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UniProtKB/Swiss-Prot entry O86564


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name SDHL_STRCO
Primary accession number O86564
Secondary accession numbers None
Integrated into Swiss-Prot on July 15, 1999
Sequence was last modified on November 1, 1998 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 49)
Name and origin of the protein
Protein name L-serine dehydratase
Synonyms SDH
EC 4.3.1.17
L-serine deaminase
L-SD
Gene name
Name: sdaA
OrderedLocusNames: SCO5469
ORFNames: SC2A11.03c
From
Streptomyces coelicolor [TaxID: 1902] [HAMAP proteome]
Taxonomy Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; Streptomycineae; Streptomycetaceae; Streptomyces.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC BAA-471 / A3(2) / M145;
DOI=10.1038/417141a; PubMed=12000953 [NCBI, ExPASy, EBI, Israel, Japan]
Bentley S.D., Chater K.F., Cerdeno-Tarraga A.-M., Challis G.L., Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D., Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A., Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.-H., Kieser T., Larke L., Murphy L.D., Oliver K., O'Neil S., Rabbinowitsch E., Rajandream M.A., Rutherford K.M., Rutter S., Seeger K., Saunders D., Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A., Woodward J.R., Barrell B.G., Parkhill J., Hopwood D.A.;
"Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).";
Nature 417:141-147(2002).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AL939123; CAA20172.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR T34749; T34749.
RefSeq NP_629605.1; -.
3D structure databases
ModBase O86564.
Enzyme and pathway databases
BioCyc SCOE100226:SCO5469-MON; -.
Ontologies
GO
GO:0051539; Molecular function: 4 iron, 4 sulfur cluster binding (inferred from electronic annotation from UniProtKB-KW).
GO:0005506; Molecular function: iron ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0003941; Molecular function: L-serine ammonia-lyase activity (inferred from electronic annotation from InterPro).
GO:0006094; Biological process: gluconeogenesis (inferred from electronic annotation from InterPro).
QuickGo view.
Family and domain databases
InterPro IPR004644; Fe-S_L-Ser_mono.
IPR005130; Ser_deHydtase_asu.
IPR005131; Ser_deHydtase_bsu.
Graphical view of domain structure.
Pfam PF03313; SDH_alpha; 1.
PF03315; SDH_beta; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00720; sda_mono; 1.
Genome annotation databases
GeneID 1100909; -.
GenomeReviews AL645882_GR; SCO5469.
KEGG sco:SCO5469; -.
NMPDR fig|100226.1.peg.5421; -.
Phylogenomic databases
HOGENOM O86564; -.
Genome annotation databases
CMR O86564; SCO5469.
Other
ProtoNet O86564.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
4Fe-4S; Complete proteome; Gluconeogenesis; Iron; Iron-sulfur; Lyase; Metal-binding.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   455  455     L-serine dehydratase. PRO_0000171911
Sequence information
Length: 455 AA [This is the length of the unprocessed precursor] Molecular weight: 48601 Da [This is the MW of the unprocessed precursor] CRC64: 3FE9DD03EEC4A526 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MAISVFDLFS IGIGPSSSHT VGPMRAARMF ARRLRNEELL DSVASVRVEL YGSLGATGHG 

        70         80         90        100        110        120 
HGTPKAVLLG LEGDSPRTVD VESADDRVET IKSSGRISLL GDHEIAFAYD DDMVLHRRKA 

       130        140        150        160        170        180 
LPYHANGMTL WAYDAEGAEV LTKTYYSVGG GFVVDEDAVG ADRIVLDDTV LKYPFRTGDE 

       190        200        210        220        230        240 
LLRLARETGL SISALMLENE RAWRDEDEIR EGLLEIWRVM RACVDRGMTR EGILPGGLKV 

       250        260        270        280        290        300 
RRRAANTARK LRSEGDPQAL AMEWITLYAM AVNEENAAGG RVVTAPTNGA AGIIPAVLHY 

       310        320        330        340        350        360 
YMNFVPGADE DGVVRFLLAA GAIGMLFKEN ASISGAEVGC QGEVGSACSM AAGALAEVLG 

       370        380        390        400        410        420 
GSPEQVENAA EIGMEHNLGL TCDPVGGLVQ IPCIERNGMA AVKAVTAARM AMRGDGSHKV 

       430        440        450 
SLDKVIKTMK ETGADMSVKY KETARGGLAV NIIEC 

O86564 in FASTA format

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