ID   RASF9_RAT               Reviewed;         435 AA.
AC   O88869;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   22-JUL-2008, entry version 35.
DE   RecName: Full=Ras association domain-containing protein 9;
DE   AltName: Full=Peptidylglycine alpha-amidating monooxygenase COOH-terminal interactor;
DE   AltName: Full=PAM COOH-terminal interactor protein 1;
DE            Short=P-CIP1;
GN   Name=Rassf9; Synonyms=Pamci, Pcip1;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;
OC   Muroidea; Muridae; Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, INTERACTION WITH PAM,
RP   SUBCELLULAR LOCATION, AND TISSUE SPECIFICITY.
RC   STRAIN=Sprague-Dawley;
RX   MEDLINE=99057917; PubMed=9837933; DOI=10.1074/jbc.273.50.33524;
RA   Chen L., Johnson R.C., Milgram S.L.;
RT   "P-CIP1, a novel protein that interacts with the cytosolic domain of
RT   peptidylglycine alpha-amidating monooxygenase, is associated with
RT   endosomes.";
RL   J. Biol. Chem. 273:33524-33532(1998).
CC   -!- FUNCTION: May play a role in regulating vesicuar trafficking in
CC       cells.
CC   -!- SUBUNIT: Interacts with PAM.
CC   -!- INTERACTION:
CC       P14925:Pam; NbExp=1; IntAct=EBI-1395057, EBI-1395008;
CC   -!- SUBCELLULAR LOCATION: Endosome. Note=Accumulates on perinuclear
CC       endosomes.
CC   -!- TISSUE SPECIFICITY: Testis, kidney, skeletal muscle, liver, lung,
CC       brain, heart, pituitary gland, adrenal gland and ovary.
CC   -!- SIMILARITY: Contains 1 Ras-associating domain.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; AF056208; AAD03249.1; -; mRNA.
DR   RefSeq; NP_075248.1; -.
DR   UniGene; Rn.30013; -.
DR   IntAct; O88869; -.
DR   Ensembl; ENSRNOG00000038574; Rattus norvegicus.
DR   GeneID; 65053; -.
DR   KEGG; rno:65053; -.
DR   RGD; 621329; Rassf9.
DR   HOVERGEN; O88869; -.
DR   ArrayExpress; O88869; -.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   InterPro; IPR000159; Ras-assoc.
DR   SMART; SM00314; RA; 1.
DR   PROSITE; PS50200; RA; 1.
PE   1: Evidence at protein level;
KW   Coiled coil; Endosome.
FT   CHAIN         1    435       Ras association domain-containing protein
FT                                9.
FT                                /FTId=PRO_0000299454.
FT   DOMAIN       25    119       Ras-associating.
FT   COILED      195    291       Potential.
SQ   SEQUENCE   435 AA;  49545 MW;  582AF0C52176E9B1 CRC64;
     MAPFGRNLLK TRHKNRSPTK DMDPEEKEIV VWVCQEEKIV CGLTKRTTSI DVIQALLEEH
     EATFGEKRFL LGKASDYCIV EKWRGSERAL PPLTRILKLW KAWGDEQPNM QFVLVKTDAF
     LPVPLWRTAE TKLVQNNEKP WELSPANYMK TLPPDKQKRI VRKTFRKLAK IRQDTGSHDR
     DNMECLVHLI ISQDHTIHQQ VQRMKELDME IEKCEAKIHL DRIGNDGADY VQEAYLMPRS
     SEEEQKLDFQ SEDNQTLEDL NDGEGVSQLE EQLQYYRALI DKLSAEIERE VKGAGTDGSE
     DMEGAAACEL ENSDLESVKC DLEKSMKAGL KIHSHLSGIQ REIKYSDSLL QMKAREYELL
     AKEFSSLHIS SKDGCQGKEN RGKEAEASSS NGEIPPLTQR VFNTYTNDTD SDTGISSNHS
     QDSETTLGDV LLLAT
//