[1]
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NUCLEOTIDE SEQUENCE [MRNA], AND TISSUE SPECIFICITY.
TISSUE=Rhabdomyosarcoma;
DOI=10.1006/geno.1997.5122; PubMed=9479491 [NCBI, ExPASy, EBI, Israel, Japan]
Anderson M.J.,
Viars C.S.,
Czekay S.,
Cavenee W.K.,
Arden K.C.;
"Cloning and characterization of three human forkhead genes that comprise an FKHR-like gene subfamily.";
Genomics 47:187-199(1998).
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[2]
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NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1038/nature02055; PubMed=14574404 [NCBI, ExPASy, EBI, Israel, Japan]
Mungall A.J.,
Palmer S.A.,
Sims S.K.,
Edwards C.A.,
Ashurst J.L.,
Wilming L.,
Jones M.C.,
Horton R.,
Hunt S.E.,
Scott C.E.,
Gilbert J.G.R.,
Clamp M.E.,
Bethel G.,
Milne S.,
Ainscough R.,
Almeida J.P.,
Ambrose K.D.,
Andrews T.D.,
Ashwell R.I.S., ![]()
Babbage A.K.,
Bagguley C.L.,
Bailey J.,
Banerjee R.,
Barker D.J.,
Barlow K.F.,
Bates K.,
Beare D.M.,
Beasley H.,
Beasley O.,
Bird C.P.,
Blakey S.E.,
Bray-Allen S.,
Brook J.,
Brown A.J.,
Brown J.Y.,
Burford D.C.,
Burrill W.,
Burton J.,
Carder C.,
Carter N.P.,
Chapman J.C.,
Clark S.Y.,
Clark G.,
Clee C.M.,
Clegg S.,
Cobley V.,
Collier R.E.,
Collins J.E.,
Colman L.K.,
Corby N.R.,
Coville G.J.,
Culley K.M.,
Dhami P.,
Davies J.,
Dunn M.,
Earthrowl M.E.,
Ellington A.E.,
Evans K.A.,
Faulkner L.,
Francis M.D.,
Frankish A.,
Frankland J.,
French L.,
Garner P.,
Garnett J.,
Ghori M.J.,
Gilby L.M.,
Gillson C.J.,
Glithero R.J.,
Grafham D.V.,
Grant M.,
Gribble S.,
Griffiths C.,
Griffiths M.N.D.,
Hall R.,
Halls K.S.,
Hammond S.,
Harley J.L.,
Hart E.A.,
Heath P.D.,
Heathcott R.,
Holmes S.J.,
Howden P.J.,
Howe K.L.,
Howell G.R.,
Huckle E.,
Humphray S.J.,
Humphries M.D.,
Hunt A.R.,
Johnson C.M.,
Joy A.A.,
Kay M.,
Keenan S.J.,
Kimberley A.M.,
King A.,
Laird G.K.,
Langford C.,
Lawlor S.,
Leongamornlert D.A.,
Leversha M.,
Lloyd C.R.,
Lloyd D.M.,
Loveland J.E.,
Lovell J.,
Martin S.,
Mashreghi-Mohammadi M.,
Maslen G.L.,
Matthews L.,
McCann O.T.,
McLaren S.J.,
McLay K.,
McMurray A.,
Moore M.J.F.,
Mullikin J.C.,
Niblett D.,
Nickerson T.,
Novik K.L.,
Oliver K.,
Overton-Larty E.K.,
Parker A.,
Patel R.,
Pearce A.V.,
Peck A.I.,
Phillimore B.J.C.T.,
Phillips S.,
Plumb R.W.,
Porter K.M.,
Ramsey Y.,
Ranby S.A.,
Rice C.M.,
Ross M.T.,
Searle S.M.,
Sehra H.K.,
Sheridan E.,
Skuce C.D.,
Smith S.,
Smith M.,
Spraggon L.,
Squares S.L.,
Steward C.A.,
Sycamore N.,
Tamlyn-Hall G.,
Tester J.,
Theaker A.J.,
Thomas D.W.,
Thorpe A.,
Tracey A.,
Tromans A.,
Tubby B.,
Wall M.,
Wallis J.M.,
West A.P.,
White S.S.,
Whitehead S.L.,
Whittaker H.,
Wild A.,
Willey D.J.,
Wilmer T.E.,
Wood J.M.,
Wray P.W.,
Wyatt J.C.,
Young L.,
Younger R.M.,
Bentley D.R.,
Coulson A.,
Durbin R.M.,
Hubbard T.,
Sulston J.E.,
Dunham I.,
Rogers J.,
Beck S.;
"The DNA sequence and analysis of human chromosome 6.";
Nature 425:805-811(2003).
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[3]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
TISSUE=Muscle, and Placenta;
DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan]
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
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[4]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] OF 1-383, AND INVOLVEMENT IN SECONDARY ACUTE LEUKEMIAS.
PubMed=9345057 [NCBI, ExPASy, EBI, Israel, Japan]
Hillion J.,
Le Coniat M.,
Jonveaux P.,
Berger R.,
Bernard O.A.;
"AF6q21, a novel partner of the MLL gene in t(6;11)(q21;q23), defines a forkhead transcriptional factor subfamily.";
Blood 90:3714-3719(1997).
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[5]
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FUNCTION, SUBCELLULAR LOCATION, PHOSPHORYLATION AT THR-32; SER-253 AND SER-315, AND MUTAGENESIS OF THR-32; SER-253 AND SER-315.
DOI=10.1016/S0092-8674(00)80595-4; PubMed=10102273 [NCBI, ExPASy, EBI, Israel, Japan]
Brunet A.,
Bonni A.,
Zigmond M.J.,
Lin M.Z.,
Juo P.,
Hu L.S.,
Anderson M.J.,
Arden K.C.,
Blenis J.,
Greenberg M.E.;
"Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor.";
Cell 96:857-868(1999).
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[6]
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PHOSPHORYLATION AT SER-315.
DOI=10.1128/MCB.21.3.952-965.2001; PubMed=11154281 [NCBI, ExPASy, EBI, Israel, Japan]
Brunet A.,
Park J.,
Tran H.,
Hu L.S.,
Hemmings B.A.,
Greenberg M.E.;
"Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a).";
Mol. Cell. Biol. 21:952-965(2001).
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[7]
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FUNCTION, PHOSPHORYLATION AT SER-209, INTERACTION WITH STK4 AND YWHAB, SUBCELLULAR LOCATION, AND MUTAGENESIS OF SER-209.
DOI=10.1016/j.cell.2006.03.046; PubMed=16751106 [NCBI, ExPASy, EBI, Israel, Japan]
Lehtinen M.K.,
Yuan Z.,
Boag P.R.,
Yang Y.,
Villen J.,
Becker E.B.E.,
DiBacco S.,
de la Iglesia N.,
Gygi S.P.,
Blackwell T.K.,
Bonni A.;
"A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span.";
Cell 125:987-1001(2006).
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[8]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-421 AND THR-427, AND MASS SPECTROMETRY.
DOI=10.1021/pr0705441; PubMed=18220336 [NCBI, ExPASy, EBI, Israel, Japan]
Cantin G.T.,
Yi W.,
Lu B.,
Park S.K.,
Xu T.,
Lee J.-D.,
Yates J.R. III;
"Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.";
J. Proteome Res. 7:1346-1351(2008).
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[9]
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PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-280 AND SER-284, AND MASS SPECTROMETRY.
DOI=10.1073/pnas.0805139105; PubMed=18669648 [NCBI, ExPASy, EBI, Israel, Japan]
Dephoure N.,
Zhou C.,
Villen J.,
Beausoleil S.A.,
Bakalarski C.E.,
Elledge S.J.,
Gygi S.P.;
"A quantitative atlas of mitotic phosphorylation.";
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
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[10]
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IDENTIFICATION [LARGE SCALE ANALYSIS], AND MASS SPECTROMETRY.
Colinge J.,
Superti-Furga G.,
Bennett K.L.;
Submitted (OCT-2008) to UniProtKB.
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[11]
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X-RAY CRYSTALLOGRAPHY (2.7 ANGSTROMS) OF 158-253 IN COMPLEX WITH DNA, MUTAGENESIS OF LYS-242 AND LYS-245, AND NUCLEAR LOCALIZATION SIGNAL.
DOI=10.1093/nar/gkm703; PubMed=17940099 [NCBI, ExPASy, EBI, Israel, Japan]
Tsai K.-L.,
Sun Y.-J.,
Huang C.-Y.,
Yang J.-Y.,
Hung M.-C.,
Hsiao C.-D.;
"Crystal structure of the human FOXO3a-DBD/DNA complex suggests the effects of post-translational modification.";
Nucleic Acids Res. 35:6984-6994(2007).
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