[1]
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NUCLEOTIDE SEQUENCE [MRNA].
PubMed=3157987 [NCBI, ExPASy, EBI, Israel, Japan]
Edenberg H.J.,
Zhang K.,
Fong K.,
Bosron W.F.,
Li T.-K.;
"Cloning and sequencing of cDNA encoding the complete mouse liver alcohol dehydrogenase.";
Proc. Natl. Acad. Sci. U.S.A. 82:2262-2266(1985).
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[2]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA].
DOI=10.1016/0378-1119(87)90325-8; PubMed=2893758 [NCBI, ExPASy, EBI, Israel, Japan]
Ceci J.D.,
Zheng Y.W.,
Felder M.R.;
"Molecular analysis of mouse alcohol dehydrogenase: nucleotide sequence of the Adh-1 gene and genetic mapping of a related nucleotide sequence to chromosome 3.";
Gene 59:171-182(1987).
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[3]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA].
DOI=10.1016/0378-1119(87)90173-9; PubMed=3428612 [NCBI, ExPASy, EBI, Israel, Japan]
Zhang K.,
Bosron W.F.,
Edenberg H.J.;
"Structure of the mouse Adh-1 gene and identification of a deletion in a long alternating purine-pyrimidine sequence in the first intron of strains expressing low alcohol dehydrogenase activity.";
Gene 57:27-36(1987).
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[4]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=FVB/N;
TISSUE=Colon, and Kidney;
DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan]
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
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[5]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 8-51.
DOI=10.1093/nar/22.20.4132; PubMed=7937138 [NCBI, ExPASy, EBI, Israel, Japan]
Caubin J.,
Iglesias T.,
Bernal J.,
Munoz A.,
Marquez G.,
Barbero J.L.,
Zaballos A.;
"Isolation of genomic DNA fragments corresponding to genes modulated in vivo by a transcription factor.";
Nucleic Acids Res. 22:4132-4138(1994).
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[6]
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NUCLEOTIDE SEQUENCE [MRNA] OF 224-375.
STRAIN=SWR/J;
TISSUE=Liver;
DOI=10.1016/0378-1119(86)90101-0; PubMed=3011597 [NCBI, ExPASy, EBI, Israel, Japan]
Ceci J.D.,
Lawther R.,
Duester G.,
Hatfield G.W.,
Smith M.,
O'Malley M.P.,
Felder M.R.;
"Androgen induction of alcohol dehydrogenase in mouse kidney. Studies with a cDNA probe confirmed by nucleotide sequence analysis.";
Gene 41:217-224(1986).
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[7]
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TISSUE SPECIFICITY.
STRAIN=FVB/N;
DOI=10.1074/jbc.270.18.10868; PubMed=7738026 [NCBI, ExPASy, EBI, Israel, Japan]
Zgombic-Knight M.,
Ang H.L.,
Foglio M.H.,
Duester G.;
"Cloning of the mouse class IV alcohol dehydrogenase (retinol dehydrogenase) cDNA and tissue-specific expression patterns of the murine ADH gene family.";
J. Biol. Chem. 270:10868-10877(1995).
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- CATALYTIC ACTIVITY: An alcohol + NAD+ = an aldehyde or ketone + NADH.
- COFACTOR: Binds 2 zinc ions per subunit.
- SUBUNIT: Dimer of identical or non-identical chains of three types (A, B, C), which are coded by 3 separate genes at different loci.
- SUBCELLULAR LOCATION: Cytoplasm.
- TISSUE SPECIFICITY: Expressed at high levels in the liver, small intestine and eye, at moderate levels in kidney, ovary and uterus, and at low levels in the spinal cord, thymus, heart, stomach mucosa, skin and testis.
- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase family. Class-I subfamily.
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