[1]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA].
PubMed=3555974 [NCBI, ExPASy, EBI, Israel, Japan]
Nedospasov S.A.,
Shakhov A.N.,
Turetskaya R.L.,
Mett V.A.,
Azizov M.M.,
Georgiev G.P.,
Korobko V.G.,
Dobrynin V.N.,
Filippov S.A.,
Bystrov N.S.,
Boldyreva E.F.,
Chuvpilo S.A.,
Chumakov A.M.,
Shingarova L.N.,
Ovchinnikov Y.A.;
"Tandem arrangement of genes coding for tumor necrosis factor (TNF-alpha) and lymphotoxin (TNF-beta) in the human genome.";
Cold Spring Harb. Symp. Quant. Biol. 51:611-624(1986).
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[2]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
DOI=10.1038/312724a0; PubMed=6392892 [NCBI, ExPASy, EBI, Israel, Japan]
Pennica D.,
Nedwin G.E.,
Hayflick J.S.,
Seeburg P.H.,
Derynck R.,
Palladino M.A.,
Kohr W.J.,
Aggarwal B.B.,
Goeddel D.V.;
"Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin.";
Nature 312:724-729(1984).
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[3]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
DOI=10.1038/313803a0; PubMed=3883195 [NCBI, ExPASy, EBI, Israel, Japan]
Shirai T.,
Yamaguchi H.,
Ito H.,
Todd C.W.,
Wallace R.B.;
"Cloning and expression in Escherichia coli of the gene for human tumour necrosis factor.";
Nature 313:803-806(1985).
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[4]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
DOI=10.1093/nar/13.17.6361; PubMed=2995927 [NCBI, ExPASy, EBI, Israel, Japan]
Nedwin G.E.,
Naylor S.L.,
Sakaguchi A.Y.,
Smith D.H.,
Jarrett-Nedwin J.,
Pennica D.,
Goeddel D.V.,
Gray P.W.;
"Human lymphotoxin and tumor necrosis factor genes: structure, homology and chromosomal localization.";
Nucleic Acids Res. 13:6361-6373(1985).
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[5]
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NUCLEOTIDE SEQUENCE [MRNA].
DOI=10.1126/science.3856324; PubMed=3856324 [NCBI, ExPASy, EBI, Israel, Japan]
Wang A.M.,
Creasey A.A.,
Ladner M.B.,
Lin L.S.,
Strickler J.,
van Arsdell J.N.,
Yamamoto R.,
Mark D.F.;
"Molecular cloning of the complementary DNA for human tumor necrosis factor.";
Science 228:149-154(1985).
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[6]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA].
DOI=10.1111/j.1432-1033.1985.tb09226.x; PubMed=3932069 [NCBI, ExPASy, EBI, Israel, Japan]
Marmenout A.,
Fransen L.,
Tavernier J.,
van der Heyden J.,
Tizard R.,
Kawashima E.,
Shaw A.,
Johnson M.J.,
Semon D.,
Mueller R.,
Ruysschaert M.-R.,
van Vliet A.,
Fiers W.;
"Molecular cloning and expression of human tumor necrosis factor and comparison with mouse tumor necrosis factor.";
Eur. J. Biochem. 152:515-522(1985).
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[7]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA].
DOI=10.1038/ng0293-137; PubMed=8499947 [NCBI, ExPASy, EBI, Israel, Japan]
Iris F.J.M.,
Bougueleret L.,
Prieur S.,
Caterina D.,
Primas G.,
Perrot V.,
Jurka J.,
Rodriguez-Tome P.,
Claverie J.-M.,
Dausset J.,
Cohen D.;
"Dense Alu clustering and a potential new member of the NF kappa B family within a 90 kilobase HLA class III segment.";
Nat. Genet. 3:137-145(1993).
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[8]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA].
PubMed=10202016 [NCBI, ExPASy, EBI, Israel, Japan]
Neville M.J.,
Campbell R.D.;
"A new member of the Ig superfamily and a V-ATPase G subunit are among the predicted products of novel genes close to the TNF locus in the human MHC.";
J. Immunol. 162:4745-4754(1999).
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[9]
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NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1101/gr.1736803; PubMed=14656967 [NCBI, ExPASy, EBI, Israel, Japan]
Xie T.,
Rowen L.,
Aguado B.,
Ahearn M.E.,
Madan A.,
Qin S.,
Campbell R.D.,
Hood L.;
"Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse.";
Genome Res. 13:2621-2636(2003).
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[10]
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NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Shiina S.,
Tamiya G.,
Oka A.,
Inoko H.;
"Homo sapiens 2,229,817bp genomic DNA of 6p21.3 HLA class I region.";
Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases.
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[11]
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NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Shiina T.,
Ota M.,
Katsuyama Y.,
Hashimoto N.,
Inoko H.;
"Genome diversity in HLA: a new strategy for detection of genetic polymorphisms in expressed genes within the HLA class III and class I regions.";
Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases.
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[12]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA].
SeattleSNPs variation discovery resource;
Submitted (DEC-2001) to the EMBL/GenBank/DDBJ databases.
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[13]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND VARIANT LEU-84.
NIEHS SNPs program;
Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases.
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[14]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
TISSUE=Blood;
DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan] The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
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[15]
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PROTEIN SEQUENCE OF 77-99, AND GLYCOSYLATION AT SER-80.
DOI=10.1111/j.1432-1033.1996.00431.x; PubMed=8631363 [NCBI, ExPASy, EBI, Israel, Japan]
Takakura-Yamamoto R.,
Yamamoto S.,
Fukuda S.,
Kurimoto M.;
"O-glycosylated species of natural human tumor-necrosis factor-alpha.";
Eur. J. Biochem. 235:431-437(1996).
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[16]
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NUCLEOTIDE SEQUENCE [MRNA] OF 77-233.
Jang J.S.,
Kim B.E.;
Submitted (JAN-1998) to the EMBL/GenBank/DDBJ databases.
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[17]
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NUCLEOTIDE SEQUENCE [MRNA] OF 84-214.
TISSUE=Prostatic carcinoma;
Shao C.,
Yan W.,
Zhu F.,
Yue W.,
Chai Y.,
Zhao Z.,
Wang C.;
Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases.
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[18]
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PHOSPHORYLATION (MEMBRANE FORM).
PubMed=8597870 [NCBI, ExPASy, EBI, Israel, Japan]
Pocsik E.,
Duda E.,
Wallach D.;
"Phosphorylation of the 26 kDa TNF precursor in monocytic cells and in transfected HeLa cells.";
J. Inflamm. 45:152-160(1995).
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[19]
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PHOSPHORYLATION BY CK1, AND DEPHOSPHORYLATION.
DOI=10.1093/emboj/18.8.2119; PubMed=10205166 [NCBI, ExPASy, EBI, Israel, Japan]
Watts A.D.,
Hunt N.H.,
Wanigasekara Y.,
Bloomfield G.,
Wallach D.,
Roufogalis B.D.,
Chaudhri G.;
"A casein kinase I motif present in the cytoplasmic domain of members of the tumour necrosis factor ligand family is implicated in 'reverse signalling'.";
EMBO J. 18:2119-2126(1999).
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[20]
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MUTAGENESIS.
PubMed=2009860 [NCBI, ExPASy, EBI, Israel, Japan]
Ostade X.V.,
Tavernier J.,
Prange T.,
Fiers W.;
"Localization of the active site of human tumour necrosis factor (hTNF) by mutational analysis.";
EMBO J. 10:827-836(1991).
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[21]
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MYRISTOYLATION AT LYS-19 AND LYS-20.
DOI=10.1084/jem.176.4.1053; PubMed=1402651 [NCBI, ExPASy, EBI, Israel, Japan]
Stevenson F.T.,
Bursten S.L.,
Locksley R.M.,
Lovett D.H.;
"Myristyl acylation of the tumor necrosis factor alpha precursor on specific lysine residues.";
J. Exp. Med. 176:1053-1062(1992).
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[22]
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CLEAVAGE BY ADAM17.
DOI=10.1038/385733a0; PubMed=9034191 [NCBI, ExPASy, EBI, Israel, Japan]
Moss M.L.,
Jin S.-L.C.,
Milla M.E.,
Burkhart W.,
Carter H.L.,
Chen W.-J.,
Clay W.C.,
Didsbury J.R.,
Hassler D.,
Hoffman C.R.,
Kost T.A.,
Lambert M.H.,
Leesnitzer M.A.,
McCauley P.,
McGeehan G.,
Mitchell J.,
Moyer M.,
Pahel G.,
Rocque W.,
Overton L.K.,
Schoenen F.,
Seaton T.,
Su J.-L.,
Warner J.,
Willard D.,
Becherer J.D.;
"Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-alpha.";
Nature 385:733-736(1997).
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[23]
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X-RAY CRYSTALLOGRAPHY (2.9 ANGSTROMS).
DOI=10.1038/338225a0; PubMed=2922050 [NCBI, ExPASy, EBI, Israel, Japan]
Jones E.Y.,
Stuart D.I.,
Walker N.P.;
"Structure of tumour necrosis factor.";
Nature 338:225-228(1989).
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[24]
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X-RAY CRYSTALLOGRAPHY (2.9 ANGSTROMS).
PubMed=1964681 [NCBI, ExPASy, EBI, Israel, Japan]
Jones E.Y.,
Stuart D.I.,
Walker N.P.;
"The structure of tumour necrosis factor -- implications for biological function.";
J. Cell Sci. Suppl. 13:11-18(1990).
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[25]
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X-RAY CRYSTALLOGRAPHY (2.6 ANGSTROMS).
PubMed=2551905 [NCBI, ExPASy, EBI, Israel, Japan]
Eck M.J.,
Sprang S.R.;
"The structure of tumor necrosis factor-alpha at 2.6-A resolution. Implications for receptor binding.";
J. Biol. Chem. 264:17595-17605(1989).
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[26]
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X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS) OF MUTANT ARG-107.
DOI=10.1093/protein/10.10.1101; PubMed=9488135 [NCBI, ExPASy, EBI, Israel, Japan]
Reed C.,
Fu Z.Q.,
Wu J.,
Xue Y.N.,
Harrison R.W.,
Chen M.J.,
Weber I.T.;
"Crystal structure of TNF-alpha mutant R31D with greater affinity for receptor R1 compared with R2.";
Protein Eng. 10:1101-1107(1997).
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[27]
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X-RAY CRYSTALLOGRAPHY (1.8 ANGSTROMS) OF MUTANT SER-3.
DOI=10.1074/jbc.273.4.2153; PubMed=9442056 [NCBI, ExPASy, EBI, Israel, Japan]
Cha S.S.,
Kim J.S.,
Cho H.S.,
Shin N.K.,
Jeong W.,
Shin H.C.,
Kim Y.J.,
Hahn J.H.,
Oh B.H.;
"High resolution crystal structure of a human tumor necrosis factor-alpha mutant with low systemic toxicity.";
J. Biol. Chem. 273:2153-2160(1998).
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[28]
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INVOLVEMENT IN PSORIATIC ARTHRITIS SUSCEPTIBILITY.
DOI=10.1002/art.10935; PubMed=12746914 [NCBI, ExPASy, EBI, Israel, Japan]
Balding J.,
Kane D.,
Livingstone W.,
Mynett-Johnson L.,
Bresnihan B.,
Smith O.,
FitzGerald O.;
"Cytokine gene polymorphisms: association with psoriatic arthritis susceptibility and severity.";
Arthritis Rheum. 48:1408-1413(2003).
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[29]
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INVOLVEMENT IN SUSCEPTIBILITY TO HBV INFECTION.
DOI=10.1093/hmg/ddg262; PubMed=12915457 [NCBI, ExPASy, EBI, Israel, Japan]
Kim Y.J.,
Lee H.-S.,
Yoon J.-H.,
Kim C.Y.,
Park M.H.,
Kim L.H.,
Park B.L.,
Shin H.D.;
"Association of TNF-alpha promoter polymorphisms with the clearance of hepatitis B virus infection.";
Hum. Mol. Genet. 12:2541-2546(2003).
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