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UniProtKB/Swiss-Prot entry P06758


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ADH2_ZYMMO
Primary accession number P06758
Secondary accession number Q5NM40
Integrated into Swiss-Prot on January 1, 1988
Sequence was last modified on January 23, 2007 (Sequence version 3)
Annotations were last modified on    November 4, 2008 (Entry version 56)
Name and origin of the protein
Protein name Alcohol dehydrogenase 2
Synonyms EC 1.1.1.1
Alcohol dehydrogenase II
ADH II
Gene name
Name: adhB
OrderedLocusNames: ZMO1596
From
Zymomonas mobilis [TaxID: 542] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Alphaproteobacteria; Sphingomonadales; Sphingomonadaceae; Zymomonas.
Protein existence 1: Evidence at protein level;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
PubMed=3584063 [NCBI, ExPASy, EBI, Israel, Japan]
Conway T., Sewell G.W., Osman Y.A., Ingram L.O.;
"Cloning and sequencing of the alcohol dehydrogenase II gene from Zymomonas mobilis.";
J. Bacteriol. 169:2591-2597(1987).
[2]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=ATCC 10988 / NCIB 8938 / NRRL B-806 / ZM1;
DOI=10.1093/nar/18.1.187; PubMed=2308827 [NCBI, ExPASy, EBI, Israel, Japan]
Yoon K.-H., Pack M.Y.;
"Nucleotide sequence of the Zymomonas mobilis alcohol dehydrogenase II gene.";
Nucleic Acids Res. 18:187-187(1990).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 31821 / ZM4 / CP4;
DOI=10.1038/nbt1045; PubMed=15592456 [NCBI, ExPASy, EBI, Israel, Japan]
Seo J.-S., Chong H., Park H.S., Yoon K.-O., Jung C., Kim J.J., Hong J.H., Kim H., Kim J.-H., Kil J.-I., Park C.J., Oh H.-M., Lee J.-S., Jin S.-J., Um H.-W., Lee H.-J., Oh S.-J., Kim J.Y., Kang H.L., Lee S.Y., Lee K.J., Kang H.S.;
"The genome sequence of the ethanologenic bacterium Zymomonas mobilis ZM4.";
Nat. Biotechnol. 23:63-68(2005).
[4]
PROTEIN SEQUENCE OF 2-50.
DOI=10.1111/j.1432-1033.1986.tb09366.x; PubMed=2935393 [NCBI, ExPASy, EBI, Israel, Japan]
Neale A.D., Scopes R.K., Kelly J.M., Wettenhall R.E.H.;
"The two alcohol dehydrogenases of Zymomonas mobilis. Purification by differential dye ligand chromatography, molecular characterisation and physiological roles.";
Eur. J. Biochem. 154:119-124(1986).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
M15394; AAA27683.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
X17065; CAA34911.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AE008692; AAV90220.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR A25978; A25978.
RefSeq YP_163331.1; -.
3D structure databases
ModBase P06758.
Enzyme and pathway databases
BioCyc ZMOB264203:ZMO1596-MON; -.
Ontologies
GO
GO:0004022; Molecular function: alcohol dehydrogenase activity (inferred from electronic annotation from EC).
GO:0005506; Molecular function: iron ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR001670; Fe_AlcDHase.
Graphical view of domain structure.
Pfam PF00465; Fe-ADH; 1.
Pfam graphical view of domain structure.
PROSITE PS00913; ADH_IRON_1; 1.
PS00060; ADH_IRON_2; 1.
BLOCKS P06758.
ProtoNet P06758.
Genome annotation databases
GeneID 3187659; -.
GenomeReviews AE008692_GR; ZMO1596.
KEGG zmo:ZMO1596; -.
NMPDR fig|264203.3.peg.70; -.
Phylogenomic databases
HOGENOM P06758; -.
Genome annotation databases
CMR P06758; ZMO1596.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Direct protein sequencing; Iron; NAD; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom  To Length Description FTId
INIT_MET   1     1        Removed. 
CHAIN   2   383  382     Alcohol dehydrogenase 2. PRO_0000087815
CONFLICT   38    38        S -> G (in Ref. 4; AA sequence). 
CONFLICT   45    48        SGVV -> GVS (in Ref. 4; AA sequence). 
CONFLICT   57    57        A -> T (in Ref. 2; CAA34911). 
Sequence information
Length: 383 AA [This is the length of the unprocessed precursor] Molecular weight: 40145 Da [This is the MW of the unprocessed precursor] CRC64: E1C3A159B1652342 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MASSTFYIPF VNEMGEGSLE KAIKDLNGSG FKNALIVSDA FMNKSGVVKQ VADLLKAQGI 

        70         80         90        100        110        120 
NSAVYDGVMP NPTVTAVLEG LKILKDNNSD FVISLGGGSP HDCAKAIALV ATNGGEVKDY 

       130        140        150        160        170        180 
EGIDKSKKPA LPLMSINTTA GTASEMTRFC IITDEVRHVK MAIVDRHVTP MVSVNDPLLM 

       190        200        210        220        230        240 
VGMPKGLTAA TGMDALTHAF EAYSSTAATP ITDACALKAA SMIAKNLKTA CDNGKDMPAR 

       250        260        270        280        290        300 
EAMAYAQFLA GMAFNNASLG YVHAMAHQLG GYYNLPHGVC NAVLLPHVLA YNASVVAGRL 

       310        320        330        340        350        360 
KDVGVAMGLD IANLGDKEGA EATIQAVRDL AASIGIPANL TELGAKKEDV PLLADHALKD 

       370        380 
ACALTNPRQG DQKEVEELFL SAF 

P06758 in FASTA format

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