[1]	NUCLEOTIDE SEQUENCE [GENOMIC DNA]. PubMed=3782013 [NCBI, ExPASy, EBI, Israel, Japan] Fukumori F., Sashihara N., Kudo T., Horikoshi K.; "Nucleotide sequences of two cellulase genes from alkalophilic Bacillus sp. strain N-4 and their strong homology."; J. Bacteriol. 168:479-485(1986).

Comments

CATALYTIC ACTIVITY: Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.
SIMILARITY: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

M14781; AAA22301.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

PIR

A25156; A25156.

3D structure databases

HSSP

Q59232; 1LF1. [HSSP ENTRY / PDB]

SMR

P06566; 28-328.

ModBase

P06566.

Ontologies

GO:0008810;	Molecular function: cellulase activity (inferred from electronic annotation from EC).
GO:0030245;	Biological process: cellulose catabolic process (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.

Family and domain databases

InterPro

IPR003610; CBM_5_12.
IPR001547; Glyco_hydro_5.
IPR013781; Glyco_hydro_sub_cat.
Graphical view of domain structure.

Gene3D

G3DSA:3.20.20.80; Glyco_hydro_cat; 1.

Pfam

PF02839; CBM_5_12; 2.
PF00150; Cellulase; 1.
Pfam graphical view of domain structure.

SMART

SM00495; ChtBD3; 2.
SMART graphical view of domain structure.

PROSITE

PS00659; GLYCOSYL_HYDROL_F5; 1.

Other

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Carbohydrate metabolism; Cellulose degradation; Glycosidase; Hydrolase; Polysaccharide degradation.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 488`	`488`	`Endoglucanase A.`	`PRO_0000184044`
`ACT_SITE`	`163 163`		`Proton donor (By similarity).`
`ACT_SITE`	`252 252`		`Nucleophile (By similarity).`

Sequence information

Length: 488 AA [This is the length of the unprocessed precursor]

Molecular weight: 54264 Da [This is the MW of the unprocessed precursor]

CRC64: 97248E453D28D3B5 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MKKLTTIFIV FTLALLFVGN STSANNGSVV EQNGQLSIQN GQLVNEHGDP VQLKGMSSHG 

        70         80         90        100        110        120 
LQWYGQFVNY DSIKWLRDDW GITVFRAAMY TSSGGYIEDP SVKEKVKEAV EAAIDLGIYV 

       130        140        150        160        170        180 
IIDWHILSDN DPNIYKEEAK EFFDEMSALY GDYPNVIYEI ANEPNGHNVR WDSHIKPYAE 

       190        200        210        220        230        240 
EVIPVIRAND PNNIVIVGTA TWSQDVHEAA DNQLDDPNVM YAFHFYAGTH GQQLRNQVDY 

       250        260        270        280        290        300 
ALSRGAAIFV SEWGTSAATG DGGVFLDEAQ VWIDFMDERN LSWANWSLTH KDESSAALMP 

       310        320        330        340        350        360 
GANPTGGWTA AELSPSGAFV REKIRESASI PPSDPTPPSD PDPGEPDPTP PSDPGEYPAW 

       370        380        390        400        410        420 
DPNQIYTNEI VYHNGQLWQA KWWTQNQEPG ANQYGPWEPL GDAPPSEPSD PPPPSEPEPD 

       430        440        450        460        470        480 
PGEPDPGEPD PGEPDPTPPS DPGEYPAWDP TQIYTNEIVY HNGQLWQAKW WTQNQEPGYP 


YGPWEPLN

P06566 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools