PROTEIN SEQUENCE.
DOI=10.1021/bi00306a012; PubMed=6089869 [NCBI, ExPASy, EBI, Israel, Japan]
Kuby S.A., Palmieri R.H., Frischat A., Fischer A.H., Wu L.H., Maland L., Manship M.;
"Studies on adenosine triphosphate transphosphorylases. Amino acid sequence of rabbit muscle ATP-AMP transphosphorylase.";
Biochemistry 23:2393-2399(1984).

Comments

FUNCTION: This small ubiquitous enzyme is essential for maintenance and cell growth.
CATALYTIC ACTIVITY: ATP + AMP = 2 ADP.
SUBUNIT: Monomer.
SUBCELLULAR LOCATION: Cytoplasm.
SIMILARITY: Belongs to the adenylate kinase family.

Copyright

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Cross-references

Sequence databases
PIR	A00680; KIRBA.
3D structure databases
HSSP	P00571; 3ADK. [HSSP ENTRY / SWISS-3DIMAGE / PDB]
SMR	P00569; 1-193.
ModBase	P00569.
Family and domain databases
InterPro	IPR000850; Adenylate_kin. IPR006267; Adenylate_kin1. Graphical view of domain structure.
PANTHER	PTHR23359; Adenylate_kin; 1.
Pfam	PF00406; ADK; 1. Pfam graphical view of domain structure.
PRINTS	PR00094; ADENYLTKNASE.
ProDom	PD000657; Adenylate_kin; 1. [Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs	TIGR01360; aden_kin_iso1; 1.
PROSITE	PS00113; ADENYLATE_KINASE; 1.
BLOCKS	P00569.
ProtoNet	P00569.
Phylogenomic databases
HOVERGEN	P00569; -.
Other
UniRef	View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Acetylation; ATP-binding; Cytoplasm; Direct protein sequencing; Kinase; Nucleotide-binding; Transferase.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 194`	`194`	`Adenylate kinase isoenzyme 1.`	`PRO_0000158913`
`NP_BIND`	`15 23`	`9`	`ATP.`
`MOD_RES`	`1 1`		`N-acetylmethionine.`

Sequence information

Length: 194 AA [This is the length of the unprocessed precursor]

Molecular weight: 21638 Da [This is the MW of the unprocessed precursor]

CRC64: B579871616963214 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MEEKLKKAKI IFVVGGPGSG KGTQCEKIVH KYGYTHLSTG DLLRAEVSSG SARGKKLSEI 

        70         80         90        100        110        120 
MEKGQLVPLE TVLDMLRDAM VAKADTSKGF LIDGYPRQVQ QGEEFERRIA QPTLLLYVDA 

       130        140        150        160        170        180 
GPETMQKRLL KRGETSGRVD DNEETIKKRL ETYYKATEPV IAFYEKRGIV RKVNAEGSVD 

       190 
NVFSQVCTHL DALK

P00569 in FASTA format

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View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools