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[1]
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NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=OT3;
DOI=10.1093/dnares/5.2.55; PubMed=9679194 [NCBI, ExPASy, EBI, Israel, Japan]
Kawarabayasi Y.,
Sawada M.,
Horikawa H.,
Haikawa Y.,
Hino Y.,
Yamamoto S.,
Sekine M.,
Baba S.,
Kosugi H.,
Hosoyama A.,
Nagai Y.,
Sakai M.,
Ogura K.,
Otsuka R.,
Nakazawa H.,
Takamiya M.,
Ohfuku Y.,
Funahashi T.,
Tanaka T., ![]()
Kudoh Y.,
Yamazaki J.,
Kushida N.,
Oguchi A.,
Aoki K.,
Yoshizawa T.,
Nakamura Y.,
Robb F.T.,
Horikoshi K.,
Masuchi Y.,
Shizuya H.,
Kikuchi H.;
"Complete sequence and gene organization of the genome of a hyper-thermophilic archaebacterium, Pyrococcus horikoshii OT3.";
DNA Res. 5:55-76(1998).
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- FUNCTION: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein (By similarity).
- CATALYTIC ACTIVITY: Glycine + H-protein-lipoyllysine = H-protein-S-aminomethyldihydrolipoyllysine + CO2.
- SUBUNIT: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is an heterodimer of two subunits (By similarity).
- SIMILARITY: Belongs to the gcvP family. N-terminal subunit subfamily.
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Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms.
Distributed under the Creative Commons Attribution-NoDerivs License.
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| Length: 449 AA [This is the length of the unprocessed precursor] |
Molecular weight: 50357 Da [This is the MW of the unprocessed precursor] |
CRC64: C7DE610E8A0254DC [This is a checksum on the sequence] |
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10 20 30 40 50 60
MGNHYIPNSA HKEEMLKEIG LSSIEELFAD IPEKFIKEEL NLPEGKSEYE VFLEMNEILE
70 80 90 100 110 120
KNKTVLEMPT FLGAGTYFHY IPAHVKHLIE RSEFLTSYTP YQPEISQGML QALFEYQSLI
130 140 150 160 170 180
AELVGLPVVN SSMYDWGTAM AEAALMTVRL HKGKRKKFVV PKHTHPERLQ VLRTYTRGPE
190 200 210 220 230 240
VEIVTVNWNE RGQVDVEDLK EKVKDAAGVY IEIPNFFGLL EEEIREVGEI AHEAGAYFVV
250 260 270 280 290 300
GVDPTILGIV EAPGELGADI VVGEASYFGN PMNFGGPRAG IFAVKNDMKL IRQMPGRIIG
310 320 330 340 350 360
MTKDAEGKRA FVMTLQTREQ HIRRAKATSN ICSNEALVAV AAAIHIASLG PKGIRELGEV
370 380 390 400 410 420
ILKNTAYLKK RLSEVAEIPF DGVNFKDVLV RFDKPYREIH EELLKRNIHG GYYVGSHFPE
430 440
LGEAALFAAT ETTRKEWVDA LISALKEVI
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O57708 in FASTA format |
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