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[1]
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NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 35210 / B31 / CIP 102532 / DSM 4680;
DOI=10.1038/37551; PubMed=9403685 [NCBI, ExPASy, EBI, Israel, Japan]
Fraser C.M.,
Casjens S.,
Huang W.M.,
Sutton G.G.,
Clayton R.A.,
Lathigra R.,
White O.,
Ketchum K.A.,
Dodson R.J.,
Hickey E.K.,
Gwinn M.L.,
Dougherty B.A.,
Tomb J.-F.,
Fleischmann R.D.,
Richardson D.L.,
Peterson J.D.,
Kerlavage A.R.,
Quackenbush J.,
Salzberg S.L., ![]()
Hanson M.,
van Vugt R.,
Palmer N.,
Adams M.D.,
Gocayne J.D.,
Weidman J.F.,
Utterback T.R.,
Watthey L.,
McDonald L.A.,
Artiach P.,
Bowman C.,
Garland S.A.,
Fujii C.,
Cotton M.D.,
Horst K.,
Roberts K.M.,
Hatch B.,
Smith H.O.,
Venter J.C.;
"Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi.";
Nature 390:580-586(1997).
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- FUNCTION: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity).
- CATALYTIC ACTIVITY: Hydrolysis of proteins to small peptides in the presence of ATP and magnesium. Alpha-casein is the usual test substrate. In the absence of ATP, only oligopeptides shorter than five residues are hydrolyzed (such as succinyl-Leu-Tyr-|-NHMec; and Leu-Tyr-Leu-|-Tyr-Trp, in which cleavage of the -Tyr-|-Leu- and -Tyr-|-Trp bonds also occurs).
- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
- SIMILARITY: Belongs to the peptidase S14 family [view classification].
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Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms.
Distributed under the Creative Commons Attribution-NoDerivs License.
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| Length: 197 AA [This is the length of the unprocessed precursor] |
Molecular weight: 22064 Da [This is the MW of the unprocessed precursor] |
CRC64: 5044A9D2053E648A [This is a checksum on the sequence] |
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10 20 30 40 50 60
MEFMHNLIPT VIENTGNYER VFDIYSRLLR ERIIFLSGEI NDPKADTVIA QLLFLESEDS
70 80 90 100 110 120
SKDIYLYLNS PGGSITAGLA IYDTMQYIKP DVRTICIGQA ASMGAFLLAG GAKGKRESLT
130 140 150 160 170 180
YSRIMIHQPW GGISGQASDI NIQANEILRL KKLIIDIMSN QIGVDKEKLA LDMERDYFMT
190
SSDALKYGLI DSILVRE
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O51556 in FASTA format |
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