ID   CYC_APIME               Reviewed;         108 AA.
AC   P00038; Q6J4P9;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   22-JUL-2008, entry version 74.
DE   RecName: Full=Cytochrome c;
GN   Name=cytC;
OS   Apis mellifera (Honeybee).
OC   Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Apoidea;
OC   Apidae; Apis.
OX   NCBI_TaxID=7460;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Corona M., Hughes K.A., Weaver D.B., Robinson G.E.;
RT   "Molecular mechanisms of honey bee queen longevity.";
RL   Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   PROTEIN SEQUENCE OF 2-108.
RX   MEDLINE=85261185; PubMed=2991212;
RA   Inoue S., Matsubara H., Yamanaka T.;
RT   "Complete amino acid sequence of cytochrome c from the honeybee, Apis
RT   mellifera, and evolutionary relationship of the honeybee to other
RT   insects on the basis of the amino acid sequence.";
RL   J. Biochem. 97:947-954(1985).
CC   -!- FUNCTION: Electron carrier protein. The oxidized form of the
CC       cytochrome c heme group can accept an electron from the heme group
CC       of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c
CC       then transfers this electron to the cytochrome oxidase complex,
CC       the final protein carrier in the mitochondrial electron-transport
CC       chain.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion matrix.
CC   -!- PTM: Binds 1 heme group per subunit.
CC   -!- SIMILARITY: Belongs to the cytochrome c family.
CC   -!- WEB RESOURCE: Name=Protein Spotlight; Note=Life shuttle - Issue 76
CC       of November 2006;
CC       URL="http://www.expasy.org/spotlight/back_issues/sptlt076.shtml";
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DR   EMBL; AY601642; AAT12410.1; -; mRNA.
DR   PIR; A00031; CCHB.
DR   RefSeq; XP_391823.1; -.
DR   UniGene; Ame.4918; -.
DR   HSSP; P00004; 2PCB.
DR   SMR; P00038; 6-107.
DR   Ensembl; ENSAPMG00000003281; Apis mellifera.
DR   GeneID; 408270; -.
DR   GO; GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
DR   InterPro; IPR009056; Cyt_c_monohaem.
DR   InterPro; IPR003088; Cyt_CI.
DR   InterPro; IPR002327; Cyt_CIAB.
DR   Gene3D; G3DSA:1.10.760.10; Cytochrome_c_R; 1.
DR   PANTHER; PTHR11961; Cyt_CIAB; 1.
DR   Pfam; PF00034; Cytochrom_C; 1.
DR   PRINTS; PR00604; CYTCHRMECIAB.
DR   ProDom; PD000375; Cyt_CIAB; 1.
DR   PROSITE; PS51007; CYTC; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Electron transport; Heme; Iron;
KW   Metal-binding; Mitochondrion; Respiratory chain; Transport.
FT   INIT_MET      1      1       Removed.
FT   CHAIN         2    108       Cytochrome c.
FT                                /FTId=PRO_0000108258.
FT   METAL        23     23       Iron (heme axial ligand).
FT   METAL        85     85       Iron (heme axial ligand).
FT   BINDING      19     19       Heme (covalent).
FT   BINDING      22     22       Heme (covalent).
SQ   SEQUENCE   108 AA;  11910 MW;  17C298A8B7092AB1 CRC64;
     MGIPAGDPEK GKKIFVQKCA QCHTIESGGK HKVGPNLYGV YGRKTGQAPG YSYTDANKGK
     GITWNKETLF EYLENPKKYI PGTKMVFAGL KKPQERADLI AYIEQASK
//