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UniProtKB/Swiss-Prot entry O14137


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name G6PD3_SCHPO
Primary accession number O14137
Secondary accession numbers None
Integrated into Swiss-Prot on May 20, 2008
Sequence was last modified on January 1, 1998 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 50)
Name and origin of the protein
Protein name Probable glucose-6-phosphate 1-dehydrogenase C7.13c
Synonyms G6PD
EC 1.1.1.49
Gene name
ORFNames: SPAC3C7.13c
From
Schizosaccharomyces pombe (Fission yeast) [TaxID: 4896] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 38366 / 972;
DOI=10.1038/nature724; PubMed=11859360 [NCBI, ExPASy, EBI, Israel, Japan]
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M., Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.;
"The genome sequence of Schizosaccharomyces pombe.";
Nature 415:871-880(2002).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CU329670; CAB16743.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR T38699; T38699.
RefSeq NP_593614.1; -.
3D structure databases
HSSP P11413; 1QKI. [HSSP ENTRY / PDB]
ModBase O14137.
Organism-specific databases
GeneDB_Spombe SPAC3C7.13c; -.
Gene expression databases
ArrayExpress O14137; -.
Ontologies
GO
GO:0006010; Biological process: glucose 6-phosphate utilization (inferred by curator from GeneDB_SPombe).
GO:0009051; Biological process: pentose-phosphate shunt, oxidative branch (inferred by curator from GeneDB_SPombe).
QuickGo view.
Family and domain databases
InterPro IPR001282; Glc-6-P_DHase.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
PANTHER PTHR23429; G6PDH; 1.
Pfam PF02781; G6PD_C; 1.
PF00479; G6PD_N; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000110; G6PD; 1.
PRINTS PR00079; G6PDHDRGNASE.
ProDom PD001129; G6PD; 1.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR00871; zwf; 1.
BLOCKS O14137.
Genome annotation databases
GeneID 2543207; -.
KEGG spo:SPAC3C7.13c; -.
NMPDR fig|4896.1.peg.3584; -.
Other
ProtoNet O14137.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Carbohydrate metabolism; Complete proteome; Cytoplasm; Glucose metabolism; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   473  473     Probable glucose-6-phosphate 1-dehydrogenase C7.13c. PRO_0000337688
ACT_SITE   237   237        Proton acceptor (By similarity). 
BINDING   10    10        NADP (By similarity). 
BINDING   43    43        NADP (By similarity). 
BINDING   174   174        Substrate (By similarity). 
BINDING   178   178        Substrate (By similarity). 
Sequence information
Length: 473 AA [This is the length of the unprocessed precursor] Molecular weight: 54430 Da [This is the MW of the unprocessed precursor] CRC64: D932A886A65CE62F [This is a checksum on the sequence]
        10         20         30         40         50         60 
MVTFMVFGAS GNLANKKTFP ALFHLFKRNL VDRSSFYVLG YARSKIPIGE FRESIRESVK 

        70         80         90        100        110        120 
PDTESKQVFQ DFIDRVSYFS GQYDQSSSYV EFRKHLESVE KKADSSKALR IFYIALPPSV 

       130        140        150        160        170        180 
YVTVSSHIYE NLYLPGKSRL VIEKPFGKNY QSAVKLKEEV HKHWKEEEIY RIDHYTAKDM 

       190        200        210        220        230        240 
VNNFFTLRFA NSSSIDAVLN RHSIQSVEIH MYETGGCEGR IGYYDANGVV RDVVQNHLTQ 

       250        260        270        280        290        300 
IFCIAAMNEP KSASASDVRA EKVNLLKATR PASLKESMLG QYTTSEDGKI PGYLDLEGVP 

       310        320        330        340        350        360 
KDSKATTFAA STLHVDNDRW KGVPFVFVSG KRMKKGEVYI KYYFRLKDSG IFSDVKRRRY 

       370        380        390        400        410        420 
LILHVQPEEF VNLTCTINKP MTTDLQPIDA YASLNYNEQF KDLMKEKRDG YEILFEDAIR 

       430        440        450        460        470 
GDPTKFIRYD EVEYAWKIWD EILDSPKKPI PYPAGSDGPE GLEAYMKRHL GHE 

O14137 in FASTA format

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