[1]	PROTEIN SEQUENCE. Dreyer W.J., Gray W.R., Hood L.E.; "The genetic, molecular, and cellular basis of antibody formation: some facts and a unifying hypothesis."; Cold Spring Harb. Symp. Quant. Biol. 32:353-367(1967).

Comments

INTERACTION:
P22392:NME2; NbExp=1; IntAct=EBI-1053880, EBI-713693;
MISCELLANEOUS: The C region of this chain has the INV (3) marker.
MISCELLANEOUS: This is a Bence-Jones protein.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

PIR

A01887; K2HUML.

3D structure databases

HSSP

Q99M37; 1I9I. [HSSP ENTRY / PDB]

SMR

P01616; 1-110.

ModBase

P01616.

Protein-protein interaction databases

IntAct

P01616; -.

Organism-specific databases

GeneCards

P01616.

Ontologies

GO:0005515;	Molecular function: protein binding (inferred from physical interaction from IntAct).
QuickGo view.

Family and domain databases

InterPro

IPR007110; Ig-like.
IPR013783; Ig-like_fold.
IPR013106; Ig_V-set.
IPR003596; Ig_V-set_sub.
Graphical view of domain structure.

Gene3D

G3DSA:2.60.40.10; Ig-like_fold; 1.

Pfam

PF07686; V-set; 1.
Pfam graphical view of domain structure.

SMART

SM00406; IGv; 1.
SMART graphical view of domain structure.

PROSITE

PS50835; IG_LIKE; 1.
PROSITE graphical view of domain structure (profiles).

Proteomic databases

P01616; -.

Phylogenomic databases

HOVERGEN

P01616; -.

Other

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Bence-Jones protein; Direct protein sequencing; Immunoglobulin domain; Immunoglobulin V region.

Features

Feature table viewer

Feature aligner

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 >112`	`>112`	`Ig kappa chain V-II region MIL.`	`PRO_0000059760`
`REGION`	`1 23`	`23`	`Framework-1.`
`REGION`	`24 38`	`15`	`Complementarity-determining-1.`
`REGION`	`39 53`	`15`	`Framework-2.`
`REGION`	`54 60`	`7`	`Complementarity-determining-2.`
`REGION`	`61 92`	`32`	`Framework-3.`
`REGION`	`93 101`	`9`	`Complementarity-determining-3.`
`REGION`	`102 111`	`10`	`Framework-4.`
`DISULFID`	`23 92`		`By similarity.`
`NON_TER`	`112 112`

Sequence information

Length: 112 AA [This is the length of the unprocessed precursor]

Molecular weight: 12057 Da [This is the MW of the unprocessed precursor]

CRC64: E5B22E2FA7ABE481 [This is a checksum on the sequence]

        10         20         30         40         50         60 
DIVLTQSPLS LPVTPGEPAS ISCRSSQNLL ZSBGBYLDWY LZKPGZSPZL LIYLGSNRAS 

        70         80         90        100        110 
GVPNRFSGSG SGTBFTLKIS RVZAZBVGVY YCMQALQTPL TFGGGTNVEI KR

P01616 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools