[1]	NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. McClelland M., Sanderson E.K., Porwollik S., Spieth J., Clifton W.S., Fulton R., Cordes M., Wollam A., Shah N., Pepin K., Bhonagiri V., Nash W., Johnson M., Thiruvilangam P., Wilson R.; Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases.

Comments

CATALYTIC ACTIVITY: ATP + uridine = ADP + UMP.
CATALYTIC ACTIVITY: ATP + cytidine = ADP + CMP.
PATHWAY: Pyrimidine metabolism; CTP biosynthesis via salvage pathway; CTP from cytidine: step 1/3 .
PATHWAY: Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uridine: step 1/1 .
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
SIMILARITY: Belongs to the uridine kinase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

CP000886; ABX66327.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

YP_001587161.1; -.

3D structure databases

ModBase

A9N7M0.

Ontologies

GO:0005737;	Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0005524;	Molecular function: ATP binding (inferred from electronic annotation from HAMAP).
GO:0004849;	Molecular function: uridine kinase activity (inferred from electronic annotation from HAMAP).
GO:0008655;	Biological process: pyrimidine salvage (inferred from electronic annotation from HAMAP).
QuickGo view.

Family and domain databases

HAMAP

MF_00551; -; 1.
PBIL [Tree]

InterPro

IPR000764; Uridine_kin.
Graphical view of domain structure.

PANTHER

PTHR10285:SF6; Uridine_kin; 1.

PRINTS

PR00988; URIDINKINASE.

TIGR00235; udk; 1.

Genome annotation databases

GeneID

5781961; -.

GenomeReviews

CP000886_GR; SPAB_00905.

KEGG

spq:SPAB_00905; -.

CMR

A9N7M0; SPAB_00905.

Other

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

ATP-binding; Complete proteome; Cytoplasm; Kinase; Nucleotide-binding; Transferase.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 213`	`213`	`Uridine kinase.`	`PRO_1000081969`
`NP_BIND`	`15 22`	`8`	`ATP (Potential).`

Sequence information

Length: 213 AA [This is the length of the unprocessed precursor]

Molecular weight: 24498 Da [This is the MW of the unprocessed precursor]

CRC64: E03F8A1A9864A1EA [This is a checksum on the sequence]

        10         20         30         40         50         60 
MTDQSHQCVI IGIAGASASG KSLIASTLYR ELREQVGDEH IGVIPEDSYY KDQSHLSMEE 

        70         80         90        100        110        120 
RVKTNYDHPN AMDHSLLFQH LQALKRGSAI ELPVYSYVEH TRMQETVRVE PKKVIILEGI 

       130        140        150        160        170        180 
LLLTDARLRE EMNFSIFVDT PLDICLMRRI KRDVNERGRS MDSVMAQYQK TVRPMFLQFI 

       190        200        210 
EPSKQYADII VPRGGKNRIA IDILKAKISQ FFE

A9N7M0 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools