[1]
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NUCLEOTIDE SEQUENCE [MRNA].
PubMed=3561390 [NCBI, ExPASy, EBI, Israel, Japan]
Yamanashi Y.,
Fukushige S.,
Semba K.,
Sukegawa J.,
Miyajima N.,
Matsubara K.,
Yamamoto T.,
Toyoshima K.;
"The yes-related cellular gene lyn encodes a possible tyrosine kinase similar to p56lck.";
Mol. Cell. Biol. 7:237-243(1987).
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[2]
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NUCLEOTIDE SEQUENCE [MRNA].
DOI=10.1016/0378-1119(94)90811-7; PubMed=8125304 [NCBI, ExPASy, EBI, Israel, Japan]
Rider L.G.,
Raben N.,
Miller L.,
Jelsema C.;
"The cDNAs encoding two forms of the LYN protein tyrosine kinase are expressed in rat mast cells and human myeloid cells.";
Gene 138:219-222(1994).
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[3]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM LYN A).
DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan]
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
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[4]
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NUCLEOTIDE SEQUENCE [MRNA] OF 369-424.
PubMed=2247464 [NCBI, ExPASy, EBI, Israel, Japan]
Partanen J.,
Maekelae T.P.,
Alitalo R.,
Lehvaeslaiho H.,
Alitalo K.;
"Putative tyrosine kinases expressed in K-562 human leukemia cells.";
Proc. Natl. Acad. Sci. U.S.A. 87:8913-8917(1990).
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[5]
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NUCLEOTIDE SEQUENCE [MRNA] OF 369-424.
DOI=10.1016/S0006-291X(05)81562-1; PubMed=1510669 [NCBI, ExPASy, EBI, Israel, Japan]
Bielke W.,
Ziemiecki A.,
Kappos L.,
Miescher G.C.;
"Expression of the B cell-associated tyrosine kinase gene Lyn in primary neuroblastoma tumours and its modulation during the differentiation of neuroblastoma cell lines.";
Biochem. Biophys. Res. Commun. 186:1403-1409(1992).
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[6]
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INTERACTION WITH EPSTEIN-BARR VIRUS LMP2A.
DOI=10.1016/S1074-7613(95)80040-9; PubMed=7895172 [NCBI, ExPASy, EBI, Israel, Japan]
Miller C.L.,
Burkhardt A.L.,
Lee J.H.,
Stealey B.,
Longnecker R.,
Bolen J.B.,
Kieff E.;
"Integral membrane protein 2 of Epstein-Barr virus regulates reactivation from latency through dominant negative effects on protein-tyrosine kinases.";
Immunity 2:155-166(1995).
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[7]
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INTERACTION WITH PPP1R15A.
DOI=10.1073/pnas.191130798; PubMed=11517336 [NCBI, ExPASy, EBI, Israel, Japan]
Grishin A.V.,
Azhipa O.,
Semenov I.,
Corey S.J.;
"Interaction between growth arrest-DNA damage protein 34 and Src kinase Lyn negatively regulates genotoxic apoptosis.";
Proc. Natl. Acad. Sci. U.S.A. 98:10172-10177(2001).
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[8]
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INTERACTION WITH MUC1.
PubMed=12750561 [NCBI, ExPASy, EBI, Israel, Japan]
Li Y.,
Chen W.,
Ren J.,
Yu W.H.,
Li Q.,
Yoshida K.,
Kufe D.;
"DF3/MUC1 signaling in multiple myeloma cells is regulated by interleukin-7.";
Cancer Biol. Ther. 2:187-193(2003).
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[9]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-508, AND MASS SPECTROMETRY.
DOI=10.1038/nbt1046; PubMed=15592455 [NCBI, ExPASy, EBI, Israel, Japan]
Rush J.,
Moritz A.,
Lee K.A.,
Guo A.,
Goss V.L.,
Spek E.J.,
Zhang H.,
Zha X.-M.,
Polakiewicz R.D.,
Comb M.J.;
"Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.";
Nat. Biotechnol. 23:94-101(2005).
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[10]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-11 AND TYR-508, AND MASS SPECTROMETRY.
TISSUE=Epithelium;
DOI=10.1016/j.cell.2006.09.026; PubMed=17081983 [NCBI, ExPASy, EBI, Israel, Japan]
Olsen J.V.,
Blagoev B.,
Gnad F.,
Macek B.,
Kumar C.,
Mortensen P.,
Mann M.;
"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.";
Cell 127:635-648(2006).
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[11]
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INTERACTION WITH TGFB1I1.
DOI=10.1042/BJ20061618; PubMed=17233630 [NCBI, ExPASy, EBI, Israel, Japan]
Rathore V.B.,
Okada M.,
Newman P.J.,
Newman D.K.;
"Paxillin family members function as Csk-binding proteins that regulate Lyn activity in human and murine platelets.";
Biochem. J. 403:275-281(2007).
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[12]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-193; TYR-194; TYR-306; TYR-397; TYR-473 AND TYR-508, AND MASS SPECTROMETRY.
DOI=10.1016/j.cell.2007.11.025; PubMed=18083107 [NCBI, ExPASy, EBI, Israel, Japan]
Rikova K.,
Guo A.,
Zeng Q.,
Possemato A.,
Yu J.,
Haack H.,
Nardone J.,
Lee K.,
Reeves C.,
Li Y.,
Hu Y.,
Tan Z.,
Stokes M.,
Sullivan L.,
Mitchell J.,
Wetzel R.,
Macneill J.,
Ren J.M.,
Yuan J., ![]()
Bakalarski C.E.,
Villen J.,
Kornhauser J.M.,
Smith B.,
Li D.,
Zhou X.,
Gygi S.P.,
Gu T.-L.,
Polakiewicz R.D.,
Rush J.,
Comb M.J.;
"Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer.";
Cell 131:1190-1203(2007).
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[13]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-13, AND MASS SPECTROMETRY.
DOI=10.1074/mcp.T600062-MCP200; PubMed=17192257 [NCBI, ExPASy, EBI, Israel, Japan]
Wissing J.,
Jaensch L.,
Nimtz M.,
Dieterich G.,
Hornberger R.,
Keri G.,
Wehland J.,
Daub H.;
"Proteomics analysis of protein kinases by target class-selective prefractionation and tandem mass spectrometry.";
Mol. Cell. Proteomics 6:537-547(2007).
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[14]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-13 AND TYR-397, AND MASS SPECTROMETRY.
TISSUE=Platelet;
DOI=10.1021/pr0704130; PubMed=18088087 [NCBI, ExPASy, EBI, Israel, Japan]
Zahedi R.P.,
Lewandrowski U.,
Wiesner J.,
Wortelkamp S.,
Moebius J.,
Schuetz C.,
Walter U.,
Gambaryan S.,
Sickmann A.;
"Phosphoproteome of resting human platelets.";
J. Proteome Res. 7:526-534(2008).
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[15]
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VARIANT [LARGE SCALE ANALYSIS] TYR-385.
DOI=10.1038/nature05610; PubMed=17344846 [NCBI, ExPASy, EBI, Israel, Japan]
Greenman C.,
Stephens P.,
Smith R.,
Dalgliesh G.L.,
Hunter C.,
Bignell G.,
Davies H.,
Teague J.,
Butler A.,
Stevens C.,
Edkins S.,
O'Meara S.,
Vastrik I.,
Schmidt E.E.,
Avis T.,
Barthorpe S.,
Bhamra G.,
Buck G.,
Choudhury B., ![]()
Clements J.,
Cole J.,
Dicks E.,
Forbes S.,
Gray K.,
Halliday K.,
Harrison R.,
Hills K.,
Hinton J.,
Jenkinson A.,
Jones D.,
Menzies A.,
Mironenko T.,
Perry J.,
Raine K.,
Richardson D.,
Shepherd R.,
Small A.,
Tofts C.,
Varian J.,
Webb T.,
West S.,
Widaa S.,
Yates A.,
Cahill D.P.,
Louis D.N.,
Goldstraw P.,
Nicholson A.G.,
Brasseur F.,
Looijenga L.,
Weber B.L.,
Chiew Y.-E.,
DeFazio A.,
Greaves M.F.,
Green A.R.,
Campbell P.,
Birney E.,
Easton D.F.,
Chenevix-Trench G.,
Tan M.-H.,
Khoo S.K.,
Teh B.T.,
Yuen S.T.,
Leung S.Y.,
Wooster R.,
Futreal P.A.,
Stratton M.R.;
"Patterns of somatic mutation in human cancer genomes.";
Nature 446:153-158(2007).
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