[1]
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NUCLEOTIDE SEQUENCE [MRNA], AND PROTEIN SEQUENCE OF 31-56; 446-453; 503-524; 561-579; 668-672 AND 721-729.
TISSUE=Placenta;
PubMed=2877871 [NCBI, ExPASy, EBI, Israel, Japan]
Ullrich A.,
Gray A.,
Tam A.W.,
Yang-Feng T.,
Tsubokawa M.,
Collins C.,
Henzel W.,
Bon T.L.,
Kathuria S.,
Chen E.,
Jacobs S.,
Francke U.,
Ramachandran J.,
Fujita-Yamaguchi Y.;
"Insulin-like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity.";
EMBO J. 5:2503-2512(1986).
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[2]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA].
PubMed=1316909 [NCBI, ExPASy, EBI, Israel, Japan]
Abbot A.M.,
Bueno R.,
Pedrini M.T.,
Murray J.M.,
Smith R.J.;
"Insulin-like growth factor I receptor gene structure.";
J. Biol. Chem. 267:10759-10763(1992).
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[3]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND VARIANTS MET-388 AND HIS-605.
Rieder M.J.,
Livingston R.J.,
Daniels M.R.,
Montoya M.A.,
Chung M.-W.,
Miyamoto K.E.,
Nguyen C.P.,
Nguyen D.A.,
Poel C.L.,
Robertson P.D.,
Schackwitz W.S.,
Sherwood J.K.,
Witrak L.A.,
Nickerson D.A.;
"NIEHS-SNPs, environmental genome project, NIEHS ES15478, Department of Genome Sciences, Seattle, WA (URL: http://egp.gs.washington.edu).";
Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
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[4]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
TISSUE=Cerebellum;
DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan]
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
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[5]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-31.
DOI=10.1016/0006-291X(91)90654-P; PubMed=1711844 [NCBI, ExPASy, EBI, Israel, Japan]
Cooke D.W.,
Bankert L.A.,
Roberts C.T. Jr.,
Leroith D.,
Casella S.J.;
"Analysis of the human type I insulin-like growth factor receptor promoter region.";
Biochem. Biophys. Res. Commun. 177:1113-1120(1991).
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[6]
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NUCLEOTIDE SEQUENCE [MRNA] OF 1137-1193, AND TISSUE SPECIFICITY.
TISSUE=Melanocyte;
PubMed=8247543 [NCBI, ExPASy, EBI, Israel, Japan]
Lee S.-T.,
Strunk K.M.,
Spritz R.A.;
"A survey of protein tyrosine kinase mRNAs expressed in normal human melanocytes.";
Oncogene 8:3403-3410(1993).
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[7]
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FUNCTION, SUBUNIT, AND AUTOPHOSPHORYLATION.
DOI=10.1021/bi00215a008; PubMed=1846292 [NCBI, ExPASy, EBI, Israel, Japan]
Tollefsen S.E.,
Stoszek R.M.,
Thompson K.;
"Interaction of the alpha beta dimers of the insulin-like growth factor I receptor is required for receptor autophosphorylation.";
Biochemistry 30:48-54(1991).
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[8]
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FUNCTION, CATALYTIC ACTIVITY, AND AUTOPHOSPHORYLATION.
PubMed=7679099 [NCBI, ExPASy, EBI, Israel, Japan]
Kato H.,
Faria T.N.,
Stannard B.,
Roberts C.T. Jr.,
LeRoith D.;
"Role of tyrosine kinase activity in signal transduction by the insulin-like growth factor-I (IGF-I) receptor. Characterization of kinase-deficient IGF-I receptors and the action of an IGF-I-mimetic antibody (alpha IR-3).";
J. Biol. Chem. 268:2655-2661(1993).
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[9]
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INTERACTION WITH IRS1; SHC1 AND PIK3R1, AND MUTAGENESIS OF TYR-980 AND LYS-1033.
DOI=10.1074/jbc.270.26.15639; PubMed=7541045 [NCBI, ExPASy, EBI, Israel, Japan]
Craparo A.,
O'Neill T.J.,
Gustafson T.A.;
"Non-SH2 domains within insulin receptor substrate-1 and SHC mediate their phosphotyrosine-dependent interaction with the NPEY motif of the insulin-like growth factor I receptor.";
J. Biol. Chem. 270:15639-15643(1995).
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[10]
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AUTOPHOSPHORYLATION.
DOI=10.1006/bbrc.2000.4046; PubMed=11162456 [NCBI, ExPASy, EBI, Israel, Japan]
Lopaczynski W.,
Terry C.,
Nissley P.;
"Autophosphorylation of the insulin-like growth factor I receptor cytoplasmic domain.";
Biochem. Biophys. Res. Commun. 279:955-960(2000).
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[11]
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VARIANTS IGF1 RESISTANCE GLN-138 AND ASN-145, AND CHARACTERIZATION OF VARIANTS IGF1 RESISTANCE GLN-138 AND ASN-145.
DOI=10.1056/NEJMoa010107; PubMed=14657428 [NCBI, ExPASy, EBI, Israel, Japan]
The intrauterine growth retardation (IUGR) study group;
Abuzzahab M.J.,
Schneider A.,
Goddard A.,
Grigorescu F.,
Lautier C.,
Keller E.,
Kiess W.,
Klammt J.,
Kratzsch J.,
Osgood D.,
Pfaeffle R.,
Raile K.,
Seidel B.,
Smith R.J.,
Chernausek S.D.;
"IGF-I receptor mutations resulting in intrauterine and postnatal growth retardation.";
N. Engl. J. Med. 349:2211-2222(2003).
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[12]
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VARIANT IGF1 RESISTANCE GLN-739, AND CHARACTERIZATION OF VARIANT IGF1 RESISTANCE GLN-739.
DOI=10.1210/jc.2004-1947; PubMed=15928254 [NCBI, ExPASy, EBI, Israel, Japan]
Kawashima Y.,
Kanzaki S.,
Yang F.,
Kinoshita T.,
Hanaki K.,
Nagaishi J.,
Ohtsuka Y.,
Hisatome I.,
Ninomoya H.,
Nanba E.,
Fukushima T.,
Takahashi S.;
"Mutation at cleavage site of insulin-like growth factor receptor in a short-stature child born with intrauterine growth retardation.";
J. Clin. Endocrinol. Metab. 90:4679-4687(2005).
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[13]
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VARIANTS [LARGE SCALE ANALYSIS] LEU-105; HIS-437; HIS-595; SER-857; THR-1338 AND VAL-1347.
DOI=10.1038/nature05610; PubMed=17344846 [NCBI, ExPASy, EBI, Israel, Japan]
Greenman C.,
Stephens P.,
Smith R.,
Dalgliesh G.L.,
Hunter C.,
Bignell G.,
Davies H.,
Teague J.,
Butler A.,
Stevens C.,
Edkins S.,
O'Meara S.,
Vastrik I.,
Schmidt E.E.,
Avis T.,
Barthorpe S.,
Bhamra G.,
Buck G.,
Choudhury B., ![]()
Clements J.,
Cole J.,
Dicks E.,
Forbes S.,
Gray K.,
Halliday K.,
Harrison R.,
Hills K.,
Hinton J.,
Jenkinson A.,
Jones D.,
Menzies A.,
Mironenko T.,
Perry J.,
Raine K.,
Richardson D.,
Shepherd R.,
Small A.,
Tofts C.,
Varian J.,
Webb T.,
West S.,
Widaa S.,
Yates A.,
Cahill D.P.,
Louis D.N.,
Goldstraw P.,
Nicholson A.G.,
Brasseur F.,
Looijenga L.,
Weber B.L.,
Chiew Y.-E.,
DeFazio A.,
Greaves M.F.,
Green A.R.,
Campbell P.,
Birney E.,
Easton D.F.,
Chenevix-Trench G.,
Tan M.-H.,
Khoo S.K.,
Teh B.T.,
Yuen S.T.,
Leung S.Y.,
Wooster R.,
Futreal P.A.,
Stratton M.R.;
"Patterns of somatic mutation in human cancer genomes.";
Nature 446:153-158(2007).
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