[1]	NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. McClelland M., Sanderson E.K., Porwollik S., Spieth J., Clifton W.S., Fulton R., Cordes M., Wollam A., Shah N., Pepin K., Bhonagiri V., Nash W., Johnson M., Thiruvilangam P., Wilson R.; Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases.

Comments

FUNCTION: Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity).
CATALYTIC ACTIVITY: ATP + N-acetyl-D-glucosamine = ADP + N-acetyl-D-glucosamine 6-phosphate.
PATHWAY: Cell wall biogenesis; peptidoglycan recycling .
SIMILARITY: Belongs to the ROK (nagC/xylR) family. NagK subfamily.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

CP000886; ABX67681.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

YP_001588514.1; -.

3D structure databases

ModBase

A9N4M6.

Ontologies

GO:0005524;	Molecular function: ATP binding (inferred from electronic annotation from HAMAP).
GO:0045127;	Molecular function: N-acetylglucosamine kinase activity (inferred from electronic annotation from HAMAP).
GO:0008270;	Molecular function: zinc ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0006044;	Biological process: N-acetylglucosamine metabolic process (inferred from electronic annotation from HAMAP).
GO:0009254;	Biological process: peptidoglycan turnover (inferred from electronic annotation from HAMAP).
QuickGo view.

Family and domain databases

HAMAP

MF_01271; -; 1.
PBIL [Tree]

PS01125; ROK; 1.

Genome annotation databases

GeneID

5780790; -.

GenomeReviews

CP000886_GR; SPAB_02298.

KEGG

spq:SPAB_02298; -.

CMR

A9N4M6; SPAB_02298.

Other

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

ATP-binding; Carbohydrate metabolism; Complete proteome; Kinase; Metal-binding; Nucleotide-binding; Transferase; Zinc.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 303`	`303`	`N-acetyl-D-glucosamine kinase.`	`PRO_1000085843`
`NP_BIND`	`4 11`	`8`	`ATP (Potential).`
`NP_BIND`	`133 140`	`8`	`ATP (Potential).`
`METAL`	`157 157`		`Zinc (By similarity).`
`METAL`	`177 177`		`Zinc (By similarity).`
`METAL`	`179 179`		`Zinc (By similarity).`
`METAL`	`184 184`		`Zinc (By similarity).`

Sequence information

Length: 303 AA [This is the length of the unprocessed precursor]

Molecular weight: 32992 Da [This is the MW of the unprocessed precursor]

CRC64: 3C3F52B1A63F5468 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MYYGFDIGGT KIALGVFDST RRLQWEKRVP TPHTSYSAFL DAVCELVAEA DQRFGVKGSV 

        70         80         90        100        110        120 
GIGIPGMPET EDGTLYAANV PAASGKPLRA DLSARLDRDV RLDNDANCFA LSEAWDDEFT 

       130        140        150        160        170        180 
QYPLVMGLIL GTGVGGGLVL NGKPITGQSY ITGEFGHMRL PVDALTLMGF DFPLRRCGCG 

       190        200        210        220        230        240 
QMGCIENYLS GRGFAWLYQH YYDQSLQAPE IIALWEQGDE QAQAHVERYL NLLAVCLGNI 

       250        260        270        280        290        300 
LTIVDPDLLV IGGGLSNFTA ITTQLAERLP RHLLPVARAP RIERARHGDA GGMRGAAFLH 


LTD

A9N4M6 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools