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UniProtKB/Swiss-Prot entry O58050

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name PPCK_PYRHO
Primary accession number O58050
Secondary accession numbers None
Integrated into Swiss-Prot on September 26, 2001
Sequence was last modified on August 1, 1998 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 52)
Name and origin of the protein
Protein name Phosphoenolpyruvate carboxykinase [GTP]
Synonyms PEP carboxykinase
EC 4.1.1.32
Phosphoenolpyruvate carboxylase
PEPCK
Gene name
Name: pckG
OrderedLocusNames: PH0312
From
Pyrococcus horikoshii [TaxID: 53953] [HAMAP proteome]
Taxonomy Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae; Pyrococcus.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=OT3;
DOI=10.1093/dnares/5.2.55; PubMed=9679194 [NCBI, ExPASy, EBI, Israel, Japan]
Kawarabayasi Y., Sawada M., Horikawa H., Haikawa Y., Hino Y., Yamamoto S., Sekine M., Baba S., Kosugi H., Hosoyama A., Nagai Y., Sakai M., Ogura K., Otsuka R., Nakazawa H., Takamiya M., Ohfuku Y., Funahashi T., Tanaka T., Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K., Yoshizawa T., Nakamura Y., Robb F.T., Horikoshi K., Masuchi Y., Shizuya H., Kikuchi H.;
"Complete sequence and gene organization of the genome of a hyper-thermophilic archaebacterium, Pyrococcus horikoshii OT3.";
DNA Res. 5:55-76(1998).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BA000001; BAA29385.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR B71457; B71457.
RefSeq NP_142297.1; -.
3D structure databases
HSSP P35558; 1KHB. [HSSP ENTRY / PDB]
ModBase O58050.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0005525; Molecular function: GTP binding (inferred from electronic annotation from HAMAP).
GO:0004613; Molecular function: phosphoenolpyruvate carboxykinase (GTP) activity (inferred from electronic annotation from HAMAP).
GO:0006094; Biological process: gluconeogenesis (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00452; -; 1.
PBIL [Tree]
InterPro IPR013035; PEP_carboxykinase_C.
IPR008209; PEP_carboxykinase_GTP.
IPR008210; PEP_carboxykinase_N.
Graphical view of domain structure.
Gene3D G3DSA:3.90.228.20; PEP_carboxykinase_C; 1.
G3DSA:3.40.449.10; PEP_carboxykinase_N; 1.
PANTHER PTHR11561; PEP_carboxykin; 1.
Pfam PF00821; PEPCK; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF001348; PEP_carboxykinase_GTP; 1.
ProDom PD004738; PEPCK_N; 1.
[Domain structure / List of seq. sharing at least 1 domain]
PROSITE PS00505; PEPCK_GTP; 1.
Genome annotation databases
GeneID 1444192; -.
GenomeReviews BA000001_GR; PH0312.
KEGG pho:PH0312; -.
NMPDR fig|70601.1.peg.292; -.
Phylogenomic databases
HOGENOM O58050; -.
Genome annotation databases
CMR O58050; PH0312.
Other
ProtoNet O58050.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; Decarboxylase; Gluconeogenesis; GTP-binding; Lyase; Nucleotide-binding.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   621  621     Phosphoenolpyruvate carboxykinase [GTP]. PRO_0000103619
NP_BIND   218   225  8     GTP (Potential). 
ACT_SITE   269   269        By similarity. 
Sequence information
Length: 621 AA [This is the length of the unprocessed precursor] Molecular weight: 72202 Da [This is the MW of the unprocessed precursor] CRC64: 738232FF30F20F01 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MEKLRELLPK DQYEKIAAIN NPYLHEFLAE WIEWLEPSKV FVCTDSPEDE EYVRWKALYY 

        70         80         90        100        110        120 
GEEKMLEIPK HTVHYDNYYD QARDKTNTKL LVPKGVELPF LNTMNREEGL KEIREIMKGI 

       130        140        150        160        170        180 
MRGKELFICF FVLGPTNSIF TIPAVQLTDS AYVAHSEFLL YRKGYEEFKR LGPTKNFFKF 

       190        200        210        220        230        240 
VHSAGELDER KTSKNLDKRR IYIDLLDETV YSANTQYGGN TIGLKKLAFR LTIQRAVKEG 

       250        260        270        280        290        300 
WLSEHMFLMR VNGPNGRKTY FTGAYPSMCG KTSTAMIPWE NIVGDDLVFI KNVDGIARAV 

       310        320        330        340        350        360 
NVEIGVFGII EGVNQKDDPI IWKVLHSPVE IIFSNVLVKD GKPYWNGMGI EIPDEGENHS 

       370        380        390        400        410        420 
GKWWRGKRDA EGKEIPPSHK NARFTVRLEA FPNLDREALN NPCGVEVGGM IFGGRDPDTW 

       430        440        450        460        470        480 
PPVREAFDWE HGVITMGASL ESETTAATLG KEGVRAFNPM SILDFLSVHI GDYIRNYLEF 

       490        500        510        520        530        540 
GRKLKKTPKI FAVNYFLREN GRWLNEKLDK AVWLKWMELR VHNDVDAIET PIGYIPRYED 

       550        560        570        580        590        600 
LKVLFKQVLN KDYSREDYEK QFKIRVPELL AKIERIWKIY EPIDNIPEEL FKQLKDERER 

       610        620 
LLKAKAEFGD YISPFTLEKR I
O58050 in FASTA format

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