ID   BGLS_HANAN              Reviewed;         825 AA.
AC   P06835;
DT   01-JAN-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1988, sequence version 1.
DT   04-NOV-2008, entry version 50.
DE   RecName: Full=Beta-glucosidase;
DE            EC=3.2.1.21;
DE   AltName: Full=Gentiobiase;
DE   AltName: Full=Cellobiase;
DE   AltName: Full=Beta-D-glucoside glucohydrolase;
DE   Flags: Precursor;
OS   Hansenula anomala (Yeast) (Candida pelliculosa).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
OC   Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Pichia.
OX   NCBI_TaxID=4927;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Acetaetherius;
RX   MEDLINE=86016087; PubMed=2995925; DOI=10.1093/nar/13.17.6273;
RA   Kohchi C., Toh-e A.;
RT   "Nucleotide sequence of Candida pelliculosa beta-glucosidase gene.";
RL   Nucleic Acids Res. 13:6273-6282(1985).
CC   -!- CATALYTIC ACTIVITY: Hydrolysis of terminal, non-reducing beta-D-
CC       glucose residues with release of beta-D-glucose.
CC   -!- PATHWAY: Glycan metabolism; cellulose degradation.
CC   -!- SUBUNIT: Homotetramer.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 3 family.
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DR   EMBL; X02903; CAA26662.1; -; Genomic_DNA.
DR   PIR; B23783; GLHQ.
DR   GO; GO:0008422; F:beta-glucosidase activity; IEA:EC.
DR   GO; GO:0030245; P:cellulose catabolic process; IEA:UniProtKB-KW.
DR   InterPro; IPR002772; Glyco_hydro_3_C.
DR   InterPro; IPR001764; Glyco_hydro_3_N.
DR   Gene3D; G3DSA:3.20.20.300; Glyco_hydro_3_N; 1.
DR   Pfam; PF00933; Glyco_hydro_3; 1.
DR   Pfam; PF01915; Glyco_hydro_3_C; 1.
DR   PRINTS; PR00133; GLHYDRLASE3.
DR   PROSITE; PS00775; GLYCOSYL_HYDROL_F3; 1.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism; Cellulose degradation; Glycoprotein;
KW   Glycosidase; Hydrolase; Polysaccharide degradation; Signal.
FT   SIGNAL        1     20       Potential.
FT   CHAIN        21    825       Beta-glucosidase.
FT                                /FTId=PRO_0000011777.
FT   ACT_SITE    299    299       By similarity.
FT   CARBOHYD     21     21       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD     34     34       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD     74     74       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD     97     97       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD    230    230       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD    271    271       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD    328    328       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD    335    335       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD    537    537       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD    550    550       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD    556    556       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD    578    578       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD    605    605       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD    667    667       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD    690    690       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD    718    718       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD    733    733       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD    761    761       N-linked (GlcNAc...) (Potential).
SQ   SEQUENCE   825 AA;  89561 MW;  A43852FF3DE58B74 CRC64;
     MLLPLYGLAS FLVLSQAALV NTSAPQASND DPFNHSPSFY PTPQGGRIND GKWQAAFYRA
     RELVDQMSIA EKVNLTTGVG SASGPCSGNT GSVPRLNISS ICVQDGPLSV RAADLTDVFP
     CGMAASSSFN KQLIYDRAVA IGSEFKGKGA DAILGPVYGP MGVKAAGGRG WEGHGPDPYL
     EGVIAYLQTI GIQSQGVVST AKHLIGNEQE HFRFAKKDKH AGKIDPGMFN TSSSLSSEID
     DRAMHEIYLW PFAEAVRGGV SSIMCSYNKL NGSHACQNSY LLNYLLKEEL GFQGFVMTDW
     GALYSGIDAA NAGLDMDMPC EAQYFGGNLT TAVLNGTLPQ DRLDDMATRI LSALIYSGVH
     NPDGPNYNAQ TFLTEGHEYF KQQEGDIVVL NKHVDVRSDI NRAVALRSAV EGVVLLKNEH
     ETLPLGREKV KRISILGQAA GDDSKGTSCS LRGCGSGAIG TGYGSGAGTF SYFVTPADGI
     GARAQQEKIS YEFIGDSWNQ AAAMDSALYA DAAIEVANSV AGEEIGDVDG NYGDLNNLTL
     WHNAVPLIKN ISSINNNTIV IVTSGQQIDL EPFIDNENVT AVIYSSYLGQ DFGTVLAKVL
     FGDENPSGKL PFTIAKDVND YIPVIEKVDV PDPVDKFTES IYVDYRYFDK YNKPVRYEFG
     YGLSYSNFSL SDIEIQTLQP FSENAEPAAN YSETYQYKQS NMDPSEYTVP EGFKELANYT
     YPYIHDASSI KANSSYDYPE GYSTEQLDGP KSLAAGGLGG NHTCGMLVTL SLLKSQIKVL
     MLVGLHLNCM LDIQIMMNSQ HLQCNYVDLK RCFWIKIILK LFLLN
//