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UniProtKB/Swiss-Prot entry B0CHI7


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name TYSY_BRUSI
Primary accession number B0CHI7
Secondary accession numbers None
Integrated into Swiss-Prot on May 20, 2008
Sequence was last modified on February 26, 2008 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 7)
Name and origin of the protein
Protein name Thymidylate synthase
Synonyms TS
TSase
EC 2.1.1.45
Gene name
Name: thyA
OrderedLocusNames: BSUIS_A1450
From
Brucella suis (strain ATCC 23445 / NCTC 10510) [TaxID: 470137] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Brucellaceae; Brucella.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Setubal J.C., Bowns C., Boyle S., Crasta O.R., Czar M.J., Dharmanolla C., Gillespie J.J., Kenyon R.W., Lu J., Mane S., Mohapatra S., Nagrani S., Purkayastha A., Rajasimha H.K., Shallom J.M., Shallom S., Shukla M., Snyder E.E., Sobral B.W., Wattam A.R., Will R., Williams K., Yoo H., Bruce D., Detter C., Munk C., Brettin T.S.;
"Brucella suis ATCC 23445 whole genome shotgun sequencing project.";
Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000911; ABY38488.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_001628058.1; -.
3D structure databases
ModBase B0CHI7.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0004799; Molecular function: thymidylate synthase activity (inferred from electronic annotation from HAMAP).
GO:0006231; Biological process: dTMP biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00008; -; 1.
PBIL [Tree]
InterPro IPR000398; Thymidylat_synth_C.
Graphical view of domain structure.
Gene3D G3DSA:3.30.572.10; Thymidylat_synth_C; 1.
PANTHER PTHR11549:SF2; Thymidylat_synth_C; 1.
ProDom PD001180; Thymidylat_synth; 1.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR03284; thym_sym; 1.
PROSITE PS00091; THYMIDYLATE_SYNTHASE; 1.
BLOCKS B0CHI7.
ProtoNet B0CHI7.
Genome annotation databases
GeneID 5838419; -.
GenomeReviews CP000911_GR; BSUIS_A1450.
KEGG bmt:BSUIS_A1450; -.
CMR B0CHI7; BSUIS_A1450.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; Methyltransferase; Nucleotide biosynthesis; Transferase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   264  264     Thymidylate synthase. PRO_1000073870
ACT_SITE   146   146        By similarity. 
Sequence information
Length: 264 AA [This is the length of the unprocessed precursor] Molecular weight: 30330 Da [This is the MW of the unprocessed precursor] CRC64: FECAD558B5EDCAFA [This is a checksum on the sequence]
        10         20         30         40         50         60 
MRTYLDLLQH VLDHGVDRDD RTGTGTRSVF GYQMRFDLEE GFPVLTTKKL HLRSIIHELL 

        70         80         90        100        110        120 
WFLKGDTNIA YLKENGVTIW DEWADENGDL GPVYGYQWRS WPAPDGRHID QIANLLKMLH 

       130        140        150        160        170        180 
TNPQSRRLIV SAWNPALVDE MALPPCHCLF QFYVANGRLS CQLYQRSADI FLGVPFNIAS 

       190        200        210        220        230        240 
YALLTMMIAQ VTGLKPGEFI HTLGDAHIYS NHFEQARLQL TRTPKKLPVM HINPDVKDLF 

       250        260 
AFRFEDFRLD GYEADPTIKA PIAV 

B0CHI7 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

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