NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1038/ng.2007.38; PubMed=18037886 [NCBI, ExPASy, EBI, Israel, Japan]
Saenz H.L., Engel P., Stoeckli M.C., Lanz C., Raddatz G., Vayssier-Taussat M., Birtles R., Schuster S.C., Dehio C.;
"Genomic analysis of Bartonella identifies type IV secretion systems as host adaptability factors.";
Nat. Genet. 39:1469-1476(2007).

Comments

CATALYTIC ACTIVITY: Carbamoyl phosphate + L-aspartate = phosphate + N-carbamoyl-L-aspartate.
PATHWAY: Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from HCO(3)(-): step 2/6 .
SIMILARITY: Belongs to the ATCase/OTCase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

AM260525; CAK01511.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

YP_001609506.1; -.

3D structure databases

ModBase

A9IU46.

Ontologies

GO:0004070;	Molecular function: aspartate carbamoyltransferase activity (inferred from electronic annotation from HAMAP).
GO:0006221;	Biological process: pyrimidine nucleotide biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.

Family and domain databases

HAMAP

MF_00001; -; 1.
PBIL [Tree]

InterPro

IPR006130; Asp/Orn_carbamoyltranf.
IPR002082; Aspartate_carbamoyltransf_euk.
Graphical view of domain structure.

PRINTS

PR00100; AOTCASE.
PR00101; ATCASE.

TIGRFAMs

TIGR00670; asp_carb_tr; 1.

PROSITE

PS00097; CARBAMOYLTRANSFERASE; 1.

BLOCKS

A9IU46.

Genome annotation databases

GeneID

5830102; -.

GenomeReviews

AM260525_GR; BT1139.

CMR

A9IU46; BT1139.

Other

ProtoNet

A9IU46.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; Pyrimidine biosynthesis; Transferase.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 321`	`321`		`Aspartate carbamoyltransferase.`	`PRO_1000073720`

Sequence information

Length: 321 AA [This is the length of the unprocessed precursor]

Molecular weight: 35148 Da [This is the MW of the unprocessed precursor]

CRC64: DBF31B0EB9CB5603 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MIQDNFFPLF PHKHLLAIKD LSVQDLNTLL DRAEANVILS NKIDKTKSIL RGRTQINLFF 

        70         80         90        100        110        120 
EASTRTQSSF ELAGKRLGAD VISVAIGNSS VKKGETLFDT AATLNAMKPD ILVFRHSSAG 

       130        140        150        160        170        180 
AAALLAQKVD CCVINAGDGA HEHPTQALLD ALTIKRAKGR IEGLTVAICG DILHSRVARS 

       190        200        210        220        230        240 
NILSLNALGA RVRAVAPSTL LPTEINHMSV EVFNTMKDGL KDADVIMMLR LQHERMTGSF 

       250        260        270        280        290        300 
IPSTREYFHY FGLHKENLTY AKNNCIILHP GPINRGVEIA SDIADGPQSM IRTQVEMGIA 

       310        320 
VRMAVMEALL DSRLKINGEK K

A9IU46 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools