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UniProtKB/Swiss-Prot entry P06593


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name PHYA3_AVESA
Primary accession number P06593
Secondary accession numbers None
Integrated into Swiss-Prot on January 1, 1988
Sequence was last modified on January 23, 2007 (Sequence version 3)
Annotations were last modified on    July 22, 2008 (Entry version 78)
Name and origin of the protein
Protein name Phytochrome A type 3
Synonym AP3
Gene name
Name: PHYA3
Synonyms: PHY3
From
Avena sativa (Oat) [TaxID: 4498] 
Taxonomy Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; Liliopsida; Poales; Poaceae; BEP clade; Pooideae; Aveneae; Avena.
Protein existence 1: Evidence at protein level;
References
[1]
NUCLEOTIDE SEQUENCE [MRNA].
DOI=10.1093/nar/13.23.8543; PubMed=3001642 [NCBI, ExPASy, EBI, Israel, Japan]
Hershey H.P., Barker R.F., Idler K.B., Lissemore J.L., Quail P.H.;
"Analysis of cloned cDNA and genomic sequences for phytochrome: complete amino acid sequences for two gene products expressed in etiolated Avena.";
Nucleic Acids Res. 13:8543-8559(1985).
[2]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
DOI=10.1016/0378-1119(87)90197-1; PubMed=2965664 [NCBI, ExPASy, EBI, Israel, Japan]
Hershey H.P., Barker R.F., Idler K.B., Murray M.G., Quail P.H.;
"Nucleotide sequence and characterization of a gene encoding the phytochrome polypeptide from Avena.";
Gene 61:339-348(1987).
[3]
PROTEIN SEQUENCE OF 2-13.
Grimm R., Kellermann J., Schaefer W., Ruediger W.;
"The amino-terminal structure of oat phytochrome.";
FEBS Lett. 234:497-499(1988).
Comments
  • FUNCTION: Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light: the Pr form that absorbs maximally in the red region of the spectrum and the Pfr form that absorbs maximally in the far-red region. Photoconversion of Pr to Pfr induces an array of morphogenic responses, whereas reconversion of Pfr to Pr cancels the induction of those responses. Pfr controls the expression of a number of nuclear genes including those encoding the small subunit of ribulose-bisphosphate carboxylase, chlorophyll A/B binding protein, protochlorophyllide reductase, rRNA, etc. It also controls the expression of its own gene(s) in a negative feedback fashion.
  • SUBUNIT: Homodimer.
  • INTERACTION:
    Q9SL63:At2g20180 (xeno); NbExp=1; IntAct=EBI-630413, EBI-630400;
  • PTM: Contains one covalently linked phytochromobilin chromophore.
  • SIMILARITY: Belongs to the phytochrome family.
  • SIMILARITY: Contains 1 GAF domain.
  • SIMILARITY: Contains 1 histidine kinase domain.
  • SIMILARITY: Contains 2 PAS (PER-ARNT-SIM) domains.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
X03242; CAA26999.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
M18822; AAA76820.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR A29631; A29631.
3D structure databases
ModBase P06593.
Protein-protein interaction databases
IntAct P06593; -.
Organism-specific databases
Gramene P06593; -.
Ontologies
GO
GO:0005515; Molecular function: protein binding (inferred from physical interaction from IntAct).
QuickGo view.
Family and domain databases
InterPro IPR003594; ATP_bd_ATPase.
IPR003018; GAF.
IPR000014; PAS.
IPR013654; PAS_2.
IPR013767; PAS_fold.
IPR016132; Phyto_chromo_attachment.
IPR013516; Phyto_chromo_BS.
IPR001294; Phytochrome.
IPR012129; Phytochrome_A-E.
IPR013515; Phytochrome_Cr.
IPR003661; Sig_transdc_His_kin_sub1_dim/P.
IPR005467; Sig_transdc_His_kinase_core.
Graphical view of domain structure.
Gene3D G3DSA:3.30.565.10; ATP_bd_ATPase; 1.
Pfam PF01590; GAF; 1.
PF02518; HATPase_c; 1.
PF00512; HisKA; 1.
PF00989; PAS; 2.
PF08446; PAS_2; 1.
PF00360; Phytochrome; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000084; Phytochrome; 1.
PRINTS PR01033; PHYTOCHROME.
SMART SM00065; GAF; 1.
SM00387; HATPase_c; 1.
SM00388; HisKA; 1.
SM00091; PAS; 2.
SMART graphical view of domain structure.
TIGRFAMs TIGR00229; sensory_box; 1.
PROSITE PS50109; HIS_KIN; 1.
PS50112; PAS; 2.
PS00245; PHYTOCHROME_1; 1.
PS50046; PHYTOCHROME_2; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS P06593.
ProtoNet P06593.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Chromophore; Direct protein sequencing; Photoreceptor protein; Receptor; Repeat; Sensory transduction; Transcription; Transcription regulation.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
INIT_MET   1      1        Removed. 
CHAIN   2   1129  1128     Phytochrome A type 3. PRO_0000171967
DOMAIN   217    402  186     GAF. 
DOMAIN   618    688  71     PAS 1. 
DOMAIN   748    822  75     PAS 2. 
DOMAIN   902   1122  221     Histidine kinase. 
BINDING   322    322        Phytochromobilin chromophore (covalent; via 1 link). 
CONFLICT   279    279        L -> F (in Ref. 2; AAA76820). 
Sequence information
Length: 1129 AA [This is the length of the unprocessed precursor] Molecular weight: 124993 Da [This is the MW of the unprocessed precursor] CRC64: 8AC1083533567ACF [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSSSRPASSS SSRNRQSSQA RVLAQTTLDA ELNAEYEESG DSFDYSKLVE AQRDGPPVQQ 

        70         80         90        100        110        120 
GRSEKVIAYL QHIQKGKLIQ TFGCLLALDE KSFNVIAFSE NAPEMLTTVS HAVPSVDDPP 

       130        140        150        160        170        180 
RLGIGTNVRS LFSDQGATAL HKALGFADVS LLNPILVQCK TSGKPFYAIV HRATGCLVVD 

       190        200        210        220        230        240 
FEPVKPTEFP ATAAGALQSY KLAAKAISKI QSLPGGSMEV LCNTVVKEVF DLTGYDRVMA 

       250        260        270        280        290        300 
YKFHEDDHGE VFSEITKPGL EPYLGLHYPA TDIPQAARLL FMKNKVRMIC DCRARSIKVI 

       310        320        330        340        350        360 
EAEALPFDIS LCGSALRAPH SCHLQYMENM NSIASLVMAV VVNENEEDDE AESEQPAQQQ 

       370        380        390        400        410        420 
KKKKLWGLLV CHHESPRYVP FPLRYACEFL AQVFAVHVNR EFELEKQLRE KNILKMQTML 

       430        440        450        460        470        480 
SDMLFREASP LTIVSGTPNI MDLVKCDGAA LLYGGKVWRL RNAPTESQIH DIAFWLSDVH 

       490        500        510        520        530        540 
RDSTGLSTDS LHDAGYPGAA ALGDMICGMA VAKINSKDIL FWFRSHTAAE IRWGGAKNDP 

       550        560        570        580        590        600 
SDMDDSRRMH PRLSFKAFLE VVKMKSLPWS DYEMDAIHSL QLILRGTLND ASKPKREASL 

       610        620        630        640        650        660 
DNQIGDLKLD GLAELQAVTS EMVRLMETAT VPILAVDGNG LVNGWNQKAA ELTGLRVDDA 

       670        680        690        700        710        720 
IGRHILTLVE DSSVPVVQRM LYLALQGKEE KEVRFEVKTH GPKRDDGPVI LVVNACASRD 

       730        740        750        760        770        780 
LHDHVVGVCF VAQDMTVHKL VMDKFTRVEG DYKAIIHNPN PLIPPIFGAD EFGWCSEWNA 

       790        800        810        820        830        840 
AMTKLTGWNR DEVLDKMLLG EVFDSSNASC PLKNRDAFVS LCVLINSALA GEETEKAPFG 

       850        860        870        880        890        900 
FFDRSGKYIE CLLSANRKEN EGGLITGVFC FIHVASHELQ HALQVQQASE QTSLKRLKAF 

       910        920        930        940        950        960 
SYMRHAINNP LSGMLYSRKA LKNTDLNEEQ MKQIHVGDNC HHQINKILAD LDQDSITEKS 

       970        980        990       1000       1010       1020 
SCLDLEMAEF LLQDVVVAAV SQVLITCQGK GIRISCNLPE RFMKQSVYGD GVRLQQILSD 

      1030       1040       1050       1060       1070       1080 
FLFISVKFSP VGGSVEISSK LTKNSIGENL HLIDLELRIK HQGLGVPAEL MAQMFEEDNK 

      1090       1100       1110       1120 
EQSEEGLSLL VSRNLLRLMN GDVRHLREAG VSTFIITAEL ASAPTAMGQ 

P06593 in FASTA format

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View entry in raw text format (no links)
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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