[1]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA].
DOI=10.1016/0378-1119(85)90174-X; PubMed=3928445 [NCBI, ExPASy, EBI, Israel, Japan]
Andrews J.,
Clore G.M.,
Davies R.W.,
Gronenborn A.M.,
Gronenborn B.,
Kalderon D.,
Papadopoulos P.C.,
Schaefer S.,
Sims P.F.G.,
Stancombe R.;
"Nucleotide sequence of the dihydrofolate reductase gene of methotrexate-resistant Lactobacillus casei.";
Gene 35:217-222(1985).
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[2]
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PROTEIN SEQUENCE OF 2-163.
PubMed=98527 [NCBI, ExPASy, EBI, Israel, Japan]
Freisheim J.H.,
Bitar K.G.,
Reddy A.V.,
Blankenship D.T.;
"Dihydrofolate reductase from amethopterin-resistant Lactobacillus casei. Sequences of the cyanogen bromide peptides and complete sequences of the enzyme.";
J. Biol. Chem. 253:6437-6444(1978).
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[3]
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PROTEIN SEQUENCE OF 2-52.
DOI=10.1016/0006-291X(77)91482-6; PubMed=405008 [NCBI, ExPASy, EBI, Israel, Japan]
Batley K.E.,
Morris H.R.;
"Dihydrofolate reductase from Lactobacillus casei: N-terminal sequence and comparison with the substrate binding region of other reductases.";
Biochem. Biophys. Res. Commun. 75:1010-1014(1977).
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[4]
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X-RAY CRYSTALLOGRAPHY (1.7 ANGSTROMS).
PubMed=6815179 [NCBI, ExPASy, EBI, Israel, Japan]
Filman D.J.,
Bolin J.T.,
Matthews D.A.,
Kraut J.;
"Crystal structures of Escherichia coli and Lactobacillus casei dihydrofolate reductase refined at 1.7-A resolution. II. Environment of bound NADPH and implications for catalysis.";
J. Biol. Chem. 257:13663-13672(1982).
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[5]
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STRUCTURE BY NMR.
DOI=10.1021/bi00239a035; PubMed=1905571 [NCBI, ExPASy, EBI, Israel, Japan]
Carr M.D.,
Birdsall B.,
Frenkiel T.A.,
Bauer C.J.,
Jimenez-Barbero J.,
Polshakov V.I.,
McCormick J.E.,
Roberts G.C.K.,
Feeney J.;
"Dihydrofolate reductase: sequential resonance assignments using 2D and 3D NMR and secondary structure determination in solution.";
Biochemistry 30:6330-6341(1991).
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[6]
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STRUCTURE BY NMR.
DOI=10.1021/bi00037a006; PubMed=7547901 [NCBI, ExPASy, EBI, Israel, Japan]
Morgan W.D.,
Birdsall B.,
Polshakov V.I.,
Sali D.,
Kompis I.,
Feeney J.;
"Solution structure of a brodimoprim analogue in its complex with Lactobacillus casei dihydrofolate reductase.";
Biochemistry 34:11690-11702(1995).
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[7]
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STRUCTURE BY NMR.
DOI=10.1006/jmbi.1997.1560; PubMed=9514736 [NCBI, ExPASy, EBI, Israel, Japan]
Gargaro A.R.,
Soteriou A.,
Frenkiel T.A.,
Bauer C.J.,
Birdsall B.,
Polshakov V.I.,
Barsukov I.L.,
Roberts G.C.K.,
Feeney J.;
"The solution structure of the complex of Lactobacillus casei dihydrofolate reductase with methotrexate.";
J. Mol. Biol. 277:119-134(1998).
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[8]
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STRUCTURE BY NMR.
PubMed=10091649 [NCBI, ExPASy, EBI, Israel, Japan]
Polshakov V.I.,
Birdsall B.,
Frenkiel T.A.,
Gargaro A.R.,
Feeney J.;
"Structure and dynamics in solution of the complex of Lactobacillus casei dihydrofolate reductase with the new lipophilic antifolate drug trimetrexate.";
Protein Sci. 8:467-481(1999).
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