 
DTVPLTGSVL NFDGGMGVRG LFEASLGAQL DKHFG

P08088 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools