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UniProtKB/Swiss-Prot entry O83351


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name 6PGD_TREPA
Primary accession number O83351
Secondary accession numbers None
Integrated into Swiss-Prot on December 15, 1998
Sequence was last modified on November 1, 1998 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 53)
Name and origin of the protein
Protein name 6-phosphogluconate dehydrogenase, decarboxylating
Synonym EC 1.1.1.44
Gene name
Name: gnd
OrderedLocusNames: TP_0331
From
Treponema pallidum [TaxID: 160] [HAMAP proteome]
Taxonomy Bacteria; Spirochaetes; Spirochaetales; Spirochaetaceae; Treponema.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Nichols;
DOI=10.1126/science.281.5375.375; PubMed=9665876 [NCBI, ExPASy, EBI, Israel, Japan]
Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G., Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A., Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D., Khalak H.G., Richardson D.L., Howell J.K., Chidambaram M., Utterback T.R., McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A., Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O., Venter J.C.;
"Complete genome sequence of Treponema pallidum, the syphilis spirochete.";
Science 281:375-388(1998).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE000520; AAC65319.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR A71337; A71337.
RefSeq NP_218771.1; -.
3D structure databases
HSSP P00349; 2PGD. [HSSP ENTRY / PDB]
ModBase O83351.
Enzyme and pathway databases
BioCyc TPAL243276:TP_0331-MON; -.
Family and domain databases
InterPro IPR006183; 6-phosphogluconate_DHase.
IPR006114; 6PGDH_C.
IPR006113; 6PGDH_decarbox.
IPR006115; 6PGDH_NAD-bd.
IPR006184; 6PGdom_BS.
IPR013328; DHase_multihelical.
IPR012284; Fibritin/6PGD_C-extension.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:1.20.5.320; Fibritin/6PGD_C-extension; 1.
G3DSA:3.40.50.720; NAD(P)-bd; 1.
G3DSA:1.10.1040.10; Opine_DH; 1.
Pfam PF00393; 6PGD; 1.
PF03446; NAD_binding_2; 1.
Pfam graphical view of domain structure.
PRINTS PR00076; 6PGDHDRGNASE.
TIGRFAMs TIGR00873; gnd; 1.
PROSITE PS00461; 6PGD; 1.
BLOCKS O83351.
Genome annotation databases
GeneID 2611604; -.
GenomeReviews AE000520_GR; TP_0331.
KEGG tpa:TP0331; -.
NMPDR fig|243276.1.peg.330; -.
TIGR TP_0331; -.
Phylogenomic databases
HOGENOM O83351; -.
Other
ProtoNet O83351.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Gluconate utilization; NADP; Oxidoreductase; Pentose shunt.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   488  488     6-phosphogluconate dehydrogenase, decarboxylating. PRO_0000090062
Sequence information
Length: 488 AA [This is the length of the unprocessed precursor] Molecular weight: 52767 Da [This is the MW of the unprocessed precursor] CRC64: FB69CCCA98DEE6B5 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MGADIGFIGL AVMGENLVLN IERNGFSVAV FNRTTTVVDR FLAGRAHGKR ITGAHSIAEL 

        70         80         90        100        110        120 
VSLLARPRKI MLMVKAGSAV DAVIDQILPL LEKGDLVIDG GNSHYQDTIR RMHALEAAGI 

       130        140        150        160        170        180 
HFIGTGVSGG EEGALRGPSL MPGGSAQAWP LVSPIFCAIA AKADDGTPCC DWVGSDGAGH 

       190        200        210        220        230        240 
YVKMIHNGIE YGDMQIIAEG YWFMKHALGM SYEHMHHTFT RWNTGRLHSY LIEITAAILA 

       250        260        270        280        290        300 
HQDTDGTPLL EKILDAAGQK GTGRWTCVAA LEEGSPLTLI TESVMARSLS AQKQARCKAH 

       310        320        330        340        350        360 
RVFGSPVKVS KAETLSAQQR EELVSALEDA LYCAKIVSYA QGFELLSHTA KRRGWTLDFS 

       370        380        390        400        410        420 
RIASLWRGGC IIRSGFLSKI SAAFAQQHDL ENLVLAPFFA EELKRACPGW RTIVAESVRQ 

       430        440        450        460        470        480 
ALPVPALSAA LAWFDGFTGA ALPANLLQAQ RDYFGAHTYE RTDAPRGEFF HTNWTGTGGD 


TIAGTYSI 

O83351 in FASTA format

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