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UniProtKB/Swiss-Prot entry P00570

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name KAD1_BOVIN
Primary accession number P00570
Secondary accession number Q5E9G9
Integrated into Swiss-Prot on July 21, 1986
Sequence was last modified on June 27, 2006 (Sequence version 2)
Annotations were last modified on    July 22, 2008 (Entry version 62)
Name and origin of the protein
Protein name Adenylate kinase isoenzyme 1
Synonyms AK 1
EC 2.7.4.3
ATP-AMP transphosphorylase 1
Myokinase
Gene name
Name: AK1
From
Bos taurus (Bovine) [TaxID: 9913] 
Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos.
Protein existence 1: Evidence at protein level;
References
[1]
 PROTEIN SEQUENCE.
DOI=10.1021/bi00306a012; PubMed=6089869 [NCBI, ExPASy, EBI, Israel, Japan]
Kuby S.A., Palmieri R.H., Frischat A., Fischer A.H., Wu L.H., Maland L., Manship M.;
"Studies on adenosine triphosphate transphosphorylases. Amino acid sequence of rabbit muscle ATP-AMP transphosphorylase.";
Biochemistry 23:2393-2399(1984).
[2]
 NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
DOI=10.1186/1471-2164-6-166; PubMed=16305752 [NCBI, ExPASy, EBI, Israel, Japan]
Harhay G.P., Sonstegard T.S., Keele J.W., Heaton M.P., Clawson M.L., Snelling W.M., Wiedmann R.T., Van Tassell C.P., Smith T.P.L.;
"Characterization of 954 bovine full-CDS cDNA sequences.";
BMC Genomics 6:166-166(2005).
[3]
 NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=Hereford;
TISSUE=Thymus;
NIH - Mammalian Gene Collection (MGC) project;
Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BT020951; AAX08968.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
BC114796; AAI14797.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR A00681; KIBOA.
RefSeq NP_001013600.1; -.
UniGene Bt.4224
3D structure databases
HSSP P00571; 3ADK. [HSSP ENTRY / SWISS-3DIMAGE / PDB]
SMR P00570; 1-193.
ModBase P00570.
Ontologies
GO
GO:0005515; Molecular function: protein binding (inferred from sequence or structural similarity from AgBase).
QuickGo view.
Family and domain databases
InterPro IPR000850; Adenylate_kin.
IPR006267; Adenylate_kin1.
Graphical view of domain structure.
PANTHER PTHR23359; Adenylate_kin; 1.
Pfam PF00406; ADK; 1.
Pfam graphical view of domain structure.
PRINTS PR00094; ADENYLTKNASE.
ProDom PD000657; Adenylate_kin; 1.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR01360; aden_kin_iso1; 1.
PROSITE PS00113; ADENYLATE_KINASE; 1.
BLOCKS P00570.
ProtoNet P00570.
Genome annotation databases
Ensembl ENSBTAG00000006305; Bos taurus. [Contig view]
GeneID 280715; -.
KEGG bta:280715; -.
Phylogenomic databases
HOVERGEN P00570; -.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Acetylation; ATP-binding; Cytoplasm; Direct protein sequencing; Kinase; Nucleotide-binding; Transferase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   194  194     Adenylate kinase isoenzyme 1. PRO_0000158909
NP_BIND   15    23  9     ATP (By similarity). 
MOD_RES   1     1        N-acetylmethionine. 
CONFLICT   8     8        T -> A (in Ref. 1; AA sequence). 
CONFLICT   85    85        D -> N (in Ref. 1; AA sequence). 
CONFLICT   98    98        E -> Q (in Ref. 1; AA sequence). 
CONFLICT   126   126        T -> Q (in Ref. 1; AA sequence). 
Sequence information
Length: 194 AA [This is the length of the unprocessed precursor] Molecular weight: 21664 Da [This is the MW of the unprocessed precursor] CRC64: 8F6EA93FBE3D3798 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MEEKLKKTKI IFVVGGPGSG KGTQCEKIVQ KYGYTHLSTG DLLRAEVSSG SARGKMLSEI 

        70         80         90        100        110        120 
MEKGQLVPLE TVLDMLRDAM VAKVDTSKGF LIDGYPREVQ QGEEFERRIA QPTLLLYVDA 

       130        140        150        160        170        180 
GPETMTKRLL KRGETSGRVD DNEETIKKRL ETYYKATEPV IAFYEKRGIV RKVNAEGSVD 

       190 
NVFSQVCTHL DALK
P00570 in FASTA format

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