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UniProtKB/Swiss-Prot entry O55044

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name G6PD_CRIGR
Primary accession number O55044
Secondary accession numbers None
Integrated into Swiss-Prot on April 12, 2005
Sequence was last modified on January 23, 2007 (Sequence version 3)
Annotations were last modified on    September 2, 2008 (Entry version 58)
Name and origin of the protein
Protein name Glucose-6-phosphate 1-dehydrogenase
Synonyms G6PD
EC 1.1.1.49
Gene name
Name: G6PD
From
Cricetulus griseus (Chinese hamster) [TaxID: 10029] 
Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Cricetidae; Cricetinae; Cricetulus.
Protein existence 2: Evidence at transcript level;
References
[1]
 NUCLEOTIDE SEQUENCE [MRNA].
TISSUE=Ovary;
Perez M.L., Stamato T.D.;
"cDNA sequence of Chinese hamster glucose-6-phosphate Dehydrogenase.";
Submitted (JAN-1998) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AF044676; AAC00204.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
3D structure databases
HSSP P11413; 1QKI. [HSSP ENTRY / PDB]
SMR O55044; 27-514, 28-515.
ModBase O55044.
Family and domain databases
InterPro IPR001282; Glc-6-P_DHase.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
PANTHER PTHR23429; G6PDH; 1.
Pfam PF02781; G6PD_C; 1.
PF00479; G6PD_N; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000110; G6PD; 1.
PRINTS PR00079; G6PDHDRGNASE.
ProDom PD001129; G6PD; 1.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR00871; zwf; 1.
PROSITE PS00069; G6P_DEHYDROGENASE; 1.
BLOCKS O55044.
Phylogenomic databases
HOVERGEN O55044; -.
Other
ProtoNet O55044.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Acetylation; Carbohydrate metabolism; Glucose metabolism; NADP; Oxidoreductase; Phosphoprotein.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
INIT_MET   1     1        Removed (By similarity). 
CHAIN   2   515  514     Glucose-6-phosphate 1-dehydrogenase. PRO_0000068081
ACT_SITE   263   263        Proton acceptor (By similarity). 
BINDING   40    40        NADP (By similarity). 
BINDING   72    72        NADP (By similarity). 
BINDING   201   201        Substrate (By similarity). 
BINDING   205   205        Substrate (By similarity). 
MOD_RES   2     2        N-acetylalanine (By similarity). 
MOD_RES   401   401        Phosphotyrosine (By similarity). 
MOD_RES   503   503        Phosphotyrosine (By similarity). 
MOD_RES   507   507        Phosphotyrosine (By similarity). 
Sequence information
Length: 515 AA [This is the length of the unprocessed precursor] Molecular weight: 59326 Da [This is the MW of the unprocessed precursor] CRC64: 892DD70C86C7438C [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MAEQVALSRT QVCGILREEL YQGDAFHQAD THIFIIMGAS GDLAKKKIYP TIWWLFRDGL 

        70         80         90        100        110        120 
LPEDTFIVGY ARSRLTVDDI RKQSEPFFKA TPEERPKLEE FFARNSYVAG QYDDPASYKH 

       130        140        150        160        170        180 
LNSHMNALHQ GMQANRLFYL ALPPTVYEAV TKNIQETCMS QTGWNRIIVE KPFGRDLQSS 

       190        200        210        220        230        240 
NQLSNHISSL FREDQIYRID HYLGKEMVQN LMVLRFANRI FGPIWNRDNI ACVILTFKEP 

       250        260        270        280        290        300 
FGTEGRGGYF DEFGIIRDVM QNHLLQMLCL VAMEKPASTD SDDVRDEKVK VLKCISEVET 

       310        320        330        340        350        360 
SNVVLGQYVG NPNGEGEATN GYLDDPTVPR GSTTATFAAA VLYVENERWD GVPFILRCGK 

       370        380        390        400        410        420 
ALNERKAEVR LQFRDVAGDI FHQQCKRNEL VIRVQPNEAV YTKMMTKKPG MFFNPEESEL 

       430        440        450        460        470        480 
DLTYGNRYKN VKLPDAYERL ILDVFCGSQM HFVRSDELRE AWRIFTPLLH KIDQEKPQPI 

       490        500        510 
PYVYGSRGPT EADELMKRVG FQYEGTYKWV NPHKL
O55044 in FASTA format

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