[1]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=ATCC 10014 / CCUG 3716 / NCTC 8479;
PubMed=3549710 [NCBI, ExPASy, EBI, Israel, Japan]
Caserta M.,
Zacharias W.,
Nwankwo D.O.,
Wilson G.G.,
Wells R.D.;
"Cloning, sequencing, in vivo promoter mapping, and expression in Escherichia coli of the gene for the HhaI methyltransferase.";
J. Biol. Chem. 262:4770-4777(1987).
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[2]
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MUTAGENESIS.
DOI=10.1093/nar/21.10.2459; PubMed=8506140 [NCBI, ExPASy, EBI, Israel, Japan]
Mi S.,
Roberts R.J.;
"The DNA binding affinity of HhaI methylase is increased by a single amino acid substitution in the catalytic center.";
Nucleic Acids Res. 21:2459-2464(1993).
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[3]
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BIOPHYSICOCHEMICAL PROPERTIES, AND MUTAGENESIS OF GLN-237.
DOI=10.1093/nar/23.4.620; PubMed=7899082 [NCBI, ExPASy, EBI, Israel, Japan]
Mi S.,
Alonso D.,
Roberts R.J.;
"Functional analysis of Gln-237 mutants of HhaI methyltransferase.";
Nucleic Acids Res. 23:620-627(1995).
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[4]
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X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS).
DOI=10.1016/0092-8674(93)90421-L; PubMed=8343957 [NCBI, ExPASy, EBI, Israel, Japan]
Cheng X.,
Kumar S.,
Posfai J.,
Pflugrath J.W.,
Roberts R.J.;
"Crystal structure of the HhaI DNA methyltransferase complexed with S-adenosyl-L-methionine.";
Cell 74:299-307(1993).
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[5]
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X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS).
DOI=10.1016/0092-8674(94)90342-5; PubMed=8293469 [NCBI, ExPASy, EBI, Israel, Japan]
Klimasauskas S.,
Kumar S.,
Roberts R.J.,
Cheng X.;
"HhaI methyltransferase flips its target base out of the DNA helix.";
Cell 76:357-369(1994).
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[6]
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X-RAY CRYSTALLOGRAPHY (2.05 ANGSTROMS).
DOI=10.1093/nar/25.14.2773; PubMed=9207024 [NCBI, ExPASy, EBI, Israel, Japan]
Kumar S.,
Horton J.R.,
Jones G.D.,
Walker R.T.,
Roberts R.J.,
Cheng X.;
"DNA containing 4'-thio-2'-deoxycytidine inhibits methylation by HhaI methyltransferase.";
Nucleic Acids Res. 25:2773-2783(1997).
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[7]
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X-RAY CRYSTALLOGRAPHY (2.87 ANGSTROMS).
DOI=10.1038/2312; PubMed=9783745 [NCBI, ExPASy, EBI, Israel, Japan]
O'Gara M.,
Horton J.R.,
Roberts R.J.,
Cheng X.;
"Structures of HhaI methyltransferase complexed with substrates containing mismatches at the target base.";
Nat. Struct. Biol. 5:872-877(1998).
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[8]
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X-RAY CRYSTALLOGRAPHY (2.61 ANGSTROMS).
DOI=10.1006/jmbi.1999.2608; PubMed=10080885 [NCBI, ExPASy, EBI, Israel, Japan]
O'Gara M.,
Zhang X.,
Roberts R.J.,
Cheng X.;
"Structure of a binary complex of HhaI methyltransferase with S-adenosyl-L-methionine formed in the presence of a short non-specific DNA oligonucleotide.";
J. Mol. Biol. 287:201-209(1999).
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