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- FUNCTION: Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.
- CATALYTIC ACTIVITY: ATP + creatine = ADP + phosphocreatine.
- SUBUNIT: Dimer of identical or non-identical chains. With MM being the major form in skeletal muscle and myocardium, MB existing in myocardium, and BB existing in many tissues, especially brain.
- SUBCELLULAR LOCATION: Cytoplasm.
- SIMILARITY: Belongs to the ATP:guanido phosphotransferase family.
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Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms.
Distributed under the Creative Commons Attribution-NoDerivs License.
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| Length: 381 AA [This is the length of the unprocessed precursor] |
Molecular weight: 43045 Da [This is the MW of the unprocessed precursor] |
CRC64: B573FEB1D2A41056 [This is a checksum on the sequence] |
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10 20 30 40 50 60
MPFGNTHNKF KLNYKPQEEY PDLSKHNNHM AKVLTPDLYN KLRDKETPSG FTLDDVIQTG
70 80 90 100 110 120
VDNPGHPFIM TVGCVAGDEE SYTVFKDLFD PIIQDRHGGY KPTDKHKTDL NHENLKGGDD
130 140 150 160 170 180
LDPNYVLSSR VRTGRSIKGY TLPPHCSRGE RRAVEKLSVE ALNSLTGEFK GKYYPLKSMT
190 200 210 220 230 240
EQEQQQLIDD HFLFDKPVSP LLLASGMARD WPDARGIWHN DNKSFLVWVN EEDHLRVISM
250 260 270 280 290 300
EKGGNMKEVF RRFCVGLQKI EEIFKKAGHP FMWNEHLGYV LTCPSNLGTG LRGGVHVKLA
310 320 330 340 350 360
NLSKHPKFEE ILTRLRLQKR GTGGVDTAAV GAVFDISNAD RLGSSEVEQV QLVVDGVKLM
370 380
VEMEKKLEKG QSIDDMIPAQ K
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P07310 in FASTA format |
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