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UniProtKB/Swiss-Prot entry O69077


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name AK_PSEAE
Primary accession number O69077
Secondary accession number Q9I552
Integrated into Swiss-Prot on January 11, 2001
Sequence was last modified on January 11, 2001 (Sequence version 2)
Annotations were last modified on    July 22, 2008 (Entry version 51)
Name and origin of the protein
Protein name Aspartokinase
Synonyms EC 2.7.2.4
Aspartate kinase
Gene name
Name: lysC
OrderedLocusNames: PA0904
From
Pseudomonas aeruginosa [TaxID: 287] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228;
DOI=10.1038/35023079; PubMed=10984043 [NCBI, ExPASy, EBI, Israel, Japan]
Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P., Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M., Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y., Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M., Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J., Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
"Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen.";
Nature 406:959-964(2000).
[2]
NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 198-412.
STRAIN=ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228;
Hindle Z., Throup J.P., Francis K.P., Bycroft B.W., Williams P., Stewart G.S.A.B.;
Submitted (APR-1998) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE004091; AAG04293.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AF061757; AAC16241.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR C83531; C83531.
RefSeq NP_249595.1; -.
3D structure databases
ModBase O69077.
Enzyme and pathway databases
BioCyc PAER208964:PA0904-MON; -.
Organism-specific databases
PseudoCAP PA0904; -.
Family and domain databases
InterPro IPR002912; ACT_bd.
IPR001048; Asp/Glu/Uridylate_kinase.
IPR005260; Asp_kin_monofn.
IPR001341; Asp_kin_reg.
Graphical view of domain structure.
Gene3D G3DSA:3.40.1160.10; Aa_kinase; 1.
Pfam PF00696; AA_kinase; 1.
PF01842; ACT; 2.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00656; asp_kin_monofn; 1.
TIGR00657; asp_kinases; 1.
PROSITE PS00324; ASPARTOKINASE; 1.
BLOCKS O69077.
Genome annotation databases
GeneID 878315; -.
GenomeReviews AE004091_GR; PA0904.
KEGG pae:PA0904; -.
Phylogenomic databases
HOGENOM O69077; -.
Genome annotation databases
CMR O69077; PA0904.
Other
ProtoNet O69077.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Complete proteome; Diaminopimelate biosynthesis; Kinase; Lysine biosynthesis; Repeat; Transferase.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   412  412     Aspartokinase. PRO_0000066679
DOMAIN   265   336  72     ACT 1. 
DOMAIN   345   410  66     ACT 2. 
Sequence information
Length: 412 AA [This is the length of the unprocessed precursor] Molecular weight: 44389 Da [This is the MW of the unprocessed precursor] CRC64: A06ACAA5E914F337 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MALIVQKFGG TSVGTVERIE QVAEKVKKFR EAGDDVVVVV SAMSGETNRL IGLANQIMEQ 

        70         80         90        100        110        120 
PVPRELDVMV STGEQVTIAL LSMALIKRGV PAVSYTGNQV RILTDSAHTK ARILHIDDTH 

       130        140        150        160        170        180 
IRADLKAGRV VVVAGFQGVD GNGNITTLGR GGSDTTGVAL AAALKADECQ IYTDVDGVYT 

       190        200        210        220        230        240 
TDPRVVPQAR RLDKITFEEM LEMASLGSKV LQIRAVEFAG KYNVPLRVLH SFQEGPGTLI 

       250        260        270        280        290        300 
TIDDEEESME QPIISGIAFN RDEAKLTIRG VPDTPGVAFK ILGPISAANV EVDMIVQNVA 

       310        320        330        340        350        360 
HDNTTDFTFT VHRNDYLNAL EILKQTAANI GAREAIGDTN IAKVSIVGVG MRSHAGVASR 

       370        380        390        400        410 
MFEALAKESI NIQMISTSEI KVSVVIEEKY LELAVRALHT AFELDAPARQ GE 

O69077 in FASTA format

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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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