[1]
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PRELIMINARY PROTEIN SEQUENCE.
DOI=10.1016/0014-5793(77)80757-6; PubMed=838078 [NCBI, ExPASy, EBI, Israel, Japan]
Kramps J.A.,
de Man B.M.,
de Jong W.W.;
"The primary structure of the B2 chain of human alpha-crystallin.";
FEBS Lett. 74:82-84(1977).
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[2]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA].
DOI=10.1016/0888-7543(90)90204-8; PubMed=2387586 [NCBI, ExPASy, EBI, Israel, Japan]
Dubin R.A.,
Ally A.H.,
Chung S.,
Piatigorsky J.;
"Human alpha B-crystallin gene and preferential promoter function in lens.";
Genomics 7:594-601(1990).
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[3]
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NUCLEOTIDE SEQUENCE [MRNA].
DOI=10.1016/0304-3940(92)90689-5; PubMed=1407707 [NCBI, ExPASy, EBI, Israel, Japan]
Iwaki A.,
Iwaki T.,
Goldman J.E.,
Ogomori K.,
Tateishi J.,
Sakaki Y.;
"Accumulation of alpha B-crystallin in brains of patients with Alexander's disease is not due to an abnormality of the 5'-flanking and coding sequence of the genomic DNA.";
Neurosci. Lett. 140:89-92(1992).
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[4]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Yu W.,
Sarginson J.,
Gibbs R.A.;
Submitted (JUN-1997) to the EMBL/GenBank/DDBJ databases.
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[5]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
DOI=10.1038/ng1285; PubMed=14702039 [NCBI, ExPASy, EBI, Israel, Japan]
Ota T.,
Suzuki Y.,
Nishikawa T.,
Otsuki T.,
Sugiyama T.,
Irie R.,
Wakamatsu A.,
Hayashi K.,
Sato H.,
Nagai K.,
Kimura K.,
Makita H.,
Sekine M.,
Obayashi M.,
Nishi T.,
Shibahara T.,
Tanaka T.,
Ishii S.,
Yamamoto J., ![]()
Saito K.,
Kawai Y.,
Isono Y.,
Nakamura Y.,
Nagahari K.,
Murakami K.,
Yasuda T.,
Iwayanagi T.,
Wagatsuma M.,
Shiratori A.,
Sudo H.,
Hosoiri T.,
Kaku Y.,
Kodaira H.,
Kondo H.,
Sugawara M.,
Takahashi M.,
Kanda K.,
Yokoi T.,
Furuya T.,
Kikkawa E.,
Omura Y.,
Abe K.,
Kamihara K.,
Katsuta N.,
Sato K.,
Tanikawa M.,
Yamazaki M.,
Ninomiya K.,
Ishibashi T.,
Yamashita H.,
Murakawa K.,
Fujimori K.,
Tanai H.,
Kimata M.,
Watanabe M.,
Hiraoka S.,
Chiba Y.,
Ishida S.,
Ono Y.,
Takiguchi S.,
Watanabe S.,
Yosida M.,
Hotuta T.,
Kusano J.,
Kanehori K.,
Takahashi-Fujii A.,
Hara H.,
Tanase T.-O.,
Nomura Y.,
Togiya S.,
Komai F.,
Hara R.,
Takeuchi K.,
Arita M.,
Imose N.,
Musashino K.,
Yuuki H.,
Oshima A.,
Sasaki N.,
Aotsuka S.,
Yoshikawa Y.,
Matsunawa H.,
Ichihara T.,
Shiohata N.,
Sano S.,
Moriya S.,
Momiyama H.,
Satoh N.,
Takami S.,
Terashima Y.,
Suzuki O.,
Nakagawa S.,
Senoh A.,
Mizoguchi H.,
Goto Y.,
Shimizu F.,
Wakebe H.,
Hishigaki H.,
Watanabe T.,
Sugiyama A.,
Takemoto M.,
Kawakami B.,
Yamazaki M.,
Watanabe K.,
Kumagai A.,
Itakura S.,
Fukuzumi Y.,
Fujimori Y.,
Komiyama M.,
Tashiro H.,
Tanigami A.,
Fujiwara T.,
Ono T.,
Yamada K.,
Fujii Y.,
Ozaki K.,
Hirao M.,
Ohmori Y.,
Kawabata A.,
Hikiji T.,
Kobatake N.,
Inagaki H.,
Ikema Y.,
Okamoto S.,
Okitani R.,
Kawakami T.,
Noguchi S.,
Itoh T.,
Shigeta K.,
Senba T.,
Matsumura K.,
Nakajima Y.,
Mizuno T.,
Morinaga M.,
Sasaki M.,
Togashi T.,
Oyama M.,
Hata H.,
Watanabe M.,
Komatsu T.,
Mizushima-Sugano J.,
Satoh T.,
Shirai Y.,
Takahashi Y.,
Nakagawa K.,
Okumura K.,
Nagase T.,
Nomura N.,
Kikuchi H.,
Masuho Y.,
Yamashita R.,
Nakai K.,
Yada T.,
Nakamura Y.,
Ohara O.,
Isogai T.,
Sugano S.;
"Complete sequencing and characterization of 21,243 full-length human cDNAs.";
Nat. Genet. 36:40-45(2004).
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[6]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Kalnine N.,
Chen X.,
Rolfs A.,
Halleck A.,
Hines L.,
Eisenstein S.,
Koundinya M.,
Raphael J.,
Moreira D.,
Kelley T.,
LaBaer J.,
Lin Y.,
Phelan M.,
Farmer A.;
"Cloning of human full-length CDSs in BD Creator(TM) system donor vector.";
Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
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[7]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA].
NHLBI resequencing and genotyping service (RS&G);
Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases.
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[8]
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NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Mural R.J.,
Istrail S.,
Sutton G.G.,
Florea L.,
Halpern A.L.,
Mobarry C.M.,
Lippert R.,
Walenz B.,
Shatkay H.,
Dew I.,
Miller J.R.,
Flanigan M.J.,
Edwards N.J.,
Bolanos R.,
Fasulo D.,
Halldorsson B.V.,
Hannenhalli S.,
Turner R.,
Yooseph S., ![]()
Lu F.,
Nusskern D.R.,
Shue B.C.,
Zheng X.H.,
Zhong F.,
Delcher A.L.,
Huson D.H.,
Kravitz S.A.,
Mouchard L.,
Reinert K.,
Remington K.A.,
Clark A.G.,
Waterman M.S.,
Eichler E.E.,
Adams M.D.,
Hunkapiller M.W.,
Myers E.W.,
Venter J.C.;
Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
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[9]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
TISSUE=Heart;
DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan]
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
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[10]
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PROTEIN SEQUENCE OF 2-24; 35-66 AND 118-175, AND ASSOCIATION WITH HSPB1.
TISSUE=Pectoralis muscle;
PubMed=1560006 [NCBI, ExPASy, EBI, Israel, Japan]
Kato K.,
Shinohara H.,
Goto S.,
Inaguma Y.,
Morishita R.,
Asano T.;
"Copurification of small heat shock protein with alpha B crystallin from human skeletal muscle.";
J. Biol. Chem. 267:7718-7725(1992).
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[11]
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PROTEIN SEQUENCE OF 57-66.
DOI=10.1074/jbc.272.4.2268; PubMed=8999933 [NCBI, ExPASy, EBI, Israel, Japan]
Lampi K.J.,
Ma Z.,
Shih M.,
Shearer T.R.,
Smith J.B.,
Smith D.L.,
David L.L.;
"Sequence analysis of betaA3, betaB3, and betaA4 crystallins completes the identification of the major proteins in young human lens.";
J. Biol. Chem. 272:2268-2275(1997).
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[12]
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PROTEIN SEQUENCE OF 83-89 AND 164-172.
TISSUE=Heart;
DOI=10.1002/elps.11501601192; PubMed=7498159 [NCBI, ExPASy, EBI, Israel, Japan]
Kovalyov L.I.,
Shishkin S.S.,
Efimochkin A.S.,
Kovalyova M.A.,
Ershova E.S.,
Egorov T.A.,
Musalyamov A.K.;
"The major protein expression profile and two-dimensional protein database of human heart.";
Electrophoresis 16:1160-1169(1995).
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[13]
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NUCLEOTIDE SEQUENCE [MRNA] OF 107-175.
DOI=10.1016/0092-8674(89)90173-6; PubMed=2539261 [NCBI, ExPASy, EBI, Israel, Japan]
Iwaki T.,
Kume-Iwaki A.,
Liem R.K.H.,
Goldman J.E.;
"Alpha B-crystallin is expressed in non-lenticular tissues and accumulates in Alexander's disease brain.";
Cell 57:71-78(1989).
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[14]
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RACEMIZATION/ISOMERIZATION OF SPECIFIC ASP.
DOI=10.1016/0167-4838(94)90003-5; PubMed=8142454 [NCBI, ExPASy, EBI, Israel, Japan]
Fujii N.,
Ishibashi Y.,
Satoh K.,
Fujino M.,
Harada K.;
"Simultaneous racemization and isomerization at specific aspartic acid residues in alpha B-crystallin from the aged human lens.";
Biochim. Biophys. Acta 1204:157-163(1994).
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[15]
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PHOSPHORYLATION AT SER-19; SER-45 AND SER-59, AND MASS SPECTROMETRY.
PubMed=8175657 [NCBI, ExPASy, EBI, Israel, Japan]
Miesbauer L.R.,
Zhou X.,
Yang Z.,
Yang Z.,
Sun Y.,
Smith D.L.,
Smith J.B.;
"Post-translational modifications of water-soluble human lens crystallins from young adults.";
J. Biol. Chem. 269:12494-12502(1994).
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[16]
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IDENTIFICATION AS A RENAL CANCER ANTIGEN.
TISSUE=Renal cell carcinoma;
DOI=10.1002/(SICI)1097-0215(19991112)83:4<456::AID-IJC4>3.0.CO;2-5; PubMed=10508479 [NCBI, ExPASy, EBI, Israel, Japan]
Scanlan M.J.,
Gordan J.D.,
Williamson B.,
Stockert E.,
Bander N.H.,
Jongeneel C.V.,
Gure A.O.,
Jaeger D.,
Jaeger E.,
Knuth A.,
Chen Y.-T.,
Old L.J.;
"Antigens recognized by autologous antibody in patients with renal-cell carcinoma.";
Int. J. Cancer 83:456-464(1999).
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[17]
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MASS SPECTROMETRY, SUSCEPTIBILITY TO OXIDATION, AND PHOSPHORYLATION.
DOI=10.1006/exer.2000.0868; PubMed=10930324 [NCBI, ExPASy, EBI, Israel, Japan]
Hanson S.R.A.,
Hasan A.,
Smith D.L.,
Smith J.B.;
"The major in vivo modifications of the human water-insoluble lens crystallins are disulfide bonds, deamidation, methionine oxidation and backbone cleavage.";
Exp. Eye Res. 71:195-207(2000).
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[18]
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INTERACTION WITH HSPBAP1.
DOI=10.1074/jbc.M001981200; PubMed=10751411 [NCBI, ExPASy, EBI, Israel, Japan]
Liu C.,
Gilmont R.R.,
Benndorf R.,
Welsh M.J.;
"Identification and characterization of a novel protein from Sertoli cells, PASS1, that associates with mammalian small stress protein hsp27.";
J. Biol. Chem. 275:18724-18731(2000).
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[19]
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PHOSPHORYLATION AT SER-45 AND SER-59.
DOI=10.1046/j.1471-4159.2001.00038.x; PubMed=11158243 [NCBI, ExPASy, EBI, Israel, Japan]
Kato K.,
Inaguma Y.,
Ito H.,
Iida K.,
Iwamoto I.,
Kamei K.,
Ochi N.,
Ohta H.,
Kishikawa M.;
"Ser-59 is the major phosphorylation site in alphaB-crystallin accumulated in the brains of patients with Alexander's disease.";
J. Neurochem. 76:730-736(2001).
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[20]
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ACETYLATION AT LYS-92.
DOI=10.1110/ps.40901; PubMed=11369851 [NCBI, ExPASy, EBI, Israel, Japan]
Lapko V.N.,
Smith D.L.,
Smith J.B.;
"In vivo carbamylation and acetylation of water-soluble human lens alphaB-crystallin lysine 92.";
Protein Sci. 10:1130-1136(2001).
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[21]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-19; SER-21; SER-43; SER-45; SER-53; SER-59 AND SER-76, METHYLATION AT ARG-22 AND ARG-50, ACETYLATION AT LYS-92, SUSCEPTIBILITY TO OXIDATION, AND MASS SPECTROMETRY.
DOI=10.1073/pnas.122231399; PubMed=12060738 [NCBI, ExPASy, EBI, Israel, Japan]
MacCoss M.J.,
McDonald W.H.,
Saraf A.,
Sadygov R.,
Clark J.M.,
Tasto J.J.,
Gould K.L.,
Wolters D.,
Washburn M.,
Weiss A.,
Clark J.I.,
Yates J.R. III;
"Shotgun identification of protein modifications from protein complexes and lens tissue.";
Proc. Natl. Acad. Sci. U.S.A. 99:7900-7905(2002).
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[22]
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INVOLVEMENT IN ALPHA-B CRYSTALLINOPATHY.
DOI=10.1002/ana.10767; PubMed=14681890 [NCBI, ExPASy, EBI, Israel, Japan]
Selcen D.,
Engel A.G.;
"Myofibrillar myopathy caused by novel dominant negative alpha B-crystallin mutations.";
Ann. Neurol. 54:804-810(2003).
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[23]
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INTERACTION WITH TTN.
DOI=10.1074/jbc.M307473200; PubMed=14676215 [NCBI, ExPASy, EBI, Israel, Japan]
Bullard B.,
Ferguson C.,
Minajeva A.,
Leake M.C.,
Gautel M.,
Labeit D.,
Ding L.,
Labeit S.,
Horwitz J.,
Leonard K.R.,
Linke W.A.;
"Association of the chaperone alphaB-crystallin with titin in heart muscle.";
J. Biol. Chem. 279:7917-7924(2004).
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[24]
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VARIANT ALPHA-B CRYSTALLINOPATHY GLY-120.
DOI=10.1038/1765; PubMed=9731540 [NCBI, ExPASy, EBI, Israel, Japan]
Vicart P.,
Caron A.,
Guicheney P.,
Li Z.,
Prevost M.-C.,
Faure A.,
Chateau D.,
Chapon F.,
Tome F.,
Dupret J.-M.,
Paulin D.,
Fardeau M.;
"A missense mutation in the alphaB-crystallin chaperone gene causes a desmin-related myopathy.";
Nat. Genet. 20:92-95(1998).
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[25]
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CHARACTERIZATION OF VARIANTS ALPHA-B CRYSTALLINOPATHY GLY-120.
DOI=10.1167/iovs.02-0950; PubMed=12601044 [NCBI, ExPASy, EBI, Israel, Japan]
Fu L.,
Liang J.J.-N.;
"Alteration of protein-protein interactions of congenital cataract crystallin mutants.";
Invest. Ophthalmol. Vis. Sci. 44:1155-1159(2003).
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